Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages.

Autor: Szyszka TN; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia.; The University of Sydney Nano Institute, The University of Sydney, Camperdown, NSW 2006, Australia., Andreas MP; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109., Lie F; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia., Miller LM; Chemistry Department, Indiana University, Bloomington, IN 47405., Adamson LSR; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia., Fatehi F; Department of Mathematics, University of York, York YO10 5DD, United Kingdom.; York Cross-Disciplinary Centre for Systems Analysis, University of York, York YO10 5DD, United Kingdom., Twarock R; Department of Mathematics, University of York, York YO10 5DD, United Kingdom.; York Cross-Disciplinary Centre for Systems Analysis, University of York, York YO10 5DD, United Kingdom.; Department of Biology, University of York, York YO10 5DD, United Kingdom., Draper BE; Megadalton Solutions Inc., Bloomington, IN 47401., Jarrold MF; Chemistry Department, Indiana University, Bloomington, IN 47405., Giessen TW; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109., Lau YH; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia.; The University of Sydney Nano Institute, The University of Sydney, Camperdown, NSW 2006, Australia.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 May 14; Vol. 121 (20), pp. e2321260121. Date of Electronic Publication: 2024 May 09.

Pore structure controls stability and molecular flux in engineered protein cages.

Autor: Adamson LSR; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia.; CSIRO Future Science Platform in Synthetic Biology, Commonwealth Scientific and Industrial Research Organisation (CSIRO), 41 Boggo Road, Dutton Park, QLD 4102, Australia., Tasneem N; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia., Andreas MP; Department of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA., Close W; Australian Centre for Microscopy and Microanalysis, The University of Sydney, Camperdown, NSW 2006, Australia., Jenner EN; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia., Szyszka TN; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia., Young R; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia., Cheah LC; CSIRO Future Science Platform in Synthetic Biology, Commonwealth Scientific and Industrial Research Organisation (CSIRO), 41 Boggo Road, Dutton Park, QLD 4102, Australia.; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia., Norman A; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia.; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, Camperdown, NSW 2006, Australia., MacDermott-Opeskin HI; Research School of Chemistry, The Australian National University, Canberra, ACT 2601, Australia., O'Mara ML; Research School of Chemistry, The Australian National University, Canberra, ACT 2601, Australia., Sainsbury F; CSIRO Future Science Platform in Synthetic Biology, Commonwealth Scientific and Industrial Research Organisation (CSIRO), 41 Boggo Road, Dutton Park, QLD 4102, Australia.; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia.; Centre for Cell Factories and Biopolymers, Griffith Institute for Drug Discovery, Griffith University, Nathan, QLD 4111, Australia., Giessen TW; Department of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA., Lau YH; School of Chemistry, The University of Sydney, Camperdown, NSW 2006, Australia.; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, Camperdown, NSW 2006, Australia.; The University of Sydney Nano Institute, The University of Sydney, Campderdown, NSW 2006, Australia.

Publikováno v: Science advances [Sci Adv] 2022 Feb 04; Vol. 8 (5), pp. eabl7346. Date of Electronic Publication: 2022 Feb 04.