Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Adayabalam S. Balajee"'
Publikováno v:
Environmental Advances, Vol 9, Iss , Pp 100265- (2022)
Radiological /nuclear (R/N) mass casualty incidents can potentially expose several hundreds and thousands of humans to substantial doses of ionizing radiation (IR). Timely assessment of radiation dose is critical for making “life-saving” clinical
Externí odkaz:
https://doaj.org/article/f32c33ae3c5a4108ae3dd9bca5e596a0
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
DNA repair genes are critical for preserving genomic stability and it is well established that mutations in DNA repair genes give rise to progeroid diseases due to perturbations in different DNA metabolic activities. Cockayne Syndrome (CS) is an auto
Externí odkaz:
https://doaj.org/article/7d34b93e1a6f416f89d7fb4a7cfd4fb3
Autor:
Qunsong Tan, Kaifeng Niu, Yuqi Zhu, Zixiang Chen, Yueyang Li, Mengge Li, Di Wei, Adayabalam S. Balajee, Hongbo Fang, Yongliang Zhao
Publikováno v:
Oncogenesis, Vol 10, Iss 3, Pp 1-12 (2021)
Abstract Ubiquitination-dependent DNA damage response (DDR) signals play a critical role in the cellular choice of DNA damage repair pathways. Human DNA helicase RecQL4 participates in DNA replication and repair, and loss of RecQL4 is associated with
Externí odkaz:
https://doaj.org/article/b042317917fb42cdbbd72c4a0d9eadef
Autor:
Jacob T. Sanders, Trevor F. Freeman, Yang Xu, Rosela Golloshi, Mary A. Stallard, Ashtyn M. Hill, Rebeca San Martin, Adayabalam S. Balajee, Rachel Patton McCord
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Genomic aberrations disrupting chromosome spatial domains can lead to disease. Here, the authors investigate the impact of DNA damage response and repair on 3D genome folding, comparing wild type cells and ataxia telangiectasia mutated patient cells,
Externí odkaz:
https://doaj.org/article/b4ae77227af5466d8c9ab8117687906b
Autor:
Yongliang Zhao, Zhenfen Chi, Adayabalam S. Balajee, Srinivasan Madhusudan, Dileep N. Lobo, Arvind Arora, Mohammed A. Aleskandarany, Tienian Zhu, Shiyou Li, Meng Wu, Jing Liu, Kaifeng Niu, Hongbo Fang, Dongliang Mo
1. Supplementary Figure S1. PCR-SSCP analysis of 21 exons of human RecQL4 gene in human gastric cancer cell lines. 2. Supplementary Figure S2. PCR-SSCP analysis of 21 exons of human RecQL4 gene in human primary gastric tumors and matched gastric tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666a6ec3534a573677dc486229af744c
https://doi.org/10.1158/0008-5472.22406537.v1
https://doi.org/10.1158/0008-5472.22406537.v1
Autor:
Adayabalam S. Balajee, Vilhelm A. Bohr, Yongliang Zhao, Luca Proietti De-Santis, Gloria M. Calaf, Jarah A. Meador, Yanrong Su
Supplementary Methods and Materials, Figures 1-4 from Human RecQL4 Helicase Plays Critical Roles in Prostate Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5383d54ad9e482ee8568919de0a916a
https://doi.org/10.1158/0008-5472.22386140.v1
https://doi.org/10.1158/0008-5472.22386140.v1
Autor:
Yongliang Zhao, Zhenfen Chi, Adayabalam S. Balajee, Srinivasan Madhusudan, Dileep N. Lobo, Arvind Arora, Mohammed A. Aleskandarany, Tienian Zhu, Shiyou Li, Meng Wu, Jing Liu, Kaifeng Niu, Hongbo Fang, Dongliang Mo
1. Construction of Tissue Microarray (TMA). 2. Chemicals. 3. Real-time PCR. 4. Dual-Luciferase assay for MVP. 5. In vitro pull-down assay. 6. Co-immunoprecipitation. 7. Protein expression and purification. 8. Chromatin immunoprecipitation analysis 9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8482d57e3c9b20b7631189ff7e7892
https://doi.org/10.1158/0008-5472.22406534
https://doi.org/10.1158/0008-5472.22406534
Autor:
Yongliang Zhao, Zhenfen Chi, Adayabalam S. Balajee, Srinivasan Madhusudan, Dileep N. Lobo, Arvind Arora, Mohammed A. Aleskandarany, Tienian Zhu, Shiyou Li, Meng Wu, Jing Liu, Kaifeng Niu, Hongbo Fang, Dongliang Mo
Elevation of the DNA-unwinding helicase RECQL4, which participates in various DNA repair pathways, has been suggested to contribute to the pathogenicity of various human cancers, including gastric cancer. In this study, we addressed the prognostic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64800d1f0c27b38501257b6773a00faf
https://doi.org/10.1158/0008-5472.c.6507101
https://doi.org/10.1158/0008-5472.c.6507101
Autor:
Yongliang Zhao, Tom K. Hei, Govind Bhagat, Adayabalam S. Balajee, Hongbo Fang, Chyuansheng Lin, Cuidong Wang, Genze Shao, Gengyun Wen, Ye Zhang
Loss of TGFBI, a secreted protein induced by transforming growth factor-β, has been implicated in cell proliferation, tumor progression, and angiogenesis by in vitro studies. However, in vivo antitumor functions of TGFBI as well as the underlying mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d773616a86a8ecb94741af0ed63e77
https://doi.org/10.1158/0008-5472.c.6497825
https://doi.org/10.1158/0008-5472.c.6497825
Publikováno v:
Cytogenetic and Genome Research. 162:188-200
Currently, our knowledge of how different cell types in a tissue microenvironment respond to low and high linear energy transfer (LET) radiation is highly restricted. In this study, a comparative analysis was performed on γ-ray-induced DNA damage an