Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Adamo Valle"'
Autor:
Emilia Amengual-Cladera, Pere Miquel Morla-Barcelo, Andrea Morán-Costoya, Jorge Sastre-Serra, Daniel Gabriel Pons, Adamo Valle, Pilar Roca, Mercedes Nadal-Serrano
Publikováno v:
Biology, Vol 13, Iss 5, p 302 (2024)
Metformin, a widely used anti-diabetic drug, has garnered attention for its potential in cancer management, particularly in breast and colorectal cancer. It is established that metformin reduces mitochondrial respiration, but its specific molecular t
Externí odkaz:
https://doaj.org/article/e392b798743a44399db4ec0c4ab687ed
Autor:
Ester Kalef-Ezra, Fred Jonathan Edzeamey, Adamo Valle, Hassan Khonsari, Paula Kleine, Carlo Oggianu, Sahar Al-Mahdawi, Mark A. Pook, Sara Anjomani Virmouni
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionFriedreich’s ataxia (FRDA) is an inherited recessive neurodegenerative disorder caused by a homozygous guanine-adenine-adenine (GAA) repeat expansion within intron 1 of the FXN gene, which encodes the essential mitochondrial protein fra
Externí odkaz:
https://doaj.org/article/536964334c104f74840ef5dd71a79726
Autor:
Mursal Sherzai, Adamo Valle, Nicholas Perry, Ester Kalef-Ezra, Sahar Al-Mahdawi, Mark Pook, Sara Anjomani Virmouni
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Friedreich’s ataxia (FRDA) is a progressive neurodegenerative disorder caused by a homozygous GAA repeat expansion mutation in intron 1 of the frataxin gene (FXN), which instigates reduced transcription. As a consequence, reduced levels of frataxin
Externí odkaz:
https://doaj.org/article/1468f661eccb4df3ac3bbd6f101a879e
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 1, Pp 221-232 (2015)
Background/Aims: Large-scale epidemiological studies support a correlation between obesity and breast cancer in postmenopausal women. Circulating leptin levels are increased in obese and it has been suggested to play a significant role in mammary tum
Externí odkaz:
https://doaj.org/article/da7dca110b2f4115b977c96fa09a0ddb
Autor:
Miquel Sbert-Roig, Andrea Morán-Costoya, Ana M. Proenza, Bel M. Galmés-Pascual, Magdalena Gianotti, Adamo Valle, Isabel Lladó, Melanie Raquel Martínez-Cignoni, Marco Bauzá-Thorbrügge
Publikováno v:
Free Radical Biology and Medicine. 150:148-160
The prevalence and severity of nonalcoholic fatty liver disease (NAFLD) is higher in men and postmenopausal women compared to premenopausal women, suggesting a protective role for ovarian hormones. Diet-induced obesity and fatty acids surplus promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b860048a6f4c3716f498f8c73d1a89bb
https://doi.org/10.1016/j.freeradbiomed.2020.02.016
https://doi.org/10.1016/j.freeradbiomed.2020.02.016
Autor:
Agusti Gonzalez Vicens, Melanie Raquel Martínez-Cignoni, Isabel Lladó, Magdalena Gianotti, Adamo Valle, Andrea Moran Costoya, Ana Maria Proenza
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 13573, p 13573 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13573
International Journal of Molecular Sciences, Vol 22, Iss 13573, p 13573 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13573
It has been reported that 17β-estradiol (E2) can exert beneficial effects against the development of obesity, providing women with a healthier metabolic profile and conferring cardiovascular protection. However, a growing body of evidence questions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f13f81367e71ca5a83fd9805727de6
https://pubmed.ncbi.nlm.nih.gov/34948369
https://pubmed.ncbi.nlm.nih.gov/34948369
Autor:
Sara Anjomani-Virmouni, Clare M. Isacke, Zoltan Takats, George Poulogiannis, Adamo Valle, Aurelien Tripp, A van Weverwijk, Paolo Inglese, Robert C. Glen, Nikolaos Koundouros, Evdoxia Karali, Jeremy K. Nicholson, R Filipe-Soares, G Elder
Publikováno v:
The Journal of Pathology. 248:S1-S23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca0ab3098417582e030ec1a792cb4e3
https://doi.org/10.1002/path.5276
https://doi.org/10.1002/path.5276
Publikováno v:
Antioxidantsredox signaling. 35(9)
Significance: Nonalcoholic fatty liver disease (NAFLD) is a hepatic and systemic disorder with a complex multifactorial pathogenesis. Owing to the rising incidence of obesity and diabetes mellitus, the prevalence of NAFLD and its impact on global hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0e07f46340e88d05c778e3df4a192d
https://pubmed.ncbi.nlm.nih.gov/33736456
https://pubmed.ncbi.nlm.nih.gov/33736456
Autor:
Robert C. Glen, Maria Luisa Dória, Paolo Inglese, Jeremy K. Nicholson, George A. Elder, Nikos Koundouros, Clare M. Isacke, Aurelien Tripp, Nicholas J. S. Perry, Adamo Valle, George Poulogiannis, Renata F. Soares, David J. Magee, Adam L. Tyson, Zoltan Takats, Antoinette van Weverwijk, Evdoxia Karali, Sara Anjomani Virmouni
Publikováno v:
1611.e27
Cell
Cell, 2020, 181 (7), pp.1596-1611.e27. ⟨10.1016/j.cell.2020.05.053⟩
Clin Chem
Cell
Cell, 2020, 181 (7), pp.1596-1611.e27. ⟨10.1016/j.cell.2020.05.053⟩
Clin Chem
Summary Oncogenic transformation is associated with profound changes in cellular metabolism, but whether tracking these can improve disease stratification or influence therapy decision-making is largely unknown. Using the iKnife to sample the aerosol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fa130c7ff6980499d408b016c615ff
https://bura.brunel.ac.uk/handle/2438/21067
https://bura.brunel.ac.uk/handle/2438/21067
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:431-440
Background The polyphenol resveratrol (RSV) is found in the skin of red grapes and has been reported to exhibit anticancer properties. The antitumor effects of RSV in the gastrointestinal tract have gained considerable interest due to the high exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8671252040ad56fa0908cfaafbd17057
https://doi.org/10.1016/j.bbagen.2016.10.009
https://doi.org/10.1016/j.bbagen.2016.10.009