Zobrazeno 1 - 10
of 813
pro vyhledávání: '"Adam S Kibel"'
Autor:
Milena Braga-Basaria, Thomas G Travison, Mary-Ellen Taplin, Alexander Lin, Alyssa B Dufour, Daniel Habtemariam, Paul L Nguyen, Adam S Kibel, Praful Ravi, Richelle Bearup, Hannah Kackley, Hussein Kafel, Kieran Reid, Thomas Storer, Donald C Simonson, Marie McDonnell, Shehzad Basaria
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281508 (2023)
Androgen deprivation therapy (ADT), a cornerstone of treatment for patients with locally advanced and metastatic prostate cancer, is associated with many adverse effects, including osteoporosis, sexual dysfunction, fatigue, and vasomotor symptoms. It
Externí odkaz:
https://doaj.org/article/4cf46102272e4122abe95a4588531750
Autor:
Fei Chen, Burcu F Darst, Ravi K Madduri, Alex A Rodriguez, Xin Sheng, Christopher T Rentsch, Caroline Andrews, Wei Tang, Adam S Kibel, Anna Plym, Kelly Cho, Mohamed Jalloh, Serigne Magueye Gueye, Lamine Niang, Olufemi J Ogunbiyi, Olufemi Popoola, Akindele O Adebiyi, Oseremen I Aisuodionoe-Shadrach, Hafees O Ajibola, Mustapha A Jamda, Olabode P Oluwole, Maxwell Nwegbu, Ben Adusei, Sunny Mante, Afua Darkwa-Abrahams, James E Mensah, Andrew Anthony Adjei, Halimatou Diop, Joseph Lachance, Timothy R Rebbeck, Stefan Ambs, J Michael Gaziano, Amy C Justice, David V Conti, Christopher A Haiman
Publikováno v:
eLife, Vol 11 (2022)
Background: We recently developed a multi-ancestry polygenic risk score (PRS) that effectively stratifies prostate cancer risk across populations. In this study, we validated the performance of the PRS in the multi-ancestry Million Veteran Program an
Externí odkaz:
https://doaj.org/article/357704951c834856af7fc63a759e4c2d
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184166 (2017)
MicroRNAs (miRNAs) play important roles in cancer formation and progression by suppressing the production of key functional proteins at the post-transcriptional level in a sequence-specific manner. While differential expression of miRNAs is widely ob
Externí odkaz:
https://doaj.org/article/8b28177419a64fe5bb34e0f60ad50e19
Autor:
Edward J Saunders, Tokhir Dadaev, Daniel A Leongamornlert, Sarah Jugurnauth-Little, Malgorzata Tymrakiewicz, Fredrik Wiklund, Ali Amin Al Olama, Sara Benlloch, David E Neal, Freddie C Hamdy, Jenny L Donovan, Graham G Giles, Gianluca Severi, Henrik Gronberg, Markus Aly, Christopher A Haiman, Fredrick Schumacher, Brian E Henderson, Sara Lindstrom, Peter Kraft, David J Hunter, Susan Gapstur, Stephen Chanock, Sonja I Berndt, Demetrius Albanes, Gerald Andriole, Johanna Schleutker, Maren Weischer, Børge G Nordestgaard, Federico Canzian, Daniele Campa, Elio Riboli, Tim J Key, Ruth C Travis, Sue A Ingles, Esther M John, Richard B Hayes, Paul Pharoah, Kay-Tee Khaw, Janet L Stanford, Elaine A Ostrander, Lisa B Signorello, Stephen N Thibodeau, Daniel Schaid, Christiane Maier, Adam S Kibel, Cezary Cybulski, Lisa Cannon-Albright, Hermann Brenner, Jong Y Park, Radka Kaneva, Jyotsna Batra, Judith A Clements, Manuel R Teixeira, Jianfeng Xu, Christos Mikropoulos, Chee Goh, Koveela Govindasami, Michelle Guy, Rosemary A Wilkinson, Emma J Sawyer, Angela Morgan, COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative, UK Genetic Prostate Cancer Study Collaborators, UK ProtecT Study Collaborators, PRACTICAL Consortium, Douglas F Easton, Ken Muir, Rosalind A Eeles, Zsofia Kote-Jarai
