Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Adam W. Hantman"'
Autor:
Kaushik J. Lakshminarasimhan, Marjorie Xie, Jeremy D. Cohen, Britton A. Sauerbrei, Adam W. Hantman, Ashok Litwin-Kumar, Sean Escola
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114059- (2024)
Summary: Thalamocortical loops have a central role in cognition and motor control, but precisely how they contribute to these processes is unclear. Recent studies showing evidence of plasticity in thalamocortical synapses indicate a role for the thal
Externí odkaz:
https://doaj.org/article/435f8ab3e4d44e5eac6aa5ce58b47b2a
Publikováno v:
Cell Reports, Vol 27, Iss 9, Pp 2620-2635.e4 (2019)
Summary: Coordinated motor behaviors depend on feedback communication between peripheral sensory systems and central circuits in the brain and spinal cord. Relay of muscle- and tendon-derived sensory information to the CNS is facilitated by functiona
Externí odkaz:
https://doaj.org/article/07fe1a070cd54ac5a2e942684dcf0b89
Autor:
Jian-Zhong Guo, Britton A Sauerbrei, Jeremy D Cohen, Matteo Mischiati, Austin R Graves, Ferruccio Pisanello, Kristin M Branson, Adam W Hantman
Publikováno v:
eLife, Vol 10 (2021)
To control reaching, the nervous system must generate large changes in muscle activation to drive the limb toward the target, and must also make smaller adjustments for precise and accurate behavior. Motor cortex controls the arm through projections
Externí odkaz:
https://doaj.org/article/d5f60a80134c41c18955aeabd07e2d87
Autor:
Ken Sugino, Erin Clark, Anton Schulmann, Yasuyuki Shima, Lihua Wang, David L Hunt, Bryan M Hooks, Dimitri Tränkner, Jayaram Chandrashekar, Serge Picard, Andrew L Lemire, Nelson Spruston, Adam W Hantman, Sacha B Nelson
Publikováno v:
eLife, Vol 8 (2019)
Understanding the principles governing neuronal diversity is a fundamental goal for neuroscience. Here, we provide an anatomical and transcriptomic database of nearly 200 genetically identified cell populations. By separately analyzing the robustness
Externí odkaz:
https://doaj.org/article/4d2dcd9a16ad4c25bad67f96be08c705
Autor:
Jian-Zhong Guo, Austin R Graves, Wendy W Guo, Jihong Zheng, Allen Lee, Juan Rodríguez-González, Nuo Li, John J Macklin, James W Phillips, Brett D Mensh, Kristin M Branson, Adam W Hantman
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/5c86566ffac7461fb45c0a20ad009b45
Autor:
Simina M. Boca, Saivasudha Chalasani, Talia N. Lerner, Harry S. Xenias, Isabel Fan, Adam W. Hantman, Arin Pamukcu, Qiaoling Cui, Brianna L. Berceau, Elizabeth C. Augustine, C. Savio Chan
Publikováno v:
The Journal of Neuroscience. 40:7855-7876
The external globus pallidus (GPe) is a critical node within the basal ganglia circuit. Phasic changes in the activity of GPe neurons during movement and their alterations in Parkinson's disease (PD) argue that the GPe is important in motor control.
Autor:
Jian-Zhong Guo, Austin R Graves, Wendy W Guo, Jihong Zheng, Allen Lee, Juan Rodríguez-González, Nuo Li, John J Macklin, James W Phillips, Brett D Mensh, Kristin Branson, Adam W Hantman
Publikováno v:
eLife, Vol 4 (2015)
Mammalian cerebral cortex is accepted as being critical for voluntary motor control, but what functions depend on cortex is still unclear. Here we used rapid, reversible optogenetic inhibition to test the role of cortex during a head-fixed task in wh
Externí odkaz:
https://doaj.org/article/ca20b66a26f24c9f97fae52732de8723
Autor:
Jian-Zhong Guo, Britton A Sauerbrei, Jeremy D Cohen, Matteo Mischiati, Austin R Graves, Ferruccio Pisanello, Kristin M Branson, Adam W Hantman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a038164d0390b3f75c3fc1f9224df18b
https://doi.org/10.7554/elife.65906.sa2
https://doi.org/10.7554/elife.65906.sa2
Autor:
Brett D. Mensh, Joshua T. Dudman, Jayaram Chandrashekar, Johan Winnubst, Chenghao Liu, James W Phillips, Wyatt Korff, Erina Hara, Andrew L. Lemire, Brenda C Shields, Lihua Wang, Anton Schulmann, Adam W. Hantman, Vera Valakh, Sacha B. Nelson
Publikováno v:
Nature neuroscience
The thalamus is the central communication hub of the forebrain and provides the cerebral cortex with inputs from sensory organs, subcortical systems and the cortex itself. Multiple thalamic regions send convergent information to each cortical region,
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
Granule cells (GCs) in the cerebellar cortex are important for sparse encoding of afferent sensorimotor information. Modeling studies show that GCs can perform their function most effectively when they have four dendrites. Indeed, mature GCs have fou