Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Adebola Giwa"'
Autor:
Ravi Savarirayan, Daniel G. Hoernschemeyer, Merete Ljungberg, Yuri A. Zarate, Carlos A. Bacino, Michael B. Bober, Janet M. Legare, Wolfgang Högler, Teresa Quattrin, M. Jennifer Abuzzahab, Paul L. Hofman, Klane K. White, Nina S. Ma, Dirk Schnabel, Sérgio B. Sousa, Meng Mao, Alden Smith, Mukta Chakraborty, Adebola Giwa, Bent Winding, Birgitte Volck, Aimee D. Shu, Ciara McDonnell
Publikováno v:
EClinicalMedicine, Vol 65, Iss , Pp 102258- (2023)
Summary: Background: TransCon CNP (navepegritide) is an investigational prodrug of C-type natriuretic peptide (CNP) designed to allow for continuous CNP exposure with once-weekly dosing. This 52-week phase 2 (ACcomplisH) trial assessed the safety and
Externí odkaz:
https://doaj.org/article/07498b64dfd0403e9988b282f640b406
Autor:
Rizwan Ahmed, Neha Majety, Kevin C. Chan, Adebola Giwa, Joseph Heinemann, Hao Zhang, Joseph Margolick, Rafid Al-Hallaf, Prajita Paul, David R. Bell, Yi Song, Sangyun Lee, Ruhong Zhou, Risa M Wolfe, Thomas Donner, Chunfa Jie, Abdel Rahim A Hamad
T and B cells are the two arms of the adaptive immune system that mediate cellular and humoral immunity, respectively, using highly diverse repertoires of antigen receptors. T cells recognize antigens using the T cell receptor (TCR), whereas B cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99923d1ff7e26a1e18e07ea7b86ad4a3
https://doi.org/10.1101/2023.05.06.539704
https://doi.org/10.1101/2023.05.06.539704
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/e902b22131674d9e8778b78ebdff5ebd
Publikováno v:
Cell
We have recently identified a novel lymphocyte that is a dual expresser (DE) of TCRαβ and BCR. DEs in T1D patients are predominated by a public BCR clonotype (clone-x) that encodes a potent autoantigen that cross-activates insulin-reactive T cells.
Autor:
Zahra Omidian, Thomas Donner, Sarah M Omer, Neha Majety, Abdel Rahim A. Hamad, Adebola Giwa, Kagan Ege Karakus, Rizwan Ahmed
Publikováno v:
World Journal of Diabetes
Type 1 diabetes (T1D) is an autoimmune disease that usually strikes early in life, but can affect individuals at almost any age. It is caused by autoreactive T cells that destroy insulin-producing beta cells in the pancreas. Epidemiological studies e
Publikováno v:
Cell Immunol
Interleukin-17 (IL-17) is a potent proinflammatory cytokine that protects a host against fungal and extracellular bacterial infections. On the other hand, excessive or dysregulated production of IL-17 underlines susceptibility to autoimmune disease.
Autor:
Adebola Giwa, Michael Beckert, Carl Decker, Janet M. Legare, Ravi Savririyan, Yuri A. Zarate, Ying Zhang, R William Charlton
Publikováno v:
Journal of the Endocrine Society. 5:A712-A713
Background: Achondroplasia (ACH) is the most common skeletal dysplasia and the most frequent form of dwarfism. ACH is caused by a gain-of-function mutation in the fibroblast growth factor receptor 3 (FGFR3) gene and results in impairment of the endoc
Autor:
Rizwan Ahmed, Zahra Omidian, Adebola Giwa, Kusuma Ananth, kagan Ege Karakus, Mahamoud Aljack, Neha Majety, Angela Yang, Alana Macdonald, Sanjana Tyagi, Hao Zhang, Hamid Rabb, Chunfa Jie, Thomas Donner, Abdel Hamad
Publikováno v:
The Journal of Immunology. 206:21.03-21.03
PURPOSE: We have recently identified a previously unknown lymphocyte that is a dual expresser (DE) of productively rearranged and surface-expressed TCRαβ and BCR (surface immunoglobulin, Ig) (Ahmed et al, Cell, 2019: 177:11583). Importantly, a sing
Autor:
Carl Decker, Josep Maria de Bergua, R William Charlton, Leanne M Ward, Ying Zhang, Marie-Eve Robinson, Adebola Giwa
Publikováno v:
Journal of the Endocrine Society
Background: Achondroplasia (ACH) is the most common form of dwarfism occurring in 1 in 22,000 births (95% CI 18,500 to 26,000). This skeletal dysplasia is caused by a gain-of-function mutation in the fibroblast growth factor receptor 3 (FGFR3) gene l
Autor:
Patrick Cahan, Stephen Desiderio, Scheherazade Sadegh-Nasseri, Simon Gritsch, Ruhong Zhou, Abdel Rahim A. Hamad, Neha Majety, David R. Bell, Adebola Giwa, Benjamin Cornwell, Aaron W. Michels, Zahra Omidian, Chunfa Jie, Rizwan Ahmed, Thomas Donner, Sangyun Lee, Hao Zhang, Mario L. Suvà, Hamid Rabb
Publikováno v:
Cell
T and B cells are the two known lineages of adaptive immune cells. Here, we describe a previously unknown lymphocyte that is a dual expresser (DE) of TCR and BCR and key lineage markers of both B and T cells. In type 1 diabetes (T1D), DEs are predomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e1f6d08b73000076baae0e3c65139e
https://europepmc.org/articles/PMC7962621/
https://europepmc.org/articles/PMC7962621/