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of 38
pro vyhledávání: '"Adasme, Melissa F"'
Publikováno v:
In Seminars in Cancer Biology January 2021 68:192-198
Background: Structure-based drug repositioning has emerged as a promising alternative to conventional drug development. Regardless of the many success stories reported over the past years and the novel breakthroughs on the AI-based system AlphaFold f
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A88527
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https://tud.qucosa.de/api/qucosa%3A88527/attachment/ATT-0/
Autor:
Parisi, Daniele, Adasme, Melissa F., Sveshnikova, Anastasia, Bolz, Sarah Naomi, Moreau, Yves, Schroeder, Michael
Publikováno v:
In Computational and Structural Biotechnology Journal 2020 18:1043-1055
Akademický článek
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Autor:
Adasme, Melissa F.1 (AUTHOR), Parisi, Daniele2 (AUTHOR), Van Belle, Kristien3 (AUTHOR), Salentin, Sebastian1 (AUTHOR), Haupt, V. Joachim1,4 (AUTHOR), Jennings, Gary S.1 (AUTHOR), Heinrich, Jörg-Christian1 (AUTHOR), Herman, Jean3,5,6 (AUTHOR), Sprangers, Ben3,5,7 (AUTHOR), Louat, Thierry3 (AUTHOR), Moreau, Yves2 (AUTHOR), Schroeder, Michael1 (AUTHOR) michael.schroeder@tu-dresden.de
Publikováno v:
PLoS ONE. 5/27/2020, Vol. 15 Issue 5, p1-26. 26p.
Autor:
Zdrazil, Barbara, Felix, Eloy, Hunter, Fiona, Manners, Emma J, Blackshaw, James, Corbett, Sybilla, de Veij, Marleen, Ioannidis, Harris, Lopez, David Mendez, Mosquera, Juan F, Magarinos, Maria Paula, Bosc, Nicolas, Arcila, Ricardo, Kizilören, Tevfik, Gaulton, Anna, Bento, A Patrícia, Adasme, Melissa F, Monecke, Peter, Landrum, Gregory A, Leach, Andrew R
Publikováno v:
Nucleic Acids Research; 1/5/2024, Vol. 52 Issue D1, pD1180-D1192, 13p
Autor:
Salentin, Sebastian, Adasme, Melissa F., Heinrich, Jörg C., Haupt, V. Joachim, Daminelli, Simone, Zhang, Yixin, Schroeder, Michael
Publikováno v:
Scientific Reports (2017). 7
Drug repositioning identifies new indications for known drugs. Here we report repositioning of the malaria drug amodiaquine as a potential anti-cancer agent. While most repositioning efforts emerge through serendipity, we have devised a computational
Autor:
Adasme, Melissa F, Linnemann, Katja L, Bolz, Sarah Naomi, Kaiser, Florian, Salentin, Sebastian, Haupt, V Joachim, Schroeder, Michael
Publikováno v:
Nucleic Acids Research
With the growth of protein structure data, the analysis of molecular interactions between ligands and their target molecules is gaining importance. PLIP, the protein–ligand interaction profiler, detects and visualises these interactions and provide
Autor:
Adasme, Melissa F.
The rapid pace of scientific advances is enabling a greater understanding of diseases at the molecular level. In turn, the process for researching and developing new medicines is growing in difficulty, costs, and length as a result of the scientific,
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A75443
https://tud.qucosa.de/api/qucosa%3A75443/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A75443/attachment/ATT-0/
Autor:
Adasme, Melissa F., Bolz, Sarah Naomi, Adelmann, Lauren, Salentin, Sebastian, Haupt, V. Joachim, Moreno-Rodríguez, Adriana, Nogueda-Torres, Benjamín, Castillo-Campos, Verónica, Yepez-Mulia, Lilián, Fuentes-Vicente, José A. De, Rivera, Gildardo, Schroeder, Michael
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8809, p 8809 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences
Volume 21
Issue 22
Chagas disease, caused by the parasite Trypanosoma cruzi, affects millions of people in South America. The current treatments are limited, have severe side effects, and are only partially effective. Drug repositioning, defined as finding new indicati