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pro vyhledávání: '"Adam Saretzky"'
Autor:
Alfredo Garcia Venzor, Debra Toiber, Ekaterina Khrameeva, Anastasia Golova, Daniel Stein, Monica Einav, Shai Kaluski, Amir Mizrahi, Adam Saretzky, Zeev Slobodnik
Publikováno v:
Aging
Aging (Albany NY)
Aging (Albany NY)
Brain-specific SIRT6-KO mice present increased DNA damage, learning impairments, and neurodegenerative phenotypes, placing SIRT6 as a key protein in preventing neurodegeneration. In the aging brain, SIRT6 levels/activity decline, which is accentuated