Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Addolorata Coluccia"'
Autor:
Sara Sergio, Addolorata Coluccia, Ferruccio Pisanello, Enrico Domenico Lemma, Barbara Spagnolo, Massimo De Vittorio, Daniele Vergara, Michele Maffia
Publikováno v:
Acta Biomaterialia. 103:153-164
Mechanical cues sensed by tumor cells in their microenvironment can influence important mechanisms including adhesion, invasion and proliferation. However, a common mechanosensitive protein and/or pathway can be regulated in different ways among dive
Autor:
Te Liu, Michela Puxeddu, Antonio Coluccia, Ruoli Bai, Maria Stefania Sinicropi, Chiara Tremolanti, Romano Silvestri, Eleonora Da Pozzo, Stefano Biagioni, Jessica Sebastiani, Giuseppe La Regina, Addolorata Coluccia, Marianna Bufano, Viviana Orlando, Jessica Ceramella, Claudia Martini, Ernest Hamel, Domenico Iacopetta, Hongliang Shen, Diego Brancaccio, Marianna Nalli
Long-term survivors of glioblastoma multiforme (GBM) are at high risk of developing second primary neoplasms, including leukemia. For these patients, the use of classic tyrosine kinase inhibitors (TKIs), such as imatinib mesylate, is strongly discour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2cc1965583a22b1b8279efd43bb60b
http://hdl.handle.net/11568/1125851
http://hdl.handle.net/11568/1125851
Autor:
Giuseppe La Regina, Addolorata Coluccia, Carmela Mazzoccoli, Ruoli Bai, Claudia Martini, Cristina Mazzoni, Eleonora Da Pozzo, Romano Silvestri, Marianna Nalli, Michela Puxeddu, Te Liu, Hongliang Shen, Ernest Hamel, Chiara Cavallini, Viviana Orlando, Stefano Biagioni, Antonio Coluccia
Novel 3-aroyl-1,4-diarylpyrrole derivatives were synthesized to explore structure-activity relationships at the phenyls at positions 1 and 4 of the pyrrole. The presence of amino phenyl rings at positions 1 and 4 of the pyrrole ring were found to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa960ef07ea0c899c6bd314243fdf5a
http://hdl.handle.net/11573/1338485
http://hdl.handle.net/11573/1338485
Autor:
Viviana Orlando, Marta Baiocchi, Maria Laura De Angelis, Romano Silvestri, Giuseppe La Regina, Stefano Biagioni, Candice Gautier, Valentina Naccarato, Gianluca Canettieri, Laura Di Magno, Antonio Coluccia, Stefano Gianni, Fiorella Di Pastena, Addolorata Coluccia, Marianna Nalli
Publikováno v:
ACS Medicinal Chemistry Letters
Targeted approaches aiming at modulating NHERF1 activity, rather than its overall expression, would be preferred to preserve the normal functions of this versatile protein. We focused our attention on the NHERF1/PDZ1 domain that governs its membrane
Autor:
Michel Salzet, Valeria Famiglini, Concetta Saponaro, Luca Mologni, Giuseppe La Regina, Sara Sergio, Michele Maffia, Romano Silvestri, Candice Gautier, Valentina Naccarato, Addolorata Coluccia, Stefano Gianni, Antonio Coluccia, Carlo Gambacorti Passerini, Daniele Vergara, Maria De Luca, Cecilia Bucci, Isabelle Fournier, Daniela Bonetti
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2018, 37 (24), pp.3301-3316. ⟨10.1038/s41388-018-0170-y⟩
Oncogene, 2018, 37 (24), pp.3301-3316. ⟨10.1038/s41388-018-0170-y⟩
Oncogene, Nature Publishing Group, 2018, 37 (24), pp.3301-3316. ⟨10.1038/s41388-018-0170-y⟩
Oncogene, 2018, 37 (24), pp.3301-3316. ⟨10.1038/s41388-018-0170-y⟩
International audience; Nuclear activated β-catenin plays a causative role in colorectal cancers (CRC) but remains an elusive therapeutic target. Using human CRC cells harboring different Wnt/β-catenin pathway mutations in APC/KRAS or β-catenin/KR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f8cd9cc4ba519a29371c556fa639b4
http://hdl.handle.net/11573/1071891
http://hdl.handle.net/11573/1071891
Autor:
Ferruccio Pisanello, Barbara Spagnolo, Sara Sergio, Luciana Algieri, Enrico Domenico Lemma, Marco Pisanello, Maria Addolorata Coluccia, Michele Maffia, Massimo De Vittorio
Physical and mechanical properties of extracellular matrix (ECM) have been proved to be crucial in the metastatic process. However, currently available studies on the interplay between ECM stiffness and cancer cell invasive behaviour are performed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a228f4776531e28c5f39f64bdb715ba9
