Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Adam10 protein, mouse"'
Autor:
Javier Rueda-Carrasco, Paula Garcia-Esparcia, Inmaculada Crespo, José A. Esteban, Juan Fortea, Pilar Esteve, José M. Valpuesta, Alberto Lleó, Guadalupe Pereyra, Estrella Gómez-Tortosa, María Jesús Martín-Bermejo, Isidro Ferrer, Mercedes Domínguez, Jonathan E. Draffin, Paola Bovolenta, Inmaculada Moreno, Daniel Alcolea, Alberto Rábano, Ester Aso, África Sandonís, Michael T. Heneka, María Inés Mateo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature reviews / Neuroscience 22(8), 1258-1268 (2019). doi:10.1038/s41593-019-0432-1
NATURE NEUROSCIENCE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Nature reviews / Neuroscience 22(8), 1258-1268 (2019). doi:10.1038/s41593-019-0432-1
NATURE NEUROSCIENCE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
The deposition of aggregated amyloid-β peptides derived from the pro-amyloidogenic processing of the amyloid precurson protein (APP) into characteristic amyloid plaques (APs) is distinctive to Alzheimer’s disease (AD). Alternative APP processing v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a0f9a5692c67f30d39b2f9105c61ff
http://hdl.handle.net/10261/193936
http://hdl.handle.net/10261/193936
Autor:
Paolo Canevazzi, Stefan F. Lichtenthaler, Regina Feederle, Thomas Misgeld, Hung-En Hsia, Carla Taveggia, Alessio Colombo, Mengzhe Wang, Monika S. Brill, Peer-Hendrik Kuhn
Publikováno v:
The EMBO journal 37(7), e97390 (2018). doi:10.15252/embj.201797390
EMBO J. 37:e97390 (2018)
EMBO J. 37:e97390 (2018)
Death receptor 6 (DR6) is an orphan member of the TNF receptor superfamily and controls cell death and differentiation in a cell‐autonomous manner in different cell types. Here, we report an additional non‐cell‐autonomous function for DR6 in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4a3313130430317623b1d124db672b
https://doi.org/10.15252/embj.201797390
https://doi.org/10.15252/embj.201797390
Autor:
Peter J. Dempsey, Alessio Colombo, Huanhuan Wang, Howard C. Crawford, Richard M. Page, Stefan F. Lichtenthaler, Peer-Hendrik Kuhn, Elisabeth Kremmer
Publikováno v:
Neurobiology of Disease, Vol 49, Iss, Pp 137-147 (2013)
Neurobiology of disease 49, 137-147 (2013). doi:10.1016/j.nbd.2012.08.011
Neurobiology of disease 49, 137-147 (2013). doi:10.1016/j.nbd.2012.08.011
Proteolytic cleavage of the amyloid precursor protein (APP) by the two proteases α- and β-secretases controls the generation of the amyloid β peptide (Aβ), a key player in Alzheimer's disease pathogenesis. The α-secretase ADAM10 and the β-secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a210b18f7776118cd99ac65dfe680f
http://www.sciencedirect.com/science/article/pii/S0969996112002987
http://www.sciencedirect.com/science/article/pii/S0969996112002987
Autor:
Benjamin Schusser, Michaela Schweizer, Daniela Dreymueller, Stefan F. Lichtenthaler, Dirk Montag, Julia Herber, Sebastian Wetzel, Paul Saftig, Peer-Hendrik Kuhn, Elisabeth Kremmer, Andreas Ludwig, Ulrike Müller, Stefan Bräse, Alessio Colombo, Ute Schepers
Publikováno v:
eLife, Vol 5 (2016)
eLife 5, e12748 (2016). doi:10.7554/eLife.12748
eLife, 5 (JANUARY2016), e12748
eLife, 5:e12748
eLife 5:e12748 (2016)
eLife
eLife 5, e12748 (2016). doi:10.7554/eLife.12748
eLife, 5 (JANUARY2016), e12748
eLife, 5:e12748
eLife 5:e12748 (2016)
eLife
Metzincin metalloproteases have major roles in intercellular communication by modulating the function of membrane proteins. One of the proteases is the a-disintegrin-and-metalloprotease 10 (ADAM10) which acts as alpha-secretase of the Alzheimer's dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191b399eaeb467521bf601203b436eb5
https://elifesciences.org/articles/12748
https://elifesciences.org/articles/12748
Publikováno v:
Journal of neurochemistry 128(2), 206-209 (2013). doi:10.1111/jnc.12514
J Neurochem
J Neurochem
EphrinA/EphA-dependent axon repulsion is crucial for synaptic targeting in developing neurons but downstream molecular mechanisms remain obscure. Here, it is shown that ephrinA5/EphA3 triggers proteolysis of the neural cell adhesion molecule (NCAM) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67328d0043fb5375e3312d523491882e
https://pub.dzne.de/record/137260
https://pub.dzne.de/record/137260
Autor:
Peer-Hendrik Kuhn, Huanhuan Wang, Elisabeth Kremmer, Steffen Roßner, Bastian Dislich, Stefan F. Lichtenthaler, Joachim W. Ellwart, Ulrike Zeitschel, Alessio Colombo
Publikováno v:
EMBO J. 29, 3020-3032 (2010)
The EMBO journal 29(17), 3020-3032 (2010). doi:10.1038/emboj.2010.167
The EMBO journal 29(17), 3020-3032 (2010). doi:10.1038/emboj.2010.167
The amyloid precursor protein (APP) undergoes constitutive shedding by a protease activity called alpha-secretase. This is considered an important mechanism preventing the generation of the Alzheimer's disease amyloid-beta peptide (Abeta). alpha-Secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74366ab201c168b378ab9bae33bfa279
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=6013
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=6013