MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype

Autor: Elsa Kress, Mathias Heikenwalder, Gerard Lina, David Bauché, Saskia Lippens, Claire Macari, Marie-Cécile Michallet, Mathias Chamaillard, Sophia Djebali, Emilie Plantamura, Lyvia Moudombi, Jacqueline Marvel, Christophe Caux, Julien C. Marie, Annabelle Cesaro, Lilia Boucinha, Amiran Dzutsev, Jean-Philippe Rasigade, Ulrike Rothermel, Giorgio Trinchieri, Azzak Bentaher-Belaaouaj, Oana Dumitrescu, Morgan Grau, Michelina Plateroti, Clovis Bondu

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (41), pp.10404-10409. ⟨10.1073/pnas.1722372115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (41), pp.10404-10409. ⟨10.1073/pnas.1722372115⟩

International audience; Prominent changes in the gut microbiota (referred to as "dysbiosis") play a key role in the development of allergic disorders, but the underlying mechanisms remain unknown. Study of the delayed-type hypersensitivity (DTH) resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f72c638beb7102ea94a7542c3c80f63
https://hal.science/hal-02398995

Cysteine-rich intestinal protein 2 ( CRIP2 ) acts as a repressor of NF-κB–mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis

Autor: Daniel Chua, Josephine Mun Yee Ko, Kwok Wah Chan, Eric J. Stanbridge, Arthur Kwok Leung Cheung, Hong Lok Lung, Maria Li Lung, Dora L.W. Kwong, Eugene R. Zabarovsky, Sai Wah Tsao, Lisa Kashima, Toshiharu Suzuki, Takashi Tokino

Publikováno v: Proceedings of the National Academy of Sciences. 108:8390-8395

Chromosome 14 was transferred into tumorigenic nasopharyngeal carcinoma and esophageal carcinoma cell lines by a microcell-mediated chromosome transfer approach. Functional complementation of defects present in the cancer cells suppressed tumor forma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ae8892994bd9cde179de170f1dd599
https://doi.org/10.1073/pnas.1101747108

Cutting Edge: Independent Roles for IRF-3 and IRF-7 in Hematopoietic and Nonhematopoietic Cells during Host Response to Chikungunya Infection

Autor: Matthew L. Albert, Matthew R. Buckwalter, Michael S. Diamond, Olivier Schwartz, Melissa E. Laird, Clémentine Schilte

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2012, 188 (7), pp.2967-2971. ⟨10.4049/jimmunol.1103185⟩
Journal of Immunology, 2012, 188 (7), pp.2967-2971. ⟨10.4049/jimmunol.1103185⟩

The host response to Chikungunya virus is dependent on the direct action of type I IFN on infected nonhematopoietic cells. Prior studies have demonstrated that multiple host sensors coordinate an antiviral response; however, the tissue source(s) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd355fa199660657f4633dcac80fed6a
https://hal-pasteur.archives-ouvertes.fr/pasteur-01372485