http://www.journals.elsevier.com/microelectronic-engineering/
http://www.journals.elsevier.com/microelectronic-engineering/
Autor:
Vitalba Ruggieri, Romano Silvestri, Michele Maffia, Giorgio Ortar, Mario Varasi, Addolorata Coluccia, Carmela Mazzoccoli, Marianna Nalli, Sara Passacantilli, Antonio Coluccia, Concetta Saponaro, Ciro Mercurio, Tiziana Tataranni, Stefania Vultaggio, Ruoli Bai, Andrea Brancale, Valeria Famiglini, Giuseppe La Regina, Sara Sergio, Ernest Hamel, Valentina Naccarato, Claudia Piccoli, Francesca Agriesti
We designed 3-aroyl-1,4-diarylpyrrole (ARDAP) derivatives as potential anticancer agents having different\ud substituents at the 1- or 4-phenyl ring. ARDAP compounds exhibited potent inhibition of tubulin polymerization, binding of\ud colchicine to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31abffa3386350904eea1af92e307fdb
http://hdl.handle.net/11573/954246
http://hdl.handle.net/11573/954246
Autor:
Giuseppe Petrosillo, Giuseppe Paradies, Michele Persichella, Consiglia Pacelli, Piero Portincasa, Tiziana Cocco, Antonio Massaro, Ignazio Grattagliano, Addolorata Coluccia, Emanuele De Nitto, Maria Rosaria Carratù, Pietro Borracci
Publikováno v:
The Journal of Nutrition. 140:1072-1079
Dietary choline deprivation (CD) is associated with behavioral changes, but mechanisms underlying these detrimental effects are not well characterized. For instance, no literature data are available concerning the CD effects on brain mitochondrial fu
Autor:
Ilaria Elena Palamà, Ross Rinaldi, Roberto Cingolani, Nicola Di Renzo, Carlo Gambacorti-Passerini, Stefano Leporatti, Giuseppe Gigli, Addolorata Coluccia, Michele Maffia, Emanuela de Luca
Publikováno v:
Nanomedicine (London. Online) 5 (2010): 419–431. doi:10.2217/nnm.10.8
info:cnr-pdr/source/autori:Ilaria Elena Palamà, Stefano Leporatti, Emanuela De Luca, Carlo Gambacorti-Passerini, Nicola Di Renzo, Michele Maffia, Ross Rinaldi, Giuseppe Gigli, Roberto Cingolani, and Addolorata M.L. Coluccia./titolo:Imatinib-Loaded polyelectrolyte microcapsules for sustained targeting of BCRABL+ leukemia stem cells/doi:10.2217%2Fnnm.10.8/rivista:Nanomedicine (London. Online)/anno:2010/pagina_da:419/pagina_a:431/intervallo_pagine:419–431/volume:5
Nanomedicine (Lond., Print) (2010).
info:cnr-pdr/source/autori:Palamà I.E., Leporatti S., de Luca E., Di Renzo N., Maffia M., Gambacorti-Passerini C., Rinaldi R., Gigli G., Cingolani R. and Coluccia A.M.L./titolo:Imatinib-loaded polyelectrolyte microcapsules for sustained targeting of BCR-ABL(+) leukemia stem cells/doi:/rivista:Nanomedicine (Lond., Print)/anno:2010/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Ilaria Elena Palamà, Stefano Leporatti, Emanuela De Luca, Carlo Gambacorti-Passerini, Nicola Di Renzo, Michele Maffia, Ross Rinaldi, Giuseppe Gigli, Roberto Cingolani, and Addolorata M.L. Coluccia./titolo:Imatinib-Loaded polyelectrolyte microcapsules for sustained targeting of BCRABL+ leukemia stem cells/doi:10.2217%2Fnnm.10.8/rivista:Nanomedicine (London. Online)/anno:2010/pagina_da:419/pagina_a:431/intervallo_pagine:419–431/volume:5
Nanomedicine (Lond., Print) (2010).
info:cnr-pdr/source/autori:Palamà I.E., Leporatti S., de Luca E., Di Renzo N., Maffia M., Gambacorti-Passerini C., Rinaldi R., Gigli G., Cingolani R. and Coluccia A.M.L./titolo:Imatinib-loaded polyelectrolyte microcapsules for sustained targeting of BCR-ABL(+) leukemia stem cells/doi:/rivista:Nanomedicine (Lond., Print)/anno:2010/pagina_da:/pagina_a:/intervallo_pagine:/volume
Aim: The lack of sensitivity of chronic myeloid leukemia (CML) stem cells to imatinib mesylate (IM) commonly leads to drug dose escalation or early disease relapses when therapy is stopped. Here, we report that packaging of IM into a biodegradable ca
Autor:
Addolorata Coluccia, Domenica Mangieri, Domenico Ribatti, Angelo Vacca, Mirco Ponzoni, Beatrice Nico
Publikováno v:
Cancer Letters. 277:199-204
In this study we purposed an alternative method to study the angiogenic and invasive potential of neuroblastoma cell suspensions implanted on the chick embryo chorioallantoic membrane (CAM) surface. Neuroblastoma cells were seeded in Matrigel and the