Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adarsh R. Ettyreddy"'
Autor:
Jounghyun H. Lee, Kevin L. Shores, Jason J. Breithaupt, Caleb S. Lee, Daniella M. Fodera, Jennifer B. Kwon, Adarsh R. Ettyreddy, Kristin M. Myers, Benny J. Evison, Alexandra K. Suchowerska, Charles A. Gersbach, Kam W. Leong, George A. Truskey
Publikováno v:
APL Bioengineering, Vol 7, Iss 4, Pp 046103-046103-15 (2023)
Atherosclerosis is a primary precursor of cardiovascular disease (CVD), the leading cause of death worldwide. While proprotein convertase subtilisin/kexin 9 (PCSK9) contributes to CVD by degrading low-density lipoprotein receptors (LDLR) and altering
Externí odkaz:
https://doaj.org/article/f6d0b5cc6b244d04bac23d3123f01c78
Autor:
Jennifer B. Kwon, Adarsh R. Ettyreddy, Ashish Vankara, Joel D. Bohning, Garth Devlin, Stephen D. Hauschka, Aravind Asokan, Charles A. Gersbach
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 320-329 (2020)
Delivery of therapeutic transgenes with adeno-associated viral (AAV) vectors for treatment of myopathies has yielded encouraging results in animal models and early clinical studies. Although certain AAV serotypes efficiently target muscle fibers, tra
Externí odkaz:
https://doaj.org/article/027bf4f182644f8e99d5b59e596aa1d1
Publikováno v:
Stem Cell Reports
Summary Engineered CRISPR/Cas9-based transcriptional activators can potently and specifically activate endogenous fate-determining genes to direct differentiation of pluripotent stem cells. Here, we demonstrate that endogenous activation of the PAX7
Autor:
Shaunak S. Adkar, Adarsh R. Ettyreddy, Vincent P. Willard, Nidhi Bhutani, Amanda Dicks, Chia-Lung Wu, Charles A. Gersbach, Farshid Guilak, Nancy Steward
The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, disease modeling, and drug s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3a5cbe95a183b75e0cc26e2ef2d1ed
https://europepmc.org/articles/PMC6312762/
https://europepmc.org/articles/PMC6312762/
Autor:
Adarsh R. Ettyreddy, Katherine A. Glass, Jared R.L. Matthews, Christopher R. Rowland, Nguyen P.T. Huynh, Catherine C. Gloss, Farshid Guilak
Cartilage-derived matrix (CDM) has emerged as a promising scaffold material for tissue engineering of cartilage and bone due to its native chondroinductive capacity and its ability to support endochondral ossification. Because it consists of native t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f547c371162f3dc1cfa5e1c506287c45
Autor:
Jared R.L. Matthews, Nguyen P.T. Huynh, Christopher R. Rowland, Adarsh R. Ettyreddy, Katherine A. Glass, Catherine C. Gloss, Farshid Guilak
Publikováno v:
Biomaterials. 177
Cartilage-derived matrix (CDM) has emerged as a promising scaffold material for tissue engineering of cartilage and bone due to its native chondroinductive capacity and its ability to support endochondral ossification . Because it consists of native
Autor:
Adarsh R. Ettyreddy, Farshid Guilak, Charles A. Gersbach, Katherine A. Glass, Nguyen P.T. Huynh, Jonathan M. Brunger, Christopher R. Rowland
Publikováno v:
Molecular Therapy. 24:S199-S200
Objectives: Cartilage tissue engineering seeks to provide a functional replacement for damaged or degenerated articular surfaces that develop in osteoarthritis (OA). Human bone marrow-derived mesenchymal stem cells (MSCs) seeded within cartilage-deri