Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Adaptor Proteins, Signal Transducing/metabolism"'
Autor:
Tadashi Matsuda, Kenji Oritani
Publikováno v:
Biological & pharmaceutical bulletin. 44(12):1810-1818
The signal-transducing adaptor protein (STAP) family, including STAP-1 and STAP-2, contributes to a variety of intracellular signaling pathways. The proteins in this family contain typical structures for adaptor proteins, such as Pleckstrin homology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50783c353cfecf8a916e4c56a63b71e8
http://hdl.handle.net/2115/87612
http://hdl.handle.net/2115/87612
Autor:
Daan Dierickx, Philippe Gaulard, Carlos Graux, Koen Debackere, Laurence de Leval, Nicole Mentens, Jan Cools, Lucienne Michaux, Kris Jacobs, Thomas Tousseyn, Sofie Demeyer, Olga Gielen, Michaël Broux, Iwona Wlodarska, Marlies Vanden Bempt, Lukas Marcelis, Gregor Verhoef
Publikováno v:
Nature communications, vol. 12, no. 1, pp. 3705
Nature communications, Vol. 12, no.1, p. 3705 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature communications, Vol. 12, no.1, p. 3705 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of non-Hodgkin lymphomas with poor prognosis. Up to 30% of PTCL lack distinctive features and are classified as PTCL, not otherwise specified (PTCL-NOS). To further improve our understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133ce4ef8eab96b32fc1be9ac3896731
https://doi.org/10.1038/s41467-021-24037-4
https://doi.org/10.1038/s41467-021-24037-4
Autor:
Savita Dhanvantari, Y. Peng Loh, Stephanie Ma, Thanh V. Huynh, Stephen M. Hewitt, Niamh X. Cawley, Saravana R. K. Murthy, Irene Oi-Lin Ng, Robert Wesley, Terence K. Lee, Karel Pacak, Tracy Lau, Ronnie T.P. Poon, Hong Lou
Publikováno v:
The Journal of clinical investigation. 130
Metastasis is a major cause of mortality in cancer patients. However, the mechanisms governing the metastatic process remain elusive, and few accurate biomarkers exist for predicting whether metastasis will occur, something that would be invaluable f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8960c5e3dedcaa178cc44dc2822e8987
https://pubmed.ncbi.nlm.nih.gov/21285511
https://pubmed.ncbi.nlm.nih.gov/21285511
PubMed ID: 31247220 As seen in other types of cancer, development of drug resistance in NSCLC treatment causes adverse effects on disease fighting process. Recent studies have shown that one of the drug resistance development mechanisms is that cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b49c4e075c2253796d0e5168feb0836
https://doi.org/10.1016/j.gene.2019.06.025
https://doi.org/10.1016/j.gene.2019.06.025
Autor:
Martina Bosnar, Gordana Bubanović, Oliver Vugrek, Calogerina Catalano, Petar Ozretić, Miguel Inacio da Silva Filho, Lada Rumora, Sanda Škrinjarić-Cincar, Sanja Popović-Grle, Matea Kurtović, Marko Jakopović, Maja Šutić, Irena Jukić, Robert Bals, Andrea Vukić-Dugac, Astra Försti, Irena Sokolovic, Miroslav Samaržija, Jelena Knežević
Publikováno v:
Genes
Genes, Vol 10, Iss 10, p 783 (2019)
Volume 10
Issue 10
Genes, Vol 10, Iss 10, p 783 (2019)
Volume 10
Issue 10
Chronic obstructive pulmonary disease (COPD) is a chronic disease characterized by a progressive decline in lung function due to airflow limitation, mainly related to IL-1&beta
induced inflammation. We have hypothesized that single nucleotide po
induced inflammation. We have hypothesized that single nucleotide po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7b4d27e3db54e21fe0c5bf3b448eb5
http://fulir.irb.hr/5220/1/OzreticP_Association_Genes-10_2019_783.pdf
http://fulir.irb.hr/5220/1/OzreticP_Association_Genes-10_2019_783.pdf
Autor:
Hans Salwender, Marc Andrea Baertsch, Natalia Becker, Jan Dürig, Markus Munder, Katharina Kriegsmann, Mohamed H.S. Awwad, Katja Weisel, Jens Hillengass, Marc S. Raab, Anja Seckinger, Hartmut Goldschmidt, Roland Fenk, Maximilian Merz, Michael Hundemer, Carsten Müller-Tidow, Dirk Hose, Uta Bertsch, Axel Benner, Mathias Hänel, Anna Jauch
Publikováno v:
Blood Cancer Journal
Blood Cancer Journal, Vol 9, Iss 2, Pp 1-10 (2019)
Blood Cancer Journal, Vol 9, Iss 2, Pp 1-10 (2019)
