Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Adani Pujada"'
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Matrix metalloproteinase 9 (MMP9) limits reactive oxygen species (ROS) accumulation and DNA damage in colitis-associated cancer
Autor: Adani Pujada, Didier Merlin, Behafarin Arbasi, Tien Anh Bui, Brandon S.B. Canup, Hamed Laroui, Lewins Walter, Pallavi Garg
Publikováno v: Cell Death and Disease, Vol 11, Iss 9, Pp 1-14 (2020)
Cell Death & Disease
Colitis-associated cancer (CAC) is a subtype of colon cancer that is driven by chronic inflammation and is prevalent in chronic ulcerative colitis patients. The development of CAC is associated with the inflammation-dysplasia-carcinoma pathway which
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06a7f4e111a08ad7adf058557255f1d
http://link.springer.com/article/10.1038/s41419-020-02959-z
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2
Host-derived fecal microRNAs can indicate gut microbiota healthiness and ability to induce inflammation
Autor: Benoit Chassaing, Anika Tahsin, Andrew T. Gewirtz, Didier Merlin, Emilie Viennois, Adani Pujada, Lixin Wang
Publikováno v: Theranostics
Disruption of intestine-microbiota symbiosis can result in chronic gut inflammation. We hypothesize that assessing the initial inflammatory potential of the microbiota in patients is essential and that host-derived miRNAs, which can be found in feces
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603749a0b23636d47e50938f9d8697fb
https://doi.org/10.7150/thno.35282
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3
Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations
Autor: Benoit Chassaing, Junsik Sung, Andrew T. Gewirtz, Chunhua Yang, Didier Merlin, Emilie Viennois, Adani Pujada
Publikováno v: NPJ Biofilms and Microbiomes
npj Biofilms and Microbiomes, Vol 6, Iss 1, Pp 1-13 (2020)
npj Biofilms and Microbiomes
Numerous studies of knockout mice find impacts on microbiota composition that influence host phenotype. However, such differences can vanish when KO mice are compared directly to WT littermates, suggesting these differences do not reflect the genetic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f63cb32d88bca4f2125a3bd82e4ee4
http://europepmc.org/articles/PMC7374158
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4
Matrix metalloproteinase MMP9 maintains epithelial barrier function and preserves mucosal lining in colitis associated cancer
Autor: Timothy L. Denning, Tien Anh Bui, Aashka Patel, Pallavi Garg, Yuchen Zhang, Zhan Zhang, Lewins Walter, Adani Pujada
Publikováno v: Oncotarget
// Adani Pujada 1 , Lewins Walter 1 , Aashka Patel 2 , Tien Anh Bui 2 , Zhan Zhang 1 , Yuchen Zhang 1 , Timothy Luke Denning 1 and Pallavi Garg 1 1 Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA 2 Department of Biology,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd19e9d21c86fdb8482d0dba3ac42e59
https://doi.org/10.18632/oncotarget.21841
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6
Role of Notch1 in acute colitis and colitis associated cancer
Autor: Alcala, Adani Pujada
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that causes chronic inflammation and ulcers affecting the innermost layer of the colon. Almost 1 million people suffer from UC in the United States. UC patients have an increased risk of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f05f71273c866cbfa48f3481063a613
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7
Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis
Autor: Adani Pujada, Vincent W. Yang, Agnieszka B. Bialkowska, Hamed Laroui, Lewins Walter, Noopur Bhatnagar, Pallavi Garg
Publikováno v: Oncotarget
Colitis associated cancer (CAC) is chronic inflammation driven colon cancer, prevalent among individuals with Inflammatory Bowel Disease. Matrix-metalloproteinase (MMP9) is one of the essential regulators of extra cellular matrix components. We have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7293c25046bdfd5369ce65aef368c9b6
http://europepmc.org/articles/PMC5352126
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8
Silencing of matrix metalloproteinase MMP9 nurtures tumor microenvironment in chronic inflammation driven colon cancer
Autor: Hamed Laroui, Brandon Anh Canup, Tien Anh Bui, Adani Pujada, Pallavi Garg, Timothy L. Denning, Lewins Walter
Publikováno v: The FASEB Journal. 32
Introduction Chronic inflammation nurtures tumor microenvironment due to the release of various biomolecules such as cytokines, chemokines and growth factors which are the first response of the cel...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10a667cdcff2645f484d73b1f9d9bd11
https://doi.org/10.1096/fasebj.2018.32.1_supplement.610.4
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9
Function, Regulation, and Pathophysiological Relevance of the POT Superfamily, Specifically PepT1 in Inflammatory Bowel Disease
Autor: Emilie Viennois, Didier Merlin, Adani Pujada, Jane Zen
Publikováno v: Comprehensive Physiology
Mammalian members of the proton-coupled oligopeptide transporter family are integral membrane proteins that mediate the cellular uptake of di/tripeptides and peptide-like drugs and couple substrate translocation to the movement of H+ , with the trans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3968a2137a4a872ce9d20905fdce1437
https://europepmc.org/articles/PMC7188079/
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