Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Adarsha P. Malla"'
Autor:
Alexandra A. Seas, Adarsha P. Malla, Nima Sharifai, Jeffrey A. Winkles, Graeme F. Woodworth, Pavlos Anastasiadis
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1230 (2024)
Infiltrating gliomas are challenging to treat, as the blood-brain barrier significantly impedes the success of therapeutic interventions. While some clinical trials for high-grade gliomas have shown promise, patient outcomes remain poor. Microbubble-
Externí odkaz:
https://doaj.org/article/0c95eb4a03cc457db30f1c496d42149a
Autor:
Jeeun Kang, Haichong K. Zhang, Shilpa D. Kadam, Julie Fedorko, Heather Valentine, Adarsha P. Malla, Ping Yan, Maged M. Harraz, Jin U. Kang, Arman Rahmim, Albert Gjedde, Leslie M. Loew, Dean F. Wong, Emad M. Boctor
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Minimally-invasive monitoring of electrophysiological neural activities in real-time—that enables quantification of neural functions without a need for invasive craniotomy and the longer time constants of fMRI and PET—presents a very challenging
Externí odkaz:
https://doaj.org/article/88e9f4daf5b0498a9eb8f2fa991e57f4
Autor:
Maged M. Harraz, Adarsha P. Malla, Evan R. Semenza, Maria Shishikura, Manisha Singh, Yun Hwang, In Guk Kang, Young Jun Song, Adele M. Snowman, Pedro Cortés, Senthilkumar S. Karuppagounder, Ted M. Dawson, Valina L. Dawson, Solomon H. Snyder
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Cocaine is a monoamine transport inhibitor. Current models attributing pharmacologic actions of cocaine to inhibiting the activity of the amine transporters alone failed to translate to the clinic. Cocaine inhibition of the dopamine, ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fe02ba05d540959d3a5dc2d47bac82
https://doi.org/10.1073/pnas.2200545119
https://doi.org/10.1073/pnas.2200545119
Autor:
Hanh N. D. Le, Arthur L. Burnett, Adarsha P. Malla, Serkan Karakus, Jin U. Kang, Jeeun Kang, Maged M. Harraz, Emad M. Boctor
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Despite current progress achieved in the surgical technique of radical prostatectomy, post-operative complications such as erectile dysfunction and urinary incontinence persist at high incidence rates. In this paper, we present a methodology for func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbd7c938407be0053b2e37f7bea8018
http://link.springer.com/article/10.1038/s41598-020-63588-2
http://link.springer.com/article/10.1038/s41598-020-63588-2
Autor:
Michael D. Kornberg, Efrat Abramson, Maged M. Harraz, Moataz M. Gadalla, Robin Roychaudhuri, Adarsha P. Malla, Solomon H. Snyder, Evan R. Semenza, Chirag Vasavda
Publikováno v:
Proc Natl Acad Sci U S A
D-amino acids are increasingly recognized as important signaling molecules in the mammalian central nervous system. However, the D-stereoisomer of the amino acid with the fastest in vitro spontaneous racemization rate, cysteine, has not been examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5222acff2f2b29b6769ea63a5066254d
https://doi.org/10.1101/2021.07.05.451211
https://doi.org/10.1101/2021.07.05.451211
Autor:
Bindu D. Paul, Urbain Weyemi, Adarsha P. Malla, Maged M. Harraz, Deeya Bhattacharya, William M. Bonner, Solomon H. Snyder, Myriem Boufraqech
Publikováno v:
Proceedings of the National Academy of Sciences. 116:7471-7476
Phosphorylation of histone H2AX is a major contributor to efficient DNA repair. We recently reported neurobehavioral deficits in mice lacking H2AX. Here we establish that this neural failure stems from impairment of mitochondrial function and repress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab640f81a23f242d07cd8d4012989f7
https://doi.org/10.1073/pnas.1820245116
https://doi.org/10.1073/pnas.1820245116
Autor:
Adarsha P. Malla, Young Jun Song, Maged M. Harraz, Evan R. Semenza, Adele M. Snowman, Yun Hwang, In Guk Kang, Solomon H. Snyder, Pedro Cortés, Maria Shishikura
Cocaine is a behavioral stimulant with substantial abuse potential related to its positively rewarding actions1,2. Cocaine inhibits the reuptake inactivation of neurotransmitters such as dopamine, serotonin, and norepinephrine at high nanomolar to lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866d747f41ac00138254bd7443e4cadc
https://doi.org/10.1101/2020.11.23.392787
https://doi.org/10.1101/2020.11.23.392787
Autor:
Gianluigi Tanda, Solomon H. Snyder, Young Jun Song, Pedro Cortés, Prasun Guha, Luke Reilly, Mark A. Coggiano, Adarsha P. Malla, Maged M. Harraz, Vijayabhaskar Veeravalli, In Guk Kang, Isaac Treisman, Rana Rais, Evan R. Semenza
Publikováno v:
Mol Psychiatry
Cocaine exerts its stimulant effect by inhibiting dopamine reuptake leading to increased dopamine signaling. This action is thought to reflect binding of cocaine to the dopamine transporter (DAT) to inhibit its function. However, cocaine is a relativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc09ba8887fe59ad7dbfa0c6784da68
https://pubmed.ncbi.nlm.nih.gov/33414501
https://pubmed.ncbi.nlm.nih.gov/33414501
Autor:
Chenglai Fu, Weiwei Cheng, Tomas Rojas, Alfred C. Chin, Adarsha P. Malla, Xiaoqi Liu, Zhe Gao, Solomon H. Snyder, Yakun Wang, Lewis H. Romer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(8)
Cells express a family of three inositol hexakisphosphate kinases (IP6Ks). Although sharing the same enzymatic activity, individual IP6Ks mediate different cellular processes. Here we report that IP6K3 is enriched at the leading edge of migrating cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a40aea7f1bea147872bb4ec93bf7474
https://pubmed.ncbi.nlm.nih.gov/30718399
https://pubmed.ncbi.nlm.nih.gov/30718399
Autor:
Maged M. Harraz, In Guk Kang, Prasun Guha, Adarsha P. Malla, Pedro Cortés, Evan R. Semenza, Gianluigi Tanda, Young Jun Song, Mark A. Coggiano, Isaac Treisman, Solomon H. Snyder
Publikováno v:
Biological Psychiatry. 87:S261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba05425098c07da472e497ff52fbde3
https://doi.org/10.1016/j.biopsych.2020.02.675
https://doi.org/10.1016/j.biopsych.2020.02.675