Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Adam Stasiulewicz"'
Autor:
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 11, p e1010667 (2022)
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs that would aid vaccin
Externí odkaz:
https://doaj.org/article/a93dbfcd30ab48748e464f2830d40c68
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3957 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes the papain-like protease (PLpro). The protein not only plays an essential role in viral replication but also cleaves ubiquitin and ubiquitin-like interferon-stimulated gene 15 prote
Externí odkaz:
https://doaj.org/article/13d1cef9439e4b52942aaaabc875b462
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2778 (2020)
The endocannabinoid system (ECS) is one of the most crucial systems in the human organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of physiological processes, including nociception, mood regulation, cognitive func
Externí odkaz:
https://doaj.org/article/6afac12a14ec41bd8ecbbbcfe248f9cf
Autor:
Aleksandra Dąbrowska, Tomasz Pieńko, Przemysław Taciak, Katarzyna Wiktorska, Zdzisław Chilmonczyk, Aleksander P. Mazurek, Adam Stasiulewicz
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3231 (2018)
Here we present new derivatives of nucleoside reverse transcriptase inhibitors with a C20 fullerene. The computational chemistry methods used in this study evaluate affinity of designed compounds towards the HIV-1 reverse transcriptase (RT) binding s
Externí odkaz:
https://doaj.org/article/6206bd42b51b465d87061ad1d13d64d6
Autor:
Adam Stasiulewicz, Anna Lesniak, Magdalena Bujalska-Zadrożny, Tomasz Pawiński, Joanna I. Sulkowska
Publikováno v:
Journal of Chemical Information and Modeling. 63:1012-1027
Autor:
Adam Stasiulewicz, Anna Lesniak, Piotr Setny, Magdalena Bujalska-Zadrożny, Joanna I. Sulkowska
Publikováno v:
ACS Chemical Neuroscience. 13:2991-3007
Cannabinoid receptor type 1 (CB1) is an important modulator of many key physiological functions and thus a compelling molecular target. However, safe CB1 targeting is a non-trivial task. In recent years, there has been a surge of data indicating that
Autor:
Agata P. Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W. Maksymiuk, Marcin Drag, Joanna I. Sulkowska
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs that would aid vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f540ea164e5fe30d636283d3104c75f
https://www.repository.cam.ac.uk/handle/1810/344727
https://www.repository.cam.ac.uk/handle/1810/344727
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3957, p 3957 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences
Volume 22
Issue 8
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes the papain-like protease (PLpro). The protein not only plays an essential role in viral replication but also cleaves ubiquitin and ubiquitin-like interferon-stimulated gene 15 prote
Autor:
Adam Stasiulewicz, Ewa K. Nawrocka, Krzysztof Kazimierczuk, Piotr Setny, Agata P. Perlinska, Joanna I. Sulkowska
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 5, p e1007904 (2020)
PLoS Computational Biology, Vol 16, Iss 5, p e1007904 (2020)
S-adenosylmethionine (SAM) is one of the most important enzyme substrates. It is vital for the function of various proteins, including large group of methyltransferases (MTs). Intriguingly, some bacterial and eukaryotic MTs, while catalysing the same
Autor:
Aleksander P. Mazurek, Katarzyna Wiktorska, Przemyslaw Taciak, Adam Stasiulewicz, Tomasz Pieńko, Aleksandra Dąbrowska, Zdzisław Chilmonczyk
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3231 (2018)
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3231 (2018)
Here we present new derivatives of nucleoside reverse transcriptase inhibitors with a C20 fullerene. The computational chemistry methods used in this study evaluate affinity of designed compounds towards the HIV-1 reverse transcriptase (RT) binding s