Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Adeboye O, Osunkoya"'
Autor:
Viraj A. Master, Benjamin N. Schmeusser, Adeboye O. Osunkoya, Arnold R. Palacios, Eric Midenberg, Lauren Yantorni, Kenneth Ogan, Mehmet A. Bilen
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 50-55 (2023)
Renal cell carcinoma with level IV tumor thrombus is a condition necessitating aggressive surgical management. Many solid organ malignancies often benefit from neoadjuvant treatments for tumor debulking and improvement of surgical outcomes. However,
Externí odkaz:
https://doaj.org/article/2cfee0fda685443bbd43014795ab61f2
Autor:
Mahmut Akgul, Robert Humble, Abdullah Osme, Servet Yuce, Elif N. Kocak, Parisa Najafzadeh, Ankur Sangoi, Niharika Pattnaik, Sourav Mishra, Shivani Sharma, Nada Shaker, Seema Kaushal, Manas Baisakh, Andrea R. Lightle, Bonnie L. Balzer, Guang-Qian Xiao, Gregory T. MacLennan, Adeboye O. Osunkoya, Anil Parwani, Liang Cheng, Andrew Bellizzi, Sambit K. Mohanty
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-9 (2022)
Highlights Clear cell adenocarcinoma of the lower urinary tract is rare, with heterogenous morphology. GATA3 expression can be seen in these tumors, causing diagnostic challenge in the urinary tract or in the metastatic setting. Along with morphologi
Externí odkaz:
https://doaj.org/article/a13b80eadd6f4057b0a3d25f73462a24
Autor:
Soheil Soltani, Ashkan Ojaghi, Hui Qiao, Nischita Kaza, Xinyang Li, Qionghai Dai, Adeboye O. Osunkoya, Francisco E. Robles
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Identifying prostate cancer patients that are harboring aggressive forms of prostate cancer remains a significant clinical challenge. Here we develop an approach based on multispectral deep-ultraviolet (UV) microscopy that provides novel qua
Externí odkaz:
https://doaj.org/article/7d7c1da235724a938c6500d1c3b44d61
Autor:
Antonio Rodriguez-Calero, John Gallon, Dilara Akhoundova, Sina Maletti, Alison Ferguson, Joanna Cyrta, Ursula Amstutz, Andrea Garofoli, Viola Paradiso, Scott A. Tomlins, Ekkehard Hewer, Vera Genitsch, Achim Fleischmann, Erik Vassella, Elisabeth J. Rushing, Rainer Grobholz, Ingeborg Fischer, Wolfram Jochum, Gieri Cathomas, Adeboye O. Osunkoya, Lukas Bubendorf, Holger Moch, George Thalmann, Charlotte K. Y. Ng, Silke Gillessen, Salvatore Piscuoglio, Mark A. Rubin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The diagnosis of prostate cancer brain metastasis (PCBM) has increased. Here, the authors investigate the landscape of somatic genetic alterations in brain metastases in a PCBM cohort of 51 patients with non-synchronous matched primary samples availa
Externí odkaz:
https://doaj.org/article/42966ddd44de4ed4a87861f3d4c3176c
Autor:
Baotong Zhang, Yixiang Li, Qiao Wu, Lin Xie, Benjamin Barwick, Changying Fu, Xin Li, Daqing Wu, Siyuan Xia, Jing Chen, Wei Ping Qian, Lily Yang, Adeboye O. Osunkoya, Lawrence Boise, Paula M. Vertino, Yichao Zhao, Menglin Li, Hsiao-Rong Chen, Jeanne Kowalski, Omer Kucuk, Wei Zhou, Jin-Tang Dong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The therapies for bone metastatic prostate cancer are limited and the underlying mechanisms are unclear. Here, the authors show that bone derived TGF-β induces acetylation of KLF5 (Ac-KLF5), and Ac-KLF5 promotes prostate cancer bone metastasis and r
Externí odkaz:
https://doaj.org/article/4767d9e2f20b432ab88e90cb4777af44
Autor:
James Robert Janopaul-Naylor, Jim Zhong, Yuan Liu, Chao Zhang, Adeboye O. Osunkoya, Shreyas Subhash Joshi, Mehmet Asim Bilen, Bradley Carthon, Omer Kucuk, Lindsey Marie Hartsell, Joseph Shelton, Ashesh B. Jani
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 26, Iss , Pp 30-34 (2021)
Purpose: For muscle-invasive bladder cancer, bladder preserving chemoradiotherapy (BPCRT) has shown to be a viable alternative for patients with urothelial carcinoma (UCa). Traditionally bladder cancer with variant histology UCa or other tumors types
Externí odkaz:
https://doaj.org/article/1e85af579fb94ecd921ae759aa66683e
Autor:
Baotong Zhang, Xinpei Ci, Ran Tao, Jianping Jenny Ni, Xiaoyan Xuan, Jamie L. King, Siyuan Xia, Yixiang Li, Henry F. Frierson, Dong-Kee Lee, Jianming Xu, Adeboye O. Osunkoya, Jin-Tang Dong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The role of the Klf5 in early and postnatal prostate development and in regeneration is unclear. Here, the authors show that Klf5 acetylation regulates and maintains luminal differentiation of prostate basal progenitors and is essential following and
Externí odkaz:
https://doaj.org/article/f0e28e9d788c4ece9cb9e8d8bdcafded
Publikováno v:
BME Frontiers, Vol 2022 (2022)
Objective and Impact Statement. Identifying benign mimics of prostatic adenocarcinoma remains a significant diagnostic challenge. In this work, we developed an approach based on label-free, high-resolution molecular imaging with multispectral deep ul
Externí odkaz:
https://doaj.org/article/ac939ef5ccd646fb821ab062c079b64f
Autor:
Zhenghong Li, Carrie Sun, Sijia Tao, Adeboye O. Osunkoya, Rebecca S. Arnold, John A. Petros, Xiongbing Zu, Carlos S. Moreno
Publikováno v:
Translational Oncology, Vol 13, Iss 4, Pp - (2020)
In our previous study, we observed that androgen deprivation therapy (ADT) may induce a compensatory increase in MAPK or JNK signaling. Here, we tested the effects of the MEK inhibitors PD0325901 and GSK1120212, ERK1/2 inhibitor GDC-0994, and the JNK
Externí odkaz:
https://doaj.org/article/b5534da476654170a8fe631f6ae4cb67
Autor:
Viraj A. Master, Benjamin N. Schmeusser, Adeboye O. Osunkoya, Arnold R. Palacios, Eric Midenberg, Lauren Yantorni, Kenneth Ogan, Mehmet A. Bilen
Publikováno v:
Journal of Immunotherapy and Precision Oncology. 6:50-55
Renal cell carcinoma with level IV tumor thrombus is a condition necessitating aggressive surgical management. Many solid organ malignancies often benefit from neoadjuvant treatments for tumor debulking and improvement of surgical outcomes. However,