Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Adam Seger"'
Publikováno v:
The Journal of Applied Laboratory Medicine.
Background Lung cancer is the second leading cause of death in the United States. Lung cancer is often diagnosed in its late stage leading to a poor prognosis. Lung nodules are often described as indeterminate from CT scans resulting in lung biopsies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::557395cf90f4eb4bd47c904e057ade05
https://doi.org/10.1093/jalm/jfad021
https://doi.org/10.1093/jalm/jfad021
Autor:
Amanda L Fish, Rana Hasan, Michael Beggs, Bryce Cowgill, Angela Vallejo, Richard Torricelli, Veronica Wells, Rami Arfoosh, Jose Medina, Thomas DeMarini, Rabih El-Bizri, Denise Rebeor, Kimtuyen Nguyen, DeEtta DeBault, G. Allen, Kenneth Melby, David Miller, Adam Seger
Publikováno v:
Biomedical Research and Reviews. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::183aff0994efb91696186e27bff9e52b
https://doi.org/10.15761/brr.1000128
https://doi.org/10.15761/brr.1000128
Autor:
Akshar Lohith, Hyunsung John Kim, Michelle M. Maalouf, Paolo Actis, R. Adam Seger, Nader Pourmand, Boaz Vilozny
Publikováno v:
ACS nano, vol 8, iss 1
The ability to study the molecular biology of living single cells in heterogeneous cell populations is essential for next generation analysis of cellular circuitry and function. Here, we developed a single-cell nanobiopsy platform based on scanning i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23029687efca831405576048e0abe4a6
https://doi.org/10.1021/nn405097u
https://doi.org/10.1021/nn405097u
Autor:
Olufisayo Jejelowo, Boaz Vilozny, Jeff Nivala, Paolo Actis, R. Adam Seger, Nader Pourmand, Adam R. Rogers
Publikováno v:
Biosensors and Bioelectronics. 26:4503-4507
Signal Transduction by Ion NanoGating (STING) is a label-free technology based on functionalized quartz nanopipettes. The nanopipette pore can be decorated with a variety of recognition elements and the molecular interaction is transduced via a simpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015e50281522dfc1274fea9a1c67c8e2
https://doi.org/10.1016/j.bios.2011.05.010
https://doi.org/10.1016/j.bios.2011.05.010
Autor:
Nader Pourmand, Boaz Vilozny, R. Adam Seger, Marguerite Rinaudo, Paolo Actis, Xiang Li, Olufisayo Jejelowo
Publikováno v:
Langmuir. 27:6528-6533
Most of the research in the field of nanopore-based platforms is focused on monitoring ion currents and forces as individual molecules translocate through the nanopore. Molecular gating, however, can occur when target analytes interact with receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fe24389f361bab77190fc07e6eacbe
https://doi.org/10.1021/la2005612
https://doi.org/10.1021/la2005612
Autor:
Boaz Vilozny, Nader Pourmand, Catherine Penfold, Paolo Actis, R. Adam Seger, Michelle M. Maalouf
Manipulation and analysis of single cells is the next frontier in understanding processes that control the function and fate of cells. Herein we describe a single-cell injection platform based on nanopipettes. The system uses scanning microscopy tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27872d904e1b03957aeac243bdc0aa9f
https://europepmc.org/articles/PMC4406976/
https://europepmc.org/articles/PMC4406976/
The calcium ion response of a quartz nanopipette was enhanced by immobilization of calmodulin to the nanopore surface. Binding to the analyte is rapidly reversible in neutral buffer and requires no change in media or conditions to regenerate the rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319c77f1a2bfe7f9f0eac0924dfe0baa
https://europepmc.org/articles/PMC3155644/
https://europepmc.org/articles/PMC3155644/
Publikováno v:
Biophysical Journal. 100(3)
Solid-state nanopores are a promising platform for sensitive detection of many analytes, but modifying the surface of pores to impart selectivity is a challenge. We are applying the principle of signal transduction by ion nano-gating (STING) to use m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657be2e2154c50f3730f6bf6008f954f
Autor:
Mathias Bruendel, Michael Isaacson, Yasuhisa Ichihashi, Jeremy Hieb, Alexander Welle, R. Adam Seger, D.G. Rabus
Publikováno v:
SPIE Proceedings.
This paper describes the development of methods for the determination of the characteristics and the behavior of living neural cells. A technology which is used is the deep ultraviolet (DUV) modification of methylmethacrylate polymers which leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f39474f877e84666dfec5dd133af9b7
https://doi.org/10.1117/12.681015
https://doi.org/10.1117/12.681015
Publikováno v:
Biophysical Journal. 100:183a
Signal Transduction by Ion Nano-Gating (STING) technology is a label-free biosensor based on quartz nanopipettes capable of detecting DNA and proteins. Using conical quartz nanopipettes a Scanning Ion Conductance Microscope (SICM) was developed and u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d77015a97916b081e43adc96b6baaa6
https://doi.org/10.1016/j.bpj.2010.12.1219
https://doi.org/10.1016/j.bpj.2010.12.1219