Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Adam Sychla"'
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Threshold-dependent gene drives (TDGDs) could be used to spread desirable traits through a population, and are likely to be less invasive and easier to control than threshold-independent gene drives. Engineered Genetic Incompatibi
Externí odkaz:
https://doaj.org/article/5ba0fd9c1007488282327b955c565269
Autor:
Ambuj Upadhyay, Nathan R Feltman, Adam Sychla, Anna Janzen, Siba R Das, Maciej Maselko, Michael Smanski
Publikováno v:
eLife, Vol 11 (2022)
Engineered Genetic Incompatibility (EGI) is a method to create species-like barriers to sexual reproduction. It has applications in pest control that mimic Sterile Insect Technique when only EGI males are released. This can be facilitated by introduc
Externí odkaz:
https://doaj.org/article/3a5fe20996cd467b9339ceeef3e60ec8
Rational search of genetic design space for a heterologous terpene metabolic pathway in Streptomyces
Publikováno v:
Metabolic Engineering. 77:1-11
Publikováno v:
Nucleic Acids Research.
CRISPR/Cas-based transcriptional activators have been developed to induce gene expression in eukaryotic and prokaryotic organisms. The main advantages of CRISPR/Cas-based systems is that they can achieve high levels of transcriptional activation and
Publikováno v:
Frontiers in Insect Science. 2
Engineered Genetic Incompatibility (EGI) is an engineered extreme underdominance genetic system wherein hybrid animals are not viable, functioning as a synthetic speciation event. There are several strategies in which EGI could be leveraged for genet
Autor:
Matthew H Zinselmeier, J. Armando Casas-Mollano, Adam Sychla, Stephen C Heinsch, Daniel F Voytas, Michael J Smanski
Understanding how the expression of genes impacts plant development and physiology is important for rationally engineering crop improvements. Programmable Transcription Activators (PTAs), including CRISPRa activators, have traditionally relied on a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aa7c2e3251a429fb57fd17f83d50c7b
https://doi.org/10.1101/2022.06.10.495638
https://doi.org/10.1101/2022.06.10.495638
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2464
Recent advances in DNA synthesis and assembly allow for genetic constructs to be designed and constructed in high throughput. Characterizing large numbers of variant genetic designs is not feasible with low-throughput and time-consuming plant transfo
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621639
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c4a886d2d9f7bedf49f0b11bbb217d
https://doi.org/10.1007/978-1-0716-2164-6_16
https://doi.org/10.1007/978-1-0716-2164-6_16
Autor:
Ambuj Upadhyay, Nathan R Feltman, Adam Sychla, Anna Janzen, Siba R Das, Maciej Maselko, Michael Smanski
Publikováno v:
eLife. 11
Engineered Genetic Incompatibility (EGI) is a method to create species-like barriers to sexual reproduction. It has applications in pest control that mimic Sterile Insect Technique when only EGI males are released. This can be facilitated by introduc