Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Adam Stonier"'
Publikováno v:
Biotechnology Journal
Increases in mammalian cell culture titres and densities have placed significant demands on primary recovery operation performance. This article presents a methodology which aims to screen rapidly and evaluate primary recovery technologies for their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e314726c7023d7697c70d12560211c
http://europepmc.org/articles/PMC4999028
http://europepmc.org/articles/PMC4999028
Autor:
Suzanne S. Farid, David Pain, Nina F. Thornhill, Nick Hutchinson, Adam Stonier, Ashley Westlake
Publikováno v:
Biotechnology Progress. 29:368-377
This article describes a decision-support tool to help pinpoint the potential root causes of sub-optimal short-term facility fit issues in biopharmaceutical facilities. This was achieved by creating a tool that integrated stochastic simulation with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ff2db8019ffe3d2eb40c101091be26
https://doi.org/10.1002/btpr.1678
https://doi.org/10.1002/btpr.1678
Publikováno v:
Biotechnology Journal
Mammalian cell culture material is often difficult to produce accurately and reproducibly for downstream studies. This article presents a methodology for the creation of a set of cell culture test materials where key variables including cell density,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::586ed3582f838bb54c86abc078a22d64
https://pubmed.ncbi.nlm.nih.gov/25377169
https://pubmed.ncbi.nlm.nih.gov/25377169
Autor:
Dave Pain, Ashley Westlake, Suzanne S. Farid, Nicholas Hutchinson, Adam Stonier, Nina F. Thornhill
Publikováno v:
ResearcherID
This paper describes a decision-support tool that integrates Monte Carlo simulation data derived using a stochastic discrete-event simulation model to mimic process fluctuations with advanced multivariate statistical techniques to help pinpoint the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9bb1bb766b09aee97ceb7dd4167ecb
https://doi.org/10.1016/b978-0-444-54298-4.50050-7
https://doi.org/10.1016/b978-0-444-54298-4.50050-7
Upstream advances in mammalian cell culture processes have increased pressures for downstream processes intensification efforts to alleviate downstream bottlenecks and improve process economics. This paper describes a decision support tool to facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b27ac2316057665bfb505fff833162d5
https://doi.org/10.1016/s1570-7946(09)70178-6
https://doi.org/10.1016/s1570-7946(09)70178-6
Publikováno v:
Biotechnology Journal; Jul2016, Vol. 11 Issue 7, p899-909, 11p
Publikováno v:
Biotechnology Journal; Jan2015, Vol. 10 Issue 1, p162-170, 9p
Integration of stochastic simulation with multivariate analysis: Short-term facility fit prediction.
Autor:
Stonier, Adam, Pain, David, Westlake, Ashley, Hutchinson, Nicholas, Thornhill, Nina F., Farid, Suzanne S.
Publikováno v:
Biotechnology Progress; Mar2013, Vol. 29 Issue 2, p368-377, 10p, 4 Black and White Photographs, 1 Chart, 4 Graphs
Publikováno v:
Biotechnology Progress; Jul2012, Vol. 28 Issue 4, p1019-1028, 10p, 4 Diagrams, 1 Chart, 5 Graphs
The European Symposium on Computer Aided Process Engineering (ESCAPE) series presents the latest innovations and achievements of leading professionals from the industrial and academic communities. The ESCAPE series serves as a forum for engineers, sc