Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Adam T Nelson"'
Publikováno v:
Endocrinology
TLX (NR2E1), an orphan member of the nuclear receptor superfamily, is a transcription factor that has been described to be generally repressive in nature. It has been implicated in several aspects of physiology and disease. TLX is best known for its
Autor:
Erik R. Nelson, Jaena Park, Janet E. Sorrells, Ashabari Sprenger, Natalia Krawczynska, Svyatoslav Dvoretskiy, Stephen A. Boppart, Hyunjoon Kong, Marni D. Boppart, Adam T Nelson, Liqian Ma, Madeline A. Henn, Amy E. Baek, Sixian You, Anasuya Das Gupta, Brandi Patrice Smith, Yu-Heng Deng, Zeynep Madak-Erdogan, Hannah B. McDowell
Publikováno v:
Endocrinology
Cholesterol has been implicated in the clinical progression of breast cancer, a disease that continues to be the most commonly diagnosed cancer in women. Previous work has identified the cholesterol metabolite 27-hydroxycholesterol (27HC) as a major
Autor:
Madeline A. Henn, Liqian Ma, Sunghee Park, Amy E. Baek, Karan Menon, David J. Shapiro, Som G. Nanjappa, Sisi He, Sayyed Hamed Shahoei, Lawrence Wang, Adam T Nelson, Erik R. Nelson, Joy J. Chen, Chaeyeon Han, Anna Vardanyan
Publikováno v:
Cancer Lett
Breast cancer remains one of the leading causes of cancer mortality in the US. Elevated cholesterol is a major risk factor for breast cancer onset and recurrence, while cholesterol-lowering drugs, such as statins, are associated with a good prognosis
Autor:
Sayyed Hamed Shahoei, Madeline A. Henn, Erik R. Nelson, Varsha Vembar, Liqian Ma, Adam T Nelson, Ashley E Mathews, Yu Wang, Anna Vardanyan, Joy J. Chen, Lionel Apetoh
Publikováno v:
Journal of the Endocrine Society
Immune checkpoint blockade has had underwhelming responses in breast cancer, in part due to the highly immune suppressive microenvironment. As a result, breast cancer continues to be the second most common cancer-related mortality amongst women, prov
Autor:
Madeline A. Henn, Yu Wang, Tareq Saleh, Valerie J. Carpenter, Erik R. Nelson, Sisi He, Liqian Ma, Sayyed Hamed Shahoei, David A. Gewirtz, Michael J. Spinella, Adam T Nelson
Publikováno v:
Journal of the Endocrine Society. 5:A1019-A1019
Despite the development of various therapeutic strategies, breast cancer persists as the second leading cause of cancer-related death among women in the United States. While endocrine modulation and monoclonal antibody therapy have proved to be indis
Autor:
Liqian Ma, Anna Vardanyan, Sisi He, Varsha Vembar, Amy E. Baek, Adam T Nelson, Joy J. Chen, Erik R. Nelson, Joanna E. Burdette
Publikováno v:
Endocr Relat Cancer
There is an urgent need for more effective strategies to treat ovarian cancer. Elevated cholesterol levels are associated with a decreased progression-free survival time (PFS) while statins are protective. 27-Hydroxycholesterol (27HC), a primary meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0294b77d52cdfe2f1fab558ac7d00e43
https://europepmc.org/articles/PMC6824983/
https://europepmc.org/articles/PMC6824983/
Autor:
David J. Shapiro, Joy J. Chen, Sunghee Park, Som G. Nanjappa, Adam T Nelson, Amy E. Baek, Erik R. Nelson, Liqian Ma, Karan Menon, Sisi He, Madeline A. Henn, Lawrence Wang, Anna Vardanyan, Chaeyeon Han, Sayyed Hamed Shahoei
Publikováno v:
Cancer Immunology Research. 9:PR006-PR006
Breast cancer remains one of the leading causes of cancer mortality in the US. Elevated cholesterol is a major risk factor for breast cancer onset and recurrence, while cholesterol-lowering drugs, such as statins, are associated with a good prognosis
Autor:
Adam T Nelson, Varsha Vembar, Liqian Ma, Lionel Apetoh, Madeline A. Henn, Erik R. Nelson, Ashley E Mathews, Joy J. Chen, Sayyed Hamed Shahoei
Publikováno v:
Cancer Immunology Research. 8:A93-A93
Breast cancer continues to be the second most common cancer-related mortality among women, providing strong rationale for the development of new therapeutic approaches. Cholesterol and its metabolism have been implicated in the progression of breast
Autor:
Erik R. Nelson, Lionel Apetoh, Ashley E Mathews, Madeline A. Henn, Adam T Nelson, Varsha Vembar, Sayyed Hamed Shahoei, Liqian Ma, Joy J. Chen
Publikováno v:
Cancer Research. 80:P6-05
It has become clear that cholesterol metabolism and homeostasis play significant roles in the progression of breast cancer. Specifically, elevated circulating cholesterol is a poor prognostic, while patients taking cholesterol-lowering drugs such as