Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Adam Sharp"'
Autor:
Justus Simon Israel, Laura-Maria Marcelin, Christian Thomas, Eva Szczyrbová, Susanne Fuessel, Martin Puhr, Johannes Linxweiler, Shivani Yalala, Wilbert T. Zwart, Aria Baniahmad, Jasper van Goubergen, Harri M. Itkonen, Adam Sharp, Edward O’Neill, Marc Pretze, Matthias Miederer, Holger H.H. Erb
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Continued exploration of the androgen receptor (AR) is crucial, as it plays pivotal roles in diverse diseases such as prostate cancer (PCa), serving as a significant therapeutic focus. Therefore, the Department of Urology Dresden hosted an i
Externí odkaz:
https://doaj.org/article/39e0ffdb610b4782878eda81fbb46bd2
Autor:
Mary Van Zyl, Anne Barell, Bridget Cooley, Janet Hanwell, Josie Parlak, Udai Banerji, Johann De Bono, Adam Sharp, Juanita Lopez, Nicolo Matteo Luca Battisti, Anna Minchom
Publikováno v:
Cancer Reports, Vol 7, Iss 6, Pp n/a-n/a (2024)
Abstract Background Though cancer is more prevalent in the older population, this patient group are underrepresented in phase I oncology trials. Aims We evaluated the use of a geriatric screening tool (SAOP3) in patients of 70 years of age or older w
Externí odkaz:
https://doaj.org/article/898ed05cc677458a94115355b7e29a02
Publikováno v:
Check List, Vol 19, Iss 6, Pp 833-838 (2023)
Clubiona hitchinsi Saaristo, 2002, previously known from the Seychelles and French Polynesia, is newly recorded from Ascension Island, based on comparison of the Ascension specimens against two paratypes. The first detailed figures of the endogyne, b
Externí odkaz:
https://doaj.org/article/cecb7ef51a984bb1bd70a5d4f6c65daa
Publikováno v:
African Invertebrates, Vol 64, Iss 3, Pp 291-302 (2023)
An updated checklist of the gnaphosid spiders of Ascension Island – comprising five species, in five genera – is presented, based on examination of historical and new specimens from across Ascension, including its islet Boatswain Bird Island. The
Externí odkaz:
https://doaj.org/article/e6bad5347b1549c28b4a71ae543c6eae
Autor:
Rafael Grochot, Suzanne Carreira, Susana Miranda, Ines Figueiredo, Claudia Bertan, Jan Rekowski, Wei Yuan, Ana Ferreira, Ruth Riisnaes, Antje Neeb, Bora Gurel, Maria de Los Dolores Fenor de la Maza, Christina Guo, Juliet Carmichael, Daniel Westaby, Joaquin Mateo, Adam Sharp, Terri P. McVeigh, Johann De Bono
Publikováno v:
European Urology Open Science, Vol 52, Iss , Pp 72-78 (2023)
Background: Germline mutations in the ataxia telangiectasia mutated (ATM) gene occur in 0.5–1% of the overall population and are associated with tumour predisposition. The clinical and pathological features of ATM-mutated prostate cancer (PC) are p
Externí odkaz:
https://doaj.org/article/eac68c6ede4f43d4a8673b793f11158f
Autor:
Beth Adamson, Nicholas Brittain, Laura Walker, Ruaridh Duncan, Sara Luzzi, Pasquale Rescigno, Graham Smith, Suzanne McGill, Richard J.S. Burchmore, Elaine Willmore, Ian Hickson, Craig N. Robson, Denisa Bogdan, Juan M. Jimenez-Vacas, Alec Paschalis, Jonathan Welti, Wei Yuan, Stuart R. McCracken, Rakesh Heer, Adam Sharp, Johann S. de Bono, Luke Gaughan
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Aberrant androgen receptor (AR) signaling drives prostate cancer (PC), and it is a key therapeutic target. Although initially effective, the generation of alternatively spliced AR variants (AR-Vs) compromises efficacy of treatments. In contrast to fu
Externí odkaz:
https://doaj.org/article/a880219dc98f4a75b656758c629cdcd9
Autor:
Ricardo Donners, Antonio Candito, Mihaela Rata, Adam Sharp, Christina Messiou, Dow-Mu Koh, Nina Tunariu, Matthew D. Blackledge
Publikováno v:
Cancers, Vol 16, Iss 9, p 1647 (2024)
(1) Background: We assessed the test–re-test repeatability of radiomics in metastatic castration-resistant prostate cancer (mCPRC) bone disease on whole-body diffusion-weighted (DWI) and T1-weighted Dixon MRI. (2) Methods: In 10 mCRPC patients, 1.5
Externí odkaz:
https://doaj.org/article/6886f301ce0840efb907237720cee35e
Publikováno v:
Cancer Treatment and Research Communications, Vol 28, Iss , Pp 100218- (2021)
Externí odkaz:
https://doaj.org/article/1c7210478d224aa39da90c415bc6c6fd
Autor:
Daniel Westaby, Juan M. Jimenez-Vacas, Ana Padilha, Andreas Varkaris, Steven P. Balk, Johann S. de Bono, Adam Sharp
Publikováno v:
Cancers, Vol 14, Iss 1, p 51 (2021)
Despite major improvements in the management of advanced prostate cancer over the last 20 years, the disease remains invariably fatal, and new effective therapies are required. The development of novel hormonal agents and taxane chemotherapy has impr
Externí odkaz:
https://doaj.org/article/aa3c811cfb7d42c4a21597aafa9003cd
Autor:
Rebeca Lozano, David Lorente, Isabel M. Aragon, Nuria Romero-Laorden, Paz Nombela, Joaquim Mateo, Alison H. M. Reid, Ylenia Cendón, Diletta Bianchini, Casilda Llacer, Shahneen K. Sandhu, Adam Sharp, Pasquale Rescigno, Teresa Garcés, Maria I. Pacheco, Penelope Flohr, Christophe Massard, Pedro P. López-Casas, Elena Castro, Johann S. de Bono, David Olmos
Publikováno v:
Cancers, Vol 13, Iss 10, p 2334 (2021)
Circulating tumor cell (CTC) enumeration and changes following treatment have been demonstrated to be superior to PSA response in determining mCRPC outcome in patients receiving AR signaling inhibitors but not taxanes. We carried out a pooled analysi
Externí odkaz:
https://doaj.org/article/25aa60de536743f59f084ad791f71abd