Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Adam Wroński"'
Autor:
Adam Wroński, Agnieszka Gęgotek, Tiago Conde, Maria Rosário Domingues, Pedro Domingues, Elżbieta Skrzydlewska
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1236 (2024)
Psoriasis is characterized by excessive exfoliation of the epidermal layer due to enhanced pro-inflammatory signaling and hyperproliferation of keratinocytes, further modulated by UV-based anti-psoriatic treatments. Consequently, this study aimed to
Externí odkaz:
https://doaj.org/article/7aefe0d070494f37b9fb30c55e106518
Autor:
Adam Wroński, Iwona Jarocka-Karpowicz, Arkadiusz Surażyński, Agnieszka Gęgotek, Neven Zarkovic, Elżbieta Skrzydlewska
Publikováno v:
Cells, Vol 13, Iss 11, p 965 (2024)
UVA exposure disturbs the metabolism of skin cells, often inducing oxidative stress and inflammation. Therefore, there is a need for bioactive compounds that limit such consequences without causing undesirable side effects. The aim of this study was
Externí odkaz:
https://doaj.org/article/9a522cb426b3409f8d516cf3f06ab0f7
Publikováno v:
Redox Biology, Vol 63, Iss , Pp 102729- (2023)
Psoriasis, one of the most frequent immune-mediated skin diseases, is manifested by numerous psoriatic lessons on the skin caused by excessive proliferation and keratinization of epidermal cells. These disorders of keratinocyte metabolism are caused
Externí odkaz:
https://doaj.org/article/10b448a5814342cd869208d99dc86d8d
Publikováno v:
Molecules, Vol 28, Iss 3, p 1192 (2023)
Phytocannabinoids are naturally occurring compounds, the main source of which is Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors, they affect ROS and pro-inflammatory cytokines levels and modify the effectiven
Externí odkaz:
https://doaj.org/article/9611315031024610940f26f30472990b
Autor:
Barbara Szachowicz-Petelska, Wojciech Łuczaj, Adam Wroński, Anna Jastrząb, Izabela Dobrzyńska
Publikováno v:
Membranes, Vol 11, Iss 2, p 111 (2021)
The development of psoriasis is accompanied by oxidative stress, which can modify the components of skin cells. Therefore, the aim of this study was to evaluate the effect of cannabidiol (CBD), an antioxidant and anti-inflammatory phytocannabinoid, o
Externí odkaz:
https://doaj.org/article/af9198c2b7fc42ab8cda35355f639b9e
Autor:
Iwona Jarocka-Karpowicz, Michał Biernacki, Adam Wroński, Agnieszka Gęgotek, Elżbieta Skrzydlewska
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 367 (2020)
Psoriasis is a chronic inflammatory skin disease characterized by dysregulated keratinocyte differentiation, but oxidative stress also plays an important role in the pathogenesis of this disease. Here, we examined the effect of cannabidiol (CBD), a p
Externí odkaz:
https://doaj.org/article/a9679233355a4cbc819cc9cff8745856
Publikováno v:
Molecules, Vol 25, Iss 3, p 630 (2020)
Ceramides are important lipid metabolites for primal skin functions. There is increasing evidence that alteration of the profile and metabolism of ceramides is associated with skin diseases, such as psoriasis vulgaris. Most studies have reported alte
Externí odkaz:
https://doaj.org/article/bb000ff87af947b89de25daff3123aff
Autor:
Ewa Ambrożewicz, Piotr Wójcik, Adam Wroński, Wojciech Łuczaj, Anna Jastrząb, Neven Žarković, Elżbieta Skrzydlewska
Publikováno v:
Cells, Vol 7, Iss 10, p 159 (2018)
Inflammatory granulocytes are characterized by an oxidative burst, which may promote oxidative stress and lipid modification both in affected tissues and on a systemic level. On the other hand, redox signaling involving lipid peroxidation products ac
Externí odkaz:
https://doaj.org/article/fa23af2e19284115ab414757e594f9c0
Autor:
Adam Wroński, Piotr Wójcik
Publikováno v:
International journal of molecular sciences. 23(20)
Psoriasis is the most common autoimmune disease, yet its pathophysiology is not fully understood. It is now believed that psoriasis is caused by the increased activation of immune cells, especially Th1 lymphocytes. However, in psoriasis, immune cells
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
The development of psoriasis is associated with the consequences of oxidative stress and inflammation leading to metabolic changes locally, in the skin cells, and systemically, in the blood. Therefore, the aim of this study was to analyze the effect