A Phase 1 dose-escalation study to evaluate safety, pharmacokinetics and pharmacodynamics of AsiDNA, a first-in-class DNA repair inhibitor, administered intravenously in patients with advanced solid tumours.

Autor: Le Tourneau C; Department of Drug Development and Innovation (D3i), Institut Curie, Paris and Saint-Cloud, France. christophe.letourneau@curie.fr., Delord JP; Institut Claudius Régaud, IUCT-Oncopole, Toulouse, France., Kotecki N; Medical Oncology Clinic, Institut Jules Bordet, Brussels, Belgium., Borcoman E; Department of Drug Development and Innovation (D3i), Institut Curie, Paris and Saint-Cloud, France., Gomez-Roca C; Institut Claudius Régaud, IUCT-Oncopole, Toulouse, France., Hescot S; Department of Drug Development and Innovation (D3i), Institut Curie, Paris and Saint-Cloud, France., Jungels C; Medical Oncology Clinic, Institut Jules Bordet, Brussels, Belgium., Vincent-Salomon A; Department of Tumor Biology, Institut Curie, Paris, France., Cockenpot V; Department of Tumor Biology, Institut Curie, Paris, France., Eberst L; Medical Oncology, Centre Léon Bérard, Lyon, France., Molé A; Clinical Department, Onxeo, Paris, France., Jdey W; Scientific Department, Onxeo, Paris, France., Bono F; Scientific Department, Onxeo, Paris, France., Trochon-Joseph V; Scientific Department, Onxeo, Paris, France., Toussaint H; Scientific Department, Onxeo, Paris, France., Zandanel C; Scientific Department, Onxeo, Paris, France., Adamiec O; Clinical Department, Onxeo, Paris, France., de Beaumont O; Clinical Department, Onxeo, Paris, France., Cassier PA; Medical Oncology, Centre Léon Bérard, Lyon, France.

Publikováno v: British journal of cancer [Br J Cancer] 2020 Nov; Vol. 123 (10), pp. 1481-1489. Date of Electronic Publication: 2020 Aug 25.

Increased metformin-associated lactic acidosis: a reality?

Autor: Sujol, G., Adamiec, O., Philibert, C., Pinzani, Véronique, Bengler, C., Hillaire-Buys, Dominique, Blayac, Jean-pierre

Publikováno v: Increased metformin-associated lactic acidosis
13ème congrés annuel de la société française de pharmacologie, 76ème congrès annuel de la société de physiologie, 15-17 Avril 2009, Marseille, France
13ème congrés annuel de la société française de pharmacologie, 76ème congrès annuel de la société de physiologie, 15-17 Avril 2009, Marseille, France, 2009, Marseille, France

Résumé de la communication accessible dans le Fundamental & Clinical Pharmacology, n°23, supplément 1, 2009, p.47; International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::16ad85bb66084242d845d7a8f96ef601
https://hal.archives-ouvertes.fr/hal-03074401

How ten-years of reirradiation for paediatric high-grade glioma may shed light on first line treatment.

Autor: Massimino, Maura, Vennarini, Sabina, Barretta, Francesco, Colombo, Francesca, Antonelli, Manila, Pollo, Bianca, Pignoli, Emanuele, Pecori, Emilia, Alessandro, Ombretta, Schiavello, Elisabetta, Boschetti, Luna, Podda, Marta, Puma, Nadia, Gattuso, Giovanna, Sironi, Giovanna, Barzanò, Elena, Nigro, Olga, Bergamaschi, Luca, Chiaravalli, Stefano, Luksch, Roberto

Publikováno v: Journal of Neuro-Oncology; Sep2022, Vol. 159 Issue 2, p437-445, 9p

Mounting-induced strains in red-emitting (Al)InGaP laser diodes tuned by pressure.

Autor: Piechal, Bernard¹ bernard@unipress.waw.pl, Tomm, Jens W.² tomm@mbi-berlin.de, Bercha, Artem¹, Trzeciakowski, Witold¹, Reufer, Martin³ Martin.Reufer@osram-os.com, Gomez-Iglesias, Alvaro³

Publikováno v: Applied Physics A: Materials Science & Processing. Oct2009, Vol. 97 Issue 1, p179-184. 6p. 1 Chart, 3 Graphs.

Combination DNA Damage Response (DDR) Inhibitors to Overcome Drug Resistance in Ovarian Cancer.

Autor: Nasioudis D; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, PA, 19104, USA., George EM; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, PA, 19104, USA., Xu H; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, PA, 19104, USA., Kim H; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, PA, 19104, USA., Simpkins F; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Perelman School of Medicine, Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, PA, 19104, USA. fiona.simpkins@pennmedicine.upenn.edu.

Publikováno v: Cancer treatment and research [Cancer Treat Res] 2023; Vol. 186, pp. 189-206.