Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Adam W. Beharry"'
Autor:
Daniel J Ryder, Sarah M Judge, Adam W Beharry, Charles L Farnsworth, Jeffrey C Silva, Andrew R Judge
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136247 (2015)
Skeletal muscle atrophy is a consequence of several physiological and pathophysiological conditions including muscle disuse, aging and diseases such as cancer and heart failure. In each of these conditions, the predominant mechanism contributing to t
Externí odkaz:
https://doaj.org/article/8afc89d02834430baa0666004235122e
Autor:
Adam W. Beharry, Leonardo F. Ferreira, Ira J. Smith, Andrew Judge, Donald G. Payan, Brandon M. Roberts, Guillermo Godinez, Todd Kinsella
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Respiratory dysfunction is prevalent in critically ill patients and can lead to adverse clinical outcomes, including respiratory failure and increased mortality. Respiratory muscles, which normally sustain respiration through inspiratory muscle contr
Autor:
Adam W. Beharry, Andrew Judge
Publikováno v:
Muscle & Nerve. 52:1098-1101
Histone deacetylase (HDAC) proteins, which counter the activity of histone acetyltransferases (HATs), are necessary for normal muscle atrophy in response to several pathophysiological conditions. Despite this, it remains unknown whether a common or u
Autor:
Jennifer S. Moylan, Adam W. Beharry, Bumsoo Ahn, Andrew Judge, Nikhil Patel, Mark R. Bonnell, Leonardo F. Ferreira, Philip D. Coblentz, Charles W. Hoopes
Publikováno v:
Frontiers in Physiology
Patients with heart failure (HF) have diaphragm abnormalities that contribute to disease morbidity and mortality. Studies in animals suggest that reactive oxygen species (ROS) cause diaphragm abnormalities in HF. However, the effects of HF on ROS sou
Autor:
Adam W, Beharry, Andrew R, Judge
Publikováno v:
Musclenerve. 52(6)
Histone deacetylase (HDAC) proteins, which counter the activity of histone acetyltransferases (HATs), are necessary for normal muscle atrophy in response to several pathophysiological conditions. Despite this, it remains unknown whether a common or u
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 309(5)
Patients with chronic heart failure (CHF) have dyspnea and exercise intolerance, which are caused in part by diaphragm abnormalities. Oxidants impair diaphragm contractile function, and CHF increases diaphragm oxidants. However, the specific source o
Autor:
Brandon M. Roberts, Andrew Judge, Leonardo F. Ferreira, Adam W. Beharry, Chia-Ling Wu, Susan C. Kandarian, Sarah M. Judge
Publikováno v:
BMC Cancer
Background Evidence from cachectic cancer patients and animal models of cancer cachexia supports the involvement of Forkhead box O (FoxO) transcription factors in driving cancer-induced skeletal muscle wasting. However, the genome-wide gene networks
Autor:
Brandon M. Roberts, Pooja B. Sandesara, Adam W. Beharry, Leonardo F. Ferreira, Sarah M. Senf, Andrew Judge
Publikováno v:
Journal of Cell Science.
The Forkhead boxO (FoxO) transcription factors are activated and necessary for the muscle atrophy during several pathophysiological conditions, including muscle disuse and cancer cachexia. Yet, the mechanisms which lead to FoxO activation are not wel
Autor:
Stephen E. Borst, Joshua F. Yarrow, Fan Ye, Christine F. Conover, Sarah M. Senf, Darren T. Beck, Andrew Judge, Joseph A. Bernardo, Adam W. Beharry, Heather H. Ross, Sean C. McCoy, Barbara K. Smith, Darryl F. Cannady
Publikováno v:
Steroids
Androgens regulate body composition and skeletal muscle mass in males, but the molecular mechanisms are not fully understood. Recently, we demonstrated that trenbolone (a potent synthetic testosterone analogue that is not a substrate for 5-alpha redu
Autor:
Stephen E. Borst, Hordur G. Kristinsson, Luke A. Beggs, Sally E. Johnson, Bryan P. Conrad, Fan Ye, Darren T. Beck, Joshua F. Yarrow, Andrew Judge, Jennifer E. Pingel, Paul A. Borsa, Sean C. McCoy, Christine F. Conover, Thomas J. Wronski, Mark D. Tillman, Heather H. Ross, Adam W. Beharry
Publikováno v:
The FASEB Journal. 27
Trenbolone (TREN), a potent testosterone analog, does not undergo 5[alpha]-reduction to the more potent metabolite dihydrotestosterone (DHT) and may produce androgenic effects without DHT-mediated ...