Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Adam Z Rosenthal"'
Publikováno v:
eLife, Vol 7 (2018)
Individual microbial species are known to occupy distinct metabolic niches within multi-species communities. However, it has remained largely unclear whether metabolic specialization can similarly occur within a clonal bacterial population. More spec
Externí odkaz:
https://doaj.org/article/5a7d3a57429a436d9e9cc1ed8c4e19af
Autor:
Melanie A. Brennan, Adam Z. Rosenthal
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Clonal bacterial populations exhibit various forms of heterogeneity, including co-occurrence of cells with different morphological traits, biochemical properties, and gene expression profiles. This heterogeneity is prevalent in a variety of environme
Externí odkaz:
https://doaj.org/article/05885f24bbeb4c30b5ca20fd2f63ea33
Autor:
Ryan McNulty, Duluxan Sritharan, Seong Ho Pahng, Jeffrey P. Meisch, Shichen Liu, Melanie A. Brennan, Gerda Saxer, Sahand Hormoz, Adam Z. Rosenthal
Publikováno v:
Nature Microbiology. 8:934-945
Clonal bacterial populations rely on transcriptional variation across individual cells to produce specialized states that increase fitness. Understanding all cell states requires studying isogenic bacterial populations at the single-cell level. Here
Autor:
Amrit P. Singh, Frank Schmitz, Adam Z. Rosenthal, Madhav V. Dhodapkar, Antje Hoering, Daisy Alapat, Yan Ren, Maurizio Zangari, Kelsie Smith, Samuel A. Danziger, Jake Gockley, Andrew Dervan, Alexander V. Ratushny, Mark McConnell, Robert M. Hershberg, Suzana Couto, Brian A Walker, Faith E. Davies, Alison Fitch, Wilbert B. Copeland, Gareth J. Morgan, Bart Barlogie, Phil Farmer, David J. Reiss, Brian Fox, Mary H. Young, Frits van Rhee, Cody Ashby, Katie Newhall, Nathan Petty, Michael A Bauer, Robert Z. Orlowski, Matthew Trotter
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
Background The tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcome, including in multiple myeloma (MM). However, most myeloma microenvironment studies have been based on bone marrow (BM) aspirates, w
Autor:
Faith E. Davies, Brian A Walker, Antje Hoering, Philip Farmer, Bart Barlogie, Frits van Rhee, Sharmilan Thanendrarajan, Carolina Schinke, Yan Wang, Adam Z. Rosenthal, Gareth J. Morgan, Eileen M Boyle, Sarah K. Johnson, Christopher P. Wardell, Michael A Bauer, Cody Ashby, Maurizio Zangari, Michael E. Rutherford
Publikováno v:
British journal of haematologyReferences. 195(2)
Autor:
Adam Z. Rosenthal, Melanie A Brennan
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology
Frontiers in Microbiology
Clonal bacterial populations exhibit various forms of heterogeneity, including co-occurrence of cells with different morphological traits, biochemical properties, and gene expression profiles. This heterogeneity is prevalent in a variety of environme
Autor:
Sarah K. Johnson, Faith E. Davies, Frits van Rhee, Adam Z. Rosenthal, Eileen M Boyle, Carolina Schinke, Sharmilan Thanendrarajan, Madhav V. Dhodapkar, Antje Hoering, Hussein Ghamlouch, Christopher P. Wardell, Brian A Walker, Bart Barlogie, Cody Ashby, Gareth J. Morgan, Yan Wang, Michael E. Rutherford, Maurizio Zangari, Phillip Farmer, Yubao Wang, Michael A Bauer
Publikováno v:
Leukemia. 36(2)
Sequencing studies have shed some light on the pathogenesis of progression from smouldering multiple myeloma (SMM) and symptomatic multiple myeloma (MM). Given the scarcity of smouldering samples, little data are available to determine which translat
Clonal bacterial populations rely on transcriptional variation to differentiate into specialized cell states that increase the community’s fitness. Such heterogeneous gene expression is implicated in many fundamental microbial processes including s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f340fd12ed111508b02a6c05fd47e78e
https://doi.org/10.21203/rs.3.rs-322406/v1
https://doi.org/10.21203/rs.3.rs-322406/v1
Clonal bacterial populations rely on transcriptional variation to differentiate into specialized cell states that increase the community’s fitness. Such heterogeneous gene expression is implicated in many fundamental microbial processes including s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::352d998c43fc55dc040dce8f738414b2
https://doi.org/10.1101/2021.03.10.434868
https://doi.org/10.1101/2021.03.10.434868
Publikováno v:
mBio, Vol 4, Iss 6 (2013)
ABSTRACT When prokaryotic cells acquire mutations, encounter translation-inhibiting substances, or experience adverse environmental conditions that limit their ability to synthesize proteins, transcription can become uncoupled from translation. Such
Externí odkaz:
https://doaj.org/article/5eed56bb76fd4c2f8363fd8b2a1952dc