Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Adam T. Austin"'
Autor:
Donald A. Bruun, Zhengyu Cao, Pamela J. Lein, Isaac N. Pessah, Susan Hulsizer, Stephen T. Vito, Adam T. Austin, Bora Inceoglu, Bruce D. Hammock, Daniel J. Tancredi, Michael A. Rogawski
Publikováno v:
Bruun, Donald A; Cao, Zhengyu; Inceoglu, Bora; Vito, Stephen T; Austin, Adam T; Hulsizer, Susan; et al.(2015). Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures.. Neuropharmacology, 95, 332-342. doi: 10.1016/j.neuropharm.2015.03.035. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/19v2x74d
Tetramethylenedisulfotetramine (TETS) is a potent convulsant GABAA receptor blocker. Mice receiving a lethal dose of TETS (0.15 mg/kg i.p.) are rescued from death by a high dose of diazepam (5 mg/kg i.p.) administered shortly after the second clonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7ddbe31ef2ea4030ca3d7857cc2b84
https://doi.org/10.1016/j.neuropharm.2015.03.035
https://doi.org/10.1016/j.neuropharm.2015.03.035
Autor:
Dorota Zolkowska, Pamela J. Lein, Stephen T. Vito, Adam T. Austin, Bora Inceoglu, Bruce D. Hammock, Michael A. Rogawski, Daniel J. Tancredi, Christopher N. Banks, Donald A. Bruun
Publikováno v:
Vito, Stephen T; Austin, Adam T; Banks, Christopher N; Inceoglu, Bora; Bruun, Donald A; Zolkowska, Dorota; et al.(2014). Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication.. Toxicology and applied pharmacology, 281(2), 185-194. doi: 10.1016/j.taap.2014.10.001. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/5v14199w
Toxicology and applied pharmacology, vol 281, iss 2
Toxicology and applied pharmacology, vol 281, iss 2
Tetramethylenedisulfotetramine (TETS) is a potent convulsant poison for which there is currently no approved antidote. The convulsant action of TETS is thought to be mediated by inhibition of type A gamma-aminobutyric acid receptor (GABAAR) function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab700315dd814415f7fb05610d6d642
https://doi.org/10.1016/j.taap.2014.10.001
https://doi.org/10.1016/j.taap.2014.10.001
Autor:
Douglas J. Rowland, Adam T. Austin, Daniel J. Tancredi, Simon R. Cherry, Jill L. Silverman, Yonggang Li, Donald A. Bruun, Brenna M. Flannery, David L. Kukis, Byron D. Ford, Pamela J. Lein, Christopher N. Banks
Publikováno v:
Flannery, BM; Bruun, DA; Rowland, DJ; Banks, CN; Austin, AT; Kukis, DL; et al.(2016). Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication. Journal of Neuroinflammation, 13(1), 267. doi: 10.1186/s12974-016-0744-y. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/73t348st
Journal of neuroinflammation, vol 13, iss 1
Journal of Neuroinflammation
Journal of neuroinflammation, vol 13, iss 1
Journal of Neuroinflammation
BackgroundAcute intoxication with organophosphorus (OP) cholinesterase inhibitors can trigger convulsions that progress to life-threatening status epilepticus. Survivors face long-term morbidity including mild-to-severe decline in memory. It is posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371e8eadfe5bc9b502825381952da2ba
http://www.escholarship.org/uc/item/73t348st
http://www.escholarship.org/uc/item/73t348st
