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pro vyhledávání: '"Adamaki M"'
Glucocorticoids (GCs) are still first-line drugs for the treatment of childhood acute lymphoblastic leukemia (ALL). Prednisolone is a corticosteroid and one of the most important agents in the treatment of ALL. We report here a study of Prednisolone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::2490fb2babca997905b30aebf7c43c5d
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077218
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077218
Background: Resistance to glucocorticoid (GC)-induced apoptosis in Acute Lympho-blastic Leukemia (ALL), is considered one of the major prognostic factors for the disease. Predniso-lone is a corticosteroid and one of the most important agents in the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::7b76443e77e454123acda86cfd863c1f
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3121587
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3121587
Cytokines are pivotal mediators of the immune response, and their coordinated expression protects host tissue from excessive damage and oxidant stress. Nevertheless, the development of lung pathology, including asthma, chronic obstructive pulmonary d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::416e9b339fa11ba920c28ca195deae2c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3021384
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3021384
The AML1 (acute myeloid leukemia 1) gene, a necessary prerequisite of embryonic hematopoiesis and a critical regulator of normal hematopoietic development, is one of the most frequently mutated genes in human leukemia, involving over 50 chromosome tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::3fa569f9b784312c208717cbfa8894cf
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087188
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087188
Homeobox (HOX) genes are a superfamily of highly conserved genes with essential functions in many aspects of mammalian development. Their expression is tightly regulated throughout the duration of definitive hematopoiesis, so the pathogenetic mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::934a3058fa073d2d987dba7f8052403e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087286
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087286
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Homeobox genes HOXA9 and MEIS1 are evolutionarily conserved transcription factors with essential roles in both hematopoiesis and leukemogenesis. They act as dominant cooperating oncoproteins that cause acute leukemias bearing MLL translocations and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::fbfb864c259dbc148ab2da24d754ef69
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088222
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088222
Recently it was discovered that a transient activation of transcription factor NF-κB can give cells properties essential for invasiveness and cancer initiating potential. In contrast, most oncogenes to date were characterized on the basis of mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::e49ce7b0359a072e8f4d03d99cbb968e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3002797
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3002797