Strong and specific associations between cardiovascular risk factors and white matter micro- and macrostructure in healthy aging

Autor: Delia Fuhrmann, David Nesbitt, Meredith Shafto, James B. Rowe, Darren Price, Andrew Gadie, Rogier A. Kievit, Lorraine K. Tyler, Carol Brayne, Edward T. Bullmore, Andrew C. Calder, Rhodri Cusack, Tim Dalgleish, John Duncan, Richard N. Henson, Fiona E. Matthews, William D. Marslen-Wilson, Meredith A. Shafto, Karen Campbell, Teresa Cheung, Simon Davis, Linda Geerligs, Rogier Kievit, Anna McCarrey, Abdur Mustafa, David Samu, Jason R. Taylor, Matthias Treder, Kamen Tsvetanov, Janna van Belle, Nitin Williams, Lauren Bates, Tina Emery, Sharon Erzinlioglu, Sofia Gerbase, Stanimira Georgieva, Claire Hanley, Beth Parkin, David Troy, Tibor Auer, Marta Correia, Lu Gao, Emma Green, Rafael Henriques, Jodie Allen, Gillian Amery, Liana Amunts, Anne Barcroft, Amanda Castle, Cheryl Dias, Jonathan Dowrick, Melissa Fair, Hayley Fisher, Anna Goulding, Adarsh Grewal, Geoff Hale, Andrew Hilton, Frances Johnson, Patricia Johnston, Thea Kavanagh-Williamson, Magdalena Kwasniewska, Alison McMinn, Kim Norman, Jessica Penrose, Fiona Roby, Diane Rowland, John Sargeant, Maggie Squire, Beth Stevens, Aldabra Stoddart, Cheryl Stone, Tracy Thompson, Ozlem Yazlik, Dan Barnes, Marie Dixon, Jaya Hillman, Joanne Mitchell, Laura Villis

Publikováno v: Neurobiology of Aging
2019, ' Strong and specific associations between cardiovascular risk factors and white matter micro-and macrostructure in healthy aging ', Neurobiology of Aging, vol. 74, pp. 46-55 . https://doi.org/10.1016/j.neurobiolaging.2018.10.005

Cardiovascular health declines with age, increasing the risk of hypertension and elevated heart rate in middle and old age. Here, we used multivariate techniques to investigate the associations between cardiovascular health (diastolic blood pressure,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e09d15821e098e63658a2cd3692b1b0
http://europepmc.org/articles/PMC6338676

Age-related delay in visual and auditory evoked responses is mediated by white- and grey-matter differences

Autor: Darren Price, Fiona Roby, John Sargeant, Andrew C. Calder, Andrew Hilton, Kim Norman, Cheryl Dias, Liana Amunts, Stanimira Georgieva, Adarsh Grewal, Jonathan Dowrick, Tim Dalgleish, Ozlem Yazlik, Karen L. Campbell, Beth L. Parkin, Geoff Hale, Diane Rowland, Abdur Mustafa, Melissa Fair, James B. Rowe, Cheryl Stone, David Samu, Gillian Amery, Kamen A. Tsvetanov, Tibor Auer, Claire J. Hanley, Jodie Allen, Lorraine K. Tyler, Anna Goulding, Fiona E. Matthews, Laura Villis, Maggie Squire, John S. Duncan, Carol Brayne, David Troy, Hayley Fisher, Rogier A. Kievit, Sofia Gerbase, Amanda Castle, Jason R. Taylor, Thea Kavanagh-Williamson, Simon W. Davis, Alison McMinn, Anna McCarrey, Frances Johnson, Jaya Hillman, Janna van Belle, Joanne Mitchell, Anne Barcroft, Magdalena Kwasniewska, Sharon Erzinglioglu, Lauren Bates, Emma Green, Teresa Cheung, Beth Stevens, Marie Dixon, R. Neto Henriques, Rhodri Cusack, Nitin Williams, Meredith A. Shafto, Linda Geerligs, Marta Correia, Richard N. Henson, Matthias S. Treder, Andrew Gadie, Dan Barnes, Cam-CAN, Aldabra Stoddart, Jessica Penrose, Tina Emery, William D. Marslen-Wilson, Edward T. Bullmore, Patricia Johnston, Lu Gao, Tracy Thompson

Publikováno v: Nature Communications
Price, D, Tyler, L K, Henriques, R N, Campbell, K, Williams, N, Treder, M, Taylor, J, Cam-CAN & Henson, R N A 2017, ' Age-related delay in visual and auditory evoked responses is mediated by white-and gray-matter differences ', Nature Communications, vol. 8, 15671 . https://doi.org/10.1038/ncomms15671
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

Slowing is a common feature of ageing, yet a direct relationship between neural slowing and brain atrophy is yet to be established in healthy humans. We combine magnetoencephalographic (MEG) measures of neural processing speed with magnetic resonance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba51f8b65ce84e4bd99c240ef9ff743
https://orca.cardiff.ac.uk/id/eprint/108242/1/ncomms15671.pdf