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004129 (2014)
The HOXB13 gene has been implicated in prostate cancer (PrCa) susceptibility. We performed a high resolution fine-mapping analysis to comprehensively evaluate the association between common genetic variation across the HOXB genetic locus at 17q21 and
Externí odkaz:
https://doaj.org/article/ef4e48a676e14b05b1bb979807ceb684
Autor:
Logan G. Briggs, Grant L. Steele, Zhiyu Jason Qian, Sara Subbana, Khalid Y. Alkhatib, Muhieddine Labban, Bjoern J. Langbein, David-Dan Nguyen, Jacqueline Cellini, Kerry Kilbridge, Adam S. Kibel, Quoc-Dien Trinh, Huma Q. Rana, Alexander P. Cole
Publikováno v:
JCO Oncology Practice. 19:e784-e793
PURPOSE: Testing for pathogenic variants can aid in oncologic risk stratification and identification of targeted therapies. Despite known disparities in access to prostate cancer (PCa) care, little has been written about access to germline genetic te
Autor:
Lin Yang, Andrew Harper, Kellie R. Imm, Robert L. Grubb, Eric H. Kim, Graham A. Colditz, Kathleen Y. Wolin, Adam S. Kibel, Siobhan Sutcliffe
Publikováno v:
Urology. 175:137-143
Autor:
Kelvin A. Moses, Preston C. Sprenkle, Clinton Bahler, Geoffrey Box, Sigrid V. Carlsson, William J. Catalona, Douglas M. Dahl, Marc Dall’Era, John W. Davis, Bettina F. Drake, Jonathan I. Epstein, Ruth B. Etzioni, Thomas A. Farrington, Isla P. Garraway, David Jarrard, Eric Kauffman, Deborah Kaye, Adam S. Kibel, Chad A. LaGrange, Paul Maroni, Lee Ponsky, Brian Reys, Simpa S. Salami, Alejandro Sanchez, Tyler M. Seibert, Terrence M. Shaneyfelt, Marc C. Smaldone, Geoffrey Sonn, Mark D. Tyson, Neha Vapiwala, Robert Wake, Samuel Washington, Alice Yu, Bertram Yuh, Ryan A. Berardi, Deborah A. Freedman-Cass
Publikováno v:
Journal of the National Comprehensive Cancer Network. 21:236-246
The NCCN Guidelines for Prostate Cancer Early Detection provide recommendations for individuals with a prostate who opt to participate in an early detection program after receiving the appropriate counseling on the pros and cons. These NCCN Guideline
Autor:
Nicola Frego, Muhieddine Labban, Benjamin V. Stone, Mara Koelker, Khalid Alkhatib, Giovanni Lughezzani, Nicolò M. Buffi, Stuart R. Lipsitz, Joel S. Weissman, Sean A. Fletcher, Adam S. Kibel, Quoc‐Dien Trinh, Alexander P. Cole
Publikováno v:
The Prostate.
Autor:
Benjamin V. Stone, Muhieddine Labban, Dejan K. Filipas, Edoardo Beatrici, Stuart R. Lipsitz, Leonardo O. Reis, Adam S. Feldman, Adam S. Kibel, Alexander P. Cole, Alicia K. Morgans, Quoc-Dien Trinh
Publikováno v:
Clinical Genitourinary Cancer.
Autor:
Rodrigo J, Valderrábano, Karol, Pencina, Thomas W, Storer, Kieran F, Reid, Adam S, Kibel, Arthur L, Burnett, Grace, Huang, Tanya, Dorff, Fabiola, Privat, Catherine, Ghattas-Puylara, Lauren, Wilson, Nancy K, Latham, Mats, Holmberg, Shalender, Bhasin
Publikováno v:
Andrology. 11:93-102
Most men diagnosed with prostate cancer today have organ-confined disease and low risk of disease recurrence after radical prostatectomy. Testosterone deficiency in prostate cancer survivors contributes to impaired health-related quality of life but