Výsledky vyhledávání - "Adawia A. Alousi"

The lifetime of inositol 1,4,5-trisphosphate in single cells

Autor: Stuart H. Thompson, Adawia A. Alousi, Samuel S.-H. Wang

Publikováno v: The Journal of General Physiology

In many eukaryotic cell types, receptor activation leads to the formation of inositol 1,4,5-trisphosphate (IP3) which causes calcium ions (Ca) to be released from internal stores. Ca release was observed in response to the muscarinic agonist carbacho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f330f5884329b4610ff29a10dd9c6974
https://doi.org/10.1085/jgp.105.1.149

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Reduced cardiac myofibrillar Mg-ATPase activity without changes in myosin isozymes in patients with end-stage heart failure

Autor: Alison M. Grant, Adawia A. Alousi, John R. Etzler, David B. Melvin, Barry R. Cofer, Joanna Van der Bel-Kahn

Publikováno v: Molecular and cellular biochemistry. 96(1)

In this study we tested the hypothesis that reduced myofibrillar ATPase activities in end-stage heart failure are associated with a redistribution of myosin isozymes. Cardiac myofibrils were isolated from left ventricular free wall from normal human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805d191ac2739733de0186b6d8b7ac2d
https://pubmed.ncbi.nlm.nih.gov/2146490

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Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency

Autor: Edward D. Pagani, Paul D. Allen, S W Dziuban, Adawia A. Alousi, A M Grant, T M Older

Publikováno v: Circulation Research. 63:380-385

Force development and shortening by cardiac muscle occur as a result of the interaction between actin and myosin within the myofibrillar lattice. This interaction is dependent upon intracellular ionized calcium and is controlled by the troponin-tropo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c9728207346b461e43bf8d4a12ce17
https://doi.org/10.1161/01.res.63.2.380

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Characterization of the Cardiotonic Effects of Milrinone, a New and Potent Cardiac Bipyridine, on Isolated Tissues from Several Animal Species

Autor: James C. Stuart, Louise H. Walton, Gerald P. Stankus, Adawia A. Alousi

Publikováno v: Journal of Cardiovascular Pharmacology. 5:804-811

The cardiotonic activity of milrinone (Win 47203), a potent analogue of amrinone, was demonstrated in isolated guinea pig, cat, rabbit, rat, and hamster atria and papillary muscles. Milrinone, in concentrations of 0.1-300 micrograms/ml, caused concen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc19bcd0a48705648fa044ca7a5b1478
https://doi.org/10.1097/00005344-198309000-00015

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The beneficial effect of amrinone on acute drug-induced heart failure in the anaesthetised dog

Autor: Adawia A. Alousi, Jay M. Canter, Dorothy J. Fort

Publikováno v: Cardiovascular Research. 19:483-494

Amrinone, a positive inotropic-vasodilator agent, was administered to anaesthetised dogs in an attempt to reverse heart failure induced by drugs possessing negative inotropic properties. Propranolol, a beta-adrenergic blocker; verapamil, a calcium sl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed37f6bf72821c94516b8af75a6082a
https://doi.org/10.1093/cvr/19.8.483

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Relationship between amrinone plasma concentration and cardiac index

Autor: Jerome Edelson, Adawia A Alousi, Charles E Biddlecome, Edmund H. Sonnenblick, Carol S. Maskin, Thierry H. LeJemtel

Publikováno v: Clinical Pharmacology and Therapeutics. 29:723-728

Amrinone was given to 14 patients with congestive heart failure as an intravenous bolus (1 mg/sec) at doses ranging from 0.5 to 3.5 mg/kg. Simultaneous determinations of cardiac index were made by thermodilution and of amrinone plasma concentration b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a75404a8df6ca7ec1dc511952c23089
https://doi.org/10.1038/clpt.1981.102

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Amrinone

Autor: Adawia A. Alousi, Hans P. Dobreck

Publikováno v: Cardiovascular Drug Reviews. 1:259-276

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3575c2fb85d069c14817fdc6de60513c
https://doi.org/10.1111/j.1527-3466.1983.tb00451.x

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New cardiotonic agents: A search for digitalis substitute

Autor: Adawia A. Alousi, Alfred E. Farah

Publikováno v: Life Sciences. 22:1139-1147

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e29dd18b598aecb47ecb30239990958
https://doi.org/10.1016/0024-3205(78)90083-8

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Differential Vasorelaxant Effects of Milrinone and Amrinone on Contractile Responses of Canine Coronary, Cerebral, and Renal Arteries

Autor: Dale B. Evans, Alison M. Grant, Alex L. Harris, Adawia A. Alousi, Paul J. Silver

Publikováno v: Journal of Cardiovascular Pharmacology. 13:238-244

The vasorelaxant effects of milrinone and amrinone in canine coronary, cerebral, and renal arterial rings or strips contracted by either K+-depolarization, U46619 (a thromboxane mimetic), or prostaglandin F2 alpha (PGF 2 alpha) were quantitated. Milr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccb8ef50a349931f06bd632303f80f4
https://doi.org/10.1097/00005344-198902000-00010

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