Immunomodulatory drugs (IMIDs) are very effective in the treatment of multiple myeloma (MM). The description of their cereblon-mediated mechanism of action was a hallmark in MM research. Although the importance of IMID-induced degradation of cereblon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413ff4979dc7f236c8e400dfa7af308d
https://www.ncbi.nlm.nih.gov/pubmed/30696815
https://www.ncbi.nlm.nih.gov/pubmed/30696815
Autor:
Axel Bohring, Tae Joon Cho, Chong Ae Kim, Teresa Neuhann, Lesley C. Adès, Débora Romeo Bertola, Irma E Veenstra-Knol, Eva Morava, Erin Carter, Deborah Krakow, Aideen M. McInerney-Leo, Dagmar Wieczorek, Andrew J. Sutherland-Smith, Zandra A. Jenkins, Elaine Fletcher, Philip B. Daniel, Andrew O.M. Wilkie, Emma M. Wade, Tim M. Strom, Matthew A. Brown, Timothy R. Morgan, Raoul C.M. Hennekam, Stephen P. Robertson, David Markie, Hans Christoph Duba, Emma L. Duncan, Paul Leo, Louise C. Wilson, Andrea Superti-Furga, Marie-Claude Addor
Publikováno v:
Am. J. Hum. Genet. 99, 392-406 (2016)
American Journal of Human Genetics, 99(2), 392-406. CELL PRESS
American journal of human genetics, 99(2), 392-406. Cell Press
American journal of human genetics, vol. 99, no. 2, pp. 392-406
American Journal of Human Genetics, 99(2), 392-406. CELL PRESS
American journal of human genetics, 99(2), 392-406. Cell Press
American journal of human genetics, vol. 99, no. 2, pp. 392-406
Frontometaphyseal dysplasia (FMD) is a progressive sclerosing skeletal dysplasia affecting the long bones and skull. The cause of FMD in some individuals is gain-of-function mutations in FLNA, although how these mutations result in a hyperostotic phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d8549d944c149b7306c6dd504f8ab1
https://research.rug.nl/en/publications/ee18ca76-2bce-467e-880a-1b186e1ee45f
https://research.rug.nl/en/publications/ee18ca76-2bce-467e-880a-1b186e1ee45f
Autor:
Marta Mastrogiovanni, Paola Grazioli, Antonio Francesco Campese, Loretta Tuosto, Balbino Alarcón, Silvana Caristi, Cédric Favre, Nicla Porciello, Francesca Spadaro, Jacques A. Nunès, Isabella Screpanti, Martina Kunkl, Michela Muscolini, Aldo Borroto
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
CD28 superagonistic antibodies (CD28SAb) can preferentially activate and expand immunosuppressive regulatory T cells (Treg) in mice. However, pre-clinical trials assessing CD28SAbs for the therapy of autoimmune diseases reveal severe systemic inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29edf0332e8787c555c9b6ff4b29196e
https://hal.archives-ouvertes.fr/hal-01772994
https://hal.archives-ouvertes.fr/hal-01772994
Autor:
Gagnoux-Palacios, Laurent, Awina, Hala, Audebert, Stéphane, Rossin, Aurélie, Mondin, Magali, Borgese, Franck, Planas-Botey, Carlota, Mettouchi, Amel, Borg, Jean-Paul, Hueber, Anne-Odile
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, 2018, 217 (11), pp.3839-3852. ⟨10.1083/jcb.201805071⟩
The Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (11), pp.3839-3852. ⟨10.1083/jcb.201805071⟩
Journal of Cell Biology, 2018, 217 (11), pp.3839-3852. ⟨10.1083/jcb.201805071⟩
The Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (11), pp.3839-3852. ⟨10.1083/jcb.201805071⟩
Control of epithelial cell death is crucial to maintaining tissue integrity. Gagnoux-Palacios et al. show that cell polarity and adherens junction formation prevent proapoptotic signals emanating from the Fas death receptor. Therefore, Fas-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5b791786ff71a152338fb2a61cdb54f7
https://hal.science/hal-02374965/document
https://hal.science/hal-02374965/document
Autor:
Monica C. Dobocan, Filippa Pettersson, Christophe Goncalves, Marie-Noël M’Boutchou, Michael S. Dahabieh, Sonia V. del Rincón, Léon C van Kempen, Arjuna Rajakumar, Ivan Topisirovic, Wilson H. Miller, Shiru L. Lucy, Yao Zhan
Publikováno v:
Journal of Investigative Dermatology, 135(5), 1368-1376. ELSEVIER SCIENCE INC
In eukaryotic cells, the rate-limiting component for cap-dependent mRNA translation is the translation initiation factor eIF4E. eIF4E is overexpressed in a variety of human malignancies, but whether it has a role in melanoma remains obscure. We hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1754d4e7cfa6e6d5c25ab6516884520c