Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adam T. Piers"'
Autor:
Natalie Charitakis, Agus Salim, Adam T. Piers, Kevin I. Watt, Enzo R. Porrello, David A. Elliott, Mirana Ramialison
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Identifying spatially variable genes (SVGs) is a key step in the analysis of spatially resolved transcriptomics data. SVGs provide biological insights by defining transcriptomic differences within tissues, which was previously unachievable u
Externí odkaz:
https://doaj.org/article/1b4f8dd834724091bdaa2bce84d5993b
Autor:
Peter J. Houweling, Chantal A. Coles, Chrystal F. Tiong, Bridget Nielsen, Alison Graham, Penny McDonald, Annabelle Suter, Adam T. Piers, Robin Forbes, Monique M. Ryan, Sara E. Howden, Shireen R. Lamandé, Kathryn N. North
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102429- (2021)
To produce an in vitro model of nemaline myopathy, we reprogrammed the peripheral blood mononuclear cells (PBMCs) of a patient with a heterozygous p.Gly148Asp mutation in exon 3 of the ACTA1 gene to iPSCs. Using CRISPR/Cas9 gene editing we corrected
Externí odkaz:
https://doaj.org/article/fd458bd769a240bdab0c029e7e060663
Autor:
Natalie Charitakis, Agus Salim, Adam T. Piers, Kevin I. Watt, Enzo R. Porrello, David A. Elliott, Mirana Ramialison
Identifying spatially variable genes (SVGs) is a key step in the analysis of spatially resolved transcriptomics (SRT) data. SVGs provide biological insights by defining transcriptomic differences within tissues, which was previously unachievable usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86547c884e88b6f21d20a9b338f85826
https://doi.org/10.1101/2022.10.31.514623
https://doi.org/10.1101/2022.10.31.514623
Autor:
Neda R. Mehdiabadi, Choon Boon Sim, Belinda Phipson, Ravi K.R. Kalathur, Yuliangzi Sun, Celine J. Vivien, Menno ter Huurne, Adam T. Piers, James E. Hudson, Alicia Oshlack, Robert G. Weintraub, Igor E. Konstantinov, Nathan J. Palpant, David A. Elliott, Enzo R. Porrello
Publikováno v:
Circulation. 146(14)
Autor:
Holly M. Hayes, Julie Angerosa, Adam T. Piers, Jason D. White, Jane Koleff, Madeline Thurgood, Jessica Moody, Michael M. Cheung, Salvatore Pepe
Publikováno v:
Oxidative Medicine and Cellular Longevity.
Duchenne muscular dystrophy involves an absence of dystrophin, a cytoskeletal protein which supports cell structural integrity and scaffolding for signalling molecules in myocytes. Affected individuals experience progressive muscle degeneration that
Autor:
Annabelle Suter, Adam T. Piers, Chantal A. Coles, Peter J. Houweling, Penny McDonald, Shireen R. Lamandé, Alison Graham, Bridget Nielsen, Monique M. Ryan, Robin Forbes, Kathryn N. North, Sara E. Howden, Chrystal F. Tiong
Publikováno v:
Stem Cell Research, Vol 54, Iss, Pp 102429-(2021)
To produce an in vitro model of nemaline myopathy, we reprogrammed the peripheral blood mononuclear cells (PBMCs) of a patient with a heterozygous p.Gly148Asp mutation in exon 3 of the ACTA1 gene to iPSCs. Using CRISPR/Cas9 gene editing we corrected
Autor:
Christopher Kintakas, Adam T. Piers, Keryn G. Woodman, Tracie Webster, Chantal A. Coles, Su L Touslon, Gayle M. Smythe, Lavinia Gordon, Shireen R. Lamandé, Liam C. Hunt, Jason D. White
Publikováno v:
Human molecular genetics. 29(3)
Duchenne muscular dystrophy (DMD) is a lethal muscle wasting disorder caused by mutations in the DMD gene that lead to the absence or severe reduction of dystrophin protein in muscle. The mdx mouse, also dystrophin deficient, is the model most widely