Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Adam W. Akerman"'
Autor:
Kyle C. Alexander, Carlton W. Anderson, Chris B. Agala, Panagiotis Tasoudis, Elizabeth N. Collins, Yiwen Ding, John W. Blackwell, Danielle E. Willcox, Behzad S. Farivar, Melina R. Kibbe, John S. Ikonomidis, Adam W. Akerman
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 6, p 1548 (2024)
Background: Thoracic aortic aneurysms (TAAs) associated with Marfan syndrome (MFS) are unique in that extracellular matrix metalloproteinase inducer (EMMPRIN) levels do not behave the way they do in other cardiovascular pathologies. EMMPRIN is shed i
Externí odkaz:
https://doaj.org/article/6fbe1bc30c754c68aea34c5d8916e3e2
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 3, p 818 (2024)
This review article presents an appraisal of pioneering technologies poised to revolutionize the diagnosis and management of aortic aneurysm disease, with a primary focus on the thoracic aorta while encompassing insights into abdominal manifestations
Externí odkaz:
https://doaj.org/article/93f6463f253d453b86a240208e0bc881
Autor:
Adam W. Akerman, Elizabeth N. Collins, Andrew R. Peterson, Lauren B. Collins, Jessica K. Harrison, Amari DeVaughn, Jaleel M. Townsend, Rebecca L. Vanbuskirk, Jessica Riopedre‐Maqueira, Ailet Reyes, Joyce E. Oh, Charles M. Raybuck, Jeffrey A. Jones, John S. Ikonomidis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
Background Thoracic aortic aneurysms (TAAs) occur because of abnormal remodeling of aortic extracellular matrix and are accompanied by the emergence of proteolytically active myofibroblasts. The microRNA miR‐133a regulates cellular phenotypes and i
Externí odkaz:
https://doaj.org/article/bba559186768485f8fb4ea7373e8752a
Autor:
Adam W. Akerman, Walker M. Blanding, Robert E. Stroud, Elizabeth K. Nadeau, Rupak Mukherjee, Jean Marie Ruddy, Michael R. Zile, John S. Ikonomidis, Jeffrey A. Jones
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 1 (2019)
Background Reduced miR‐133a was previously found to be associated with thoracic aortic (TA) dilation, as seen in aneurysm disease. Because wall tension increases with vessel diameter (Law of Laplace), this study tested the hypothesis that elevated
Externí odkaz:
https://doaj.org/article/5937d54013134b7f983beb23a4ce0a65
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery.
Autor:
Benjamin T. Ledford, Adam W. Akerman, Kui Sun, David C. Gillis, Jenna M. Weiss, Johnny Vang, Smaranda Willcox, Tristan D. Clemons, Hiroaki Sai, Ruomeng Qiu, Mark R. Karver, Jack D. Griffith, Nick D. Tsihlis, Samuel I. Stupp, John S. Ikonomidis, Melina R. Kibbe
Publikováno v:
ACS Nano
An abdominal aortic aneurysm (AAA) is a localized dilation of the aorta located in the abdomen that poses a severe risk of death when ruptured. The cause of AAA is not fully understood, but degradation of medial elastin due to elastolytic matrix meta
Autor:
J. Nathaniel Diehl, Amelia Ray, Lauren B. Collins, Andrew Peterson, Kyle C. Alexander, Jacob G. Boutros, John S. Ikonomidis, Adam W. Akerman
Publikováno v:
PLOS ONE. 18:e0284875
The following protocol describes our workflow for isolation and quantification of plasma extracellular vesicles (EVs). It requires limited sample volume so that the scientific value of specimens is maximized. These steps include isolation of vesicles
Autor:
Jessica Riopedre-Maqueira, Joyce E Oh, Adam W Akerman, Amari DeVaughn, Jessica K Harrison, Charles M Raybuck, Jaleel M Townsend, Elizabeth N Collins, John S. Ikonomidis, Jeffrey A. Jones, Lauren B Collins, Andrew R Peterson, Rebecca L Vanbuskirk, Ailet Reyes
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Thoracic aortic aneurysms (TAAs) occur because of abnormal remodeling of aortic extracellular matrix and are accompanied by the emergence of proteolytically active myofibroblasts. The microRNA miR‐133a regulates cellular phenotypes and i
Autor:
John S. Ikonomidis, Rupak Mukherjee, R. Amanda C. Larue, R. Tyler Grespin, Ryan W. Barrs, Jean Marie Ruddy, Lindsay T. McDonald, Adam W. Akerman, Jeffery A. Jones, Robert E. Stroud
Publikováno v:
Annals of Vascular Surgery. 46:193-204
Hypertension (HTN) has long been associated with abdominal aortic aneurysm (AAA) development, and these cardiovascular pathologies are biochemically characterized by elevated plasma levels of angiotensin II (AngII) as well as interleukin-6 (IL-6). A
Publikováno v:
JAMA Surgery. 156:264
Importance Although fluoroquinolones are commonly prescribed antibiotics in the US, recent international studies have shown an increased risk of aortic aneurysm and dissection after fluoroquinolone use, leading to US Food and Drug Administration warn