Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Adam S Mangold"'
Autor:
Joanne F. Garbincius, Timothy S. Luongo, Pooja Jadiya, Alycia N. Hildebrand, Devin W. Kolmetzky, Adam S. Mangold, Rajika Roy, Jessica Ibetti, Mary Nwokedi, Walter J. Koch, John W. Elrod
Publikováno v:
Journal of Molecular and Cellular Cardiology. 167:52-66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76cd3af5f08208822279a228625b3d98
https://doi.org/10.1016/j.yjmcc.2022.03.001
https://doi.org/10.1016/j.yjmcc.2022.03.001
Autor:
Joanne F. Garbincius, Timothy S. Luongo, Jonathan P. Lambert, Adam S. Mangold, Emma K. Murray, Alycia N. Hildebrand, Pooja Jadiya, John W. Elrod
Publikováno v:
bioRxiv
BackgroundMitochondrial calcium (mCa2+) uptake through the mitochondrial calcium uniporter channel (mtCU) stimulates metabolism to meet acute increases in cardiac energy demand. However, excessivemCa2+uptake during stress, as in ischemia-reperfusion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5922de7c4c56848936d3308c62c1b185
https://doi.org/10.1101/2023.04.17.537222
https://doi.org/10.1101/2023.04.17.537222
Autor:
Joanne F Garbincius, Timothy Luongo, Jonathan P Lambert, Adam S Mangold, Devin Kolmetzky, Emma Murray, Alycia Hildebrand, Pooja Jadiya, Rajika Roy, Mary Nwokedi, Jessica Ibetti, Walter J Koch, John W Elrod
Publikováno v:
Circulation Research. 131
Acute mitochondrial calcium ( m Ca 2+ ) uptake stimulates bioenergetics to meet increased ATP demand, but when excessive predisposes to necrotic cell death. A major unresolved controversy is whether chronic alterations in cardiomyocyte m Ca 2+ homeos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0924ea9321950978fc4b524307b5e81
https://doi.org/10.1161/res.131.suppl_1.p3053
https://doi.org/10.1161/res.131.suppl_1.p3053
Autor:
Joanne F, Garbincius, Timothy S, Luongo, Pooja, Jadiya, Alycia N, Hildebrand, Devin W, Kolmetzky, Adam S, Mangold, Rajika, Roy, Jessica, Ibetti, Mary, Nwokedi, Walter J, Koch, John W, Elrod
Publikováno v:
J Mol Cell Cardiol
Mitochondrial calcium ((m)Ca(2+)) uptake couples changes in cardiomyocyte energetic demand to mitochondrial ATP production. However, excessive (m)Ca(2+) uptake triggers permeability transition and necrosis. Despite these established roles during acut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b602c733488aebf212c775fb6d5372f4
https://pubmed.ncbi.nlm.nih.gov/35358843
https://pubmed.ncbi.nlm.nih.gov/35358843
Autor:
Pooja Jadiya, Jonathan P. Lambert, Emma K Murray, Joanne F Garbincius, Adam S Mangold, Timothy S. Luongo, Alycia N Hildebrand, John W. Elrod
Publikováno v:
Circulation. 142
Calcium (Ca 2+ ) uptake into the mitochondrial matrix occurs via the mitochondrial Ca 2+ uniporter channel (mtCU) and tunes mitochondrial metabolism to meet acute changes in cellular ATP demand. However, the role of mtCU-dependent mitochondrial Ca 2+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5baa627628cb5e92ee464c4e1d3fdb
https://doi.org/10.1161/circ.142.suppl_3.16592
https://doi.org/10.1161/circ.142.suppl_3.16592
Autor:
Joanne F Garbincius, Alycia N Hildebrand, Jonathan P. Lambert, Timothy S. Luongo, Adam S Mangold, John W. Elrod, Emma K Murray, Pooja Jadiya
Publikováno v:
Circulation Research. 127
The mitochondrial calcium uniporter (MCU) forms the pore of the mitochondrial calcium uniporter channel (mtCU) and is required for rapid mitochondrial Ca 2+ ( m Ca 2+ ) uptake. MCU is necessary to increase cardiac energetics to fuel an increase in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c19bacc5d838fecab7071155084e1899
https://doi.org/10.1161/res.127.suppl_1.506
https://doi.org/10.1161/res.127.suppl_1.506