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Enhanced Expression of the L1R Gene of Vaccinia Virus by the tPA Signal Sequence Inserted in a Fowlpox-Based Recombinant Vaccine.

Autor: Radaelli, Antonia, Zanotto, Carlo, Brambilla, Chiara, Adami, Tommaso, De Giuli Morghen, Carlo

Publikováno v: Vaccines; Oct2024, Vol. 12 Issue 10, p1115, 12p

Different immunogens and prime-boost vaccination strategies affect the efficacy of recombinant candidate vaccines against pathogenic orthopoxviruses.

Autor: Radaelli A; Department of Medical Biotechnologies and Translational Medicine, University of Milan, via Vanvitelli 32, Milan, 20129, Italy.; Faculty of Pharmacy, Catholic University 'Our Lady of Good Counsel', Rr. Dritan Hoxha, 123, Tirana, Albania., Zanotto C; Department of Medical Biotechnologies and Translational Medicine, University of Milan, via Vanvitelli 32, Milan, 20129, Italy. carlo.zanotto@unimi.it.; Laboratory of Molecular Virology and Recombinant Vaccine Development, Department of Medical Biotechnologies and Translational Medicine, University of Milan, Via Vanvitelli, 32, Milan, 20129, Italy. carlo.zanotto@unimi.it., Brambilla C; Department of Medical Biotechnologies and Translational Medicine, University of Milan, via Vanvitelli 32, Milan, 20129, Italy., Adami T; Department of Medical Biotechnologies and Translational Medicine, University of Milan, via Vanvitelli 32, Milan, 20129, Italy., Paolini F; UOSD Tumor Immunology and Immunotherapy, HPV UNIT, IRCCS Regina Elena National Cancer Institute, via Chianesi, 53, Rome, 00144, Italy., Venuti A; UOSD Tumor Immunology and Immunotherapy, HPV UNIT, IRCCS Regina Elena National Cancer Institute, via Chianesi, 53, Rome, 00144, Italy., Manuka A; Faculty of Pharmacy, Catholic University 'Our Lady of Good Counsel', Rr. Dritan Hoxha, 123, Tirana, Albania., Mehmeti I; Faculty of Pharmacy, Catholic University 'Our Lady of Good Counsel', Rr. Dritan Hoxha, 123, Tirana, Albania., De Giuli Morghen C; Faculty of Pharmacy, Catholic University 'Our Lady of Good Counsel', Rr. Dritan Hoxha, 123, Tirana, Albania.

Publikováno v: Virology journal [Virol J] 2024 Nov 07; Vol. 21 (1), pp. 282. Date of Electronic Publication: 2024 Nov 07.