Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Adam T, Hoye"'
Autor:
Justin P. Wright, Jason R. Goodman, Yin-Guo Lin, Brian P. Lieberman, Jennifer Clemens, Luis F. Gomez, Qianwa Liang, Adam T. Hoye, Michael J. Pontecorvo, Kelly A. Conway
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:3797-3808
Purpose [18F]-labeled positron emission tomography (PET) radioligands permit in vivo assessment of Alzheimer’s disease biomarkers, including aggregated neurofibrillary tau (NFT) with [18F]flortaucipir. Due to structural similarities of flortaucipir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a270cb3b79eb97336e225570f85c6b2
https://doi.org/10.1007/s00259-022-05822-9
https://doi.org/10.1007/s00259-022-05822-9
Autor:
Adam T. Hoye, Hui Xiong
Publikováno v:
Synlett. 33:371-375
A synthesis of 2-aminopyridines from pyridine N-oxides via their corresponding N-(2-pyridyl)pyridinium salts has been demonstrated and investigated. The reaction sequence features a highly regioselective conversion of the N-oxide into its pyridinium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::570ab025fcc40b3853da64ab27e2496f
https://doi.org/10.1055/s-0040-1719865
https://doi.org/10.1055/s-0040-1719865
Autor:
Justin P, Wright, Jason R, Goodman, Yin-Guo, Lin, Brian P, Lieberman, Jennifer, Clemens, Luis F, Gomez, Qianwa, Liang, Adam T, Hoye, Michael J, Pontecorvo, Kelly A, Conway
Publikováno v:
European journal of nuclear medicine and molecular imaging. 49(11)
[[Under stringent wash conditions, specific [These data suggest neither MAO-A nor MAO-B binding will contribute significantly to the PET signal in cortical target areas relevant to the interpretation of [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2cc85af3a759bb339f4fbe36edae6c3
https://pubmed.ncbi.nlm.nih.gov/35596745
https://pubmed.ncbi.nlm.nih.gov/35596745
Autor:
Adam T. Hoye, Qi Liu, Karen TenDyke, Hongsheng Cheng, Amos B. Smith, Yongchun Shen, Chihui An
Publikováno v:
The Journal of Organic Chemistry
The design, synthesis, and biological evaluation of irciniastatin A (1) analogues, achieved by removal of three synthetically challenging structural units, as well as by functional group manipulation of the C(11) substituent of both irciniastatins A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d4fa6faae1e85b74fb4b547ed9dde4
http://europepmc.org/articles/PMC4782725
http://europepmc.org/articles/PMC4782725
Autor:
Jianxia Guo, Adam T. Hoye, Jan H. Beumer, Peter Wipf, Susan M. Christner, Julie L. Eiseman, Joel S. Greenberger, Melanie Ringeval, Robert A. Parise, Michael W. Epperly
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 150
JP4-039 radio-protects prior to, and radio-mitigates after ionizing radiation by neutralizing reactive oxygen species. We developed and validated an LC-MS/MS assay for the quantitation of JP4-039 in murine plasma. Methanol protein precipitation of 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4acec18e31bd55a45a57cb90ec5ae5
https://pubmed.ncbi.nlm.nih.gov/29245086
https://pubmed.ncbi.nlm.nih.gov/29245086
Autor:
Felipe Gomez, Kelly Conway, Lois Lazor, Brian P. Lieberman, Justin P. Wright, Jason Goodman, Qianwa Liang, Jennifer Clemens, Yin-Guo Lin, Adam T. Hoye
Publikováno v:
Alzheimer's & Dementia. 15:P131-P131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368706fd5ad0aa7601c5da7486b56a3c
https://doi.org/10.1016/j.jalz.2019.06.4280
https://doi.org/10.1016/j.jalz.2019.06.4280
Publikováno v:
Organic Letters. 14:4350-4353
The total synthesis and structural confirmation of the marine sponge cytotoxin (-)-irciniastatin B has been achieved via a unified strategy employing a late-stage, selective deprotection/oxidation sequence that provides access to both (+)-irciniastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd272fe3539778f2346362e295ae6ad
https://doi.org/10.1021/ol301783p
https://doi.org/10.1021/ol301783p
Publikováno v:
Journal of the American Chemical Society. 134:4533-4536
The unification of Anion Relay Chemistry (ARC) with the Takeda and Hiyama palladium-mediated cross-coupling processes to provide aryl-aryl, alkenyl-aryl, and alkenyl-alkenyl coupled products by exploiting a common silicon-based transfer agent has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811a26af733a9c09b3f288dcd79c7b3d
https://doi.org/10.1021/ja2120103
https://doi.org/10.1021/ja2120103
Autor:
Jianfei Jiang, Michael W. Epperly, Qing Zhao, Valerian E. Kagan, Adam T. Hoye, Peter Wipf, Natalia A. Belikova, Joel S. Greenberger
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 70:816-825
Purpose To evaluate the in vitro radioprotective effect of the mitochondria-targeted hemigramicidin S–conjugated 4-amino-2,2,6,6-tetramethyl-piperidine- N -oxyl (hemi-GS-TEMPO) 5-125 in γ-irradiated mouse embryonic cells and adenovirus-12 SV40 hyb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ae4ce8c4ba15bf779d62004fe1120a
https://doi.org/10.1016/j.ijrobp.2007.10.047
https://doi.org/10.1016/j.ijrobp.2007.10.047
Autor:
Adam T. Hoye, Martin G. Pomper, Xing Yang, Ying Chen, Sridhar Nimmagadda, Ronnie C. Mease, Mrudula Pullambhatla, Hassan M. Shallal, Ala Lisok, Yuchuan Wang, Giorgio Attardo, Hannah Edelman, Catherine A. Foss
Publikováno v:
Journal of medicinal chemistry. 59(1)
Radiolabeled urea-based low-molecular weight inhibitors of the prostate-specific membrane antigen (PSMA) are under intense investigation as imaging and therapeutic agents for prostate and other cancers. In an effort to provide agents with less nontar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7491001a1867593fd615eff9c1306d2
https://pubmed.ncbi.nlm.nih.gov/26629713
https://pubmed.ncbi.nlm.nih.gov/26629713