Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adam S Husk"'
Autor:
Nobuyuki Matoba, Adam S Husk, Brian W Barnett, Michelle M Pickel, Charles J Arntzen, David C Montefiori, Atsushi Takahashi, Kazunobu Tanno, Satoshi Omura, Huyen Cao, Jason P Mooney, Carl V Hanson, Haruo Tanaka
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11143 (2010)
The development of a topical microbicide blocking the sexual transmission of HIV-1 is urgently needed to control the global HIV/AIDS pandemic. The actinomycete-derived lectin actinohivin (AH) is highly specific to a cluster of high-mannose-type glyca
Externí odkaz:
https://doaj.org/article/8da529b66fe640bba203fa649dd60c17
Autor:
Francois Villinger, Tiffany N. Grooms, Steven D. Hume, Carl V. Hanson, J. Calvin Kouokam, Krystal Teasley Hamorsky, Mary Kate Morris, Kenneth A. Rogers, Matthew Dent, Adam S. Husk, Nobuyuki Matoba
Publikováno v:
Molecular Therapy
High-mannose-type glycans (HMGs) are aberrantly enriched on HIV envelope glycoproteins. However, there is currently no drug selectively targeting HIV-associated HMGs. Here, we describe a novel HMG-targeting “lectibody,” a recombinant Fc-fusion pr
Autor:
Tiffany W. Grooms-Williams, Krystal Teasley Hamorsky, Nobuyuki Matoba, Lauren J. Bennett, Kenneth E. Palmer, Adam S. Husk
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:2076-2086
Broadly neutralizing monoclonal antibodies (bnMAbs) may offer powerful tools for HIV-1 preexposure prophylaxis, such as topical microbicides. However, this option is hampered due to expensive MAb biomanufacturing based on mammalian cell culture. To a
Autor:
Kazuhito Fujiyama, Adam S. Husk, Krystal Teasley Hamorsky, Lauren J. Moore, Bailey Nelson, Hiroyuki Kajiura, Jessica M. Jurkiewicz, J. Calvin Kouokam, Nobuyuki Matoba
Publikováno v:
Scientific Reports
Plant-based transient overexpression systems enable rapid and scalable production of subunit vaccines. Previously, we have shown that cholera toxin B subunit (CTB), an oral cholera vaccine antigen, is N-glycosylated upon expression in transgenic Nico
Publikováno v:
BIO-PROTOCOL. 4
Plant-based expression systems provide an alternative biomanufacturing platform for recombinant proteins (Matoba et al., 2011). In particular, plant virus-based vectors can overexpress proteins within days in the leaf tissue of Nicotiana benthamiana
Autor:
Shin-je Ghim, Joongho Joh, Hugh S. Mason, Maryam Zahin, Adam S. Husk, Sujita Khanal, Donald M. Miller, A. B. Jenson, Heribert Warzecha, Nobuyuki Matoba
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160995 (2016)
PLoS ONE, Vol 11, Iss 8, p e0160995 (2016)
Cervical cancer is the most common malignancy among women particularly in developing countries, with human papillomavirus (HPV) 16 causing 50% of invasive cervical cancers. A plant-based HPV vaccine is an alternative to the currently available virus-
Autor:
Michelle M. Pickel, Kazunobu Tanno, Nobuyuki Matoba, Charles J. Arntzen, David C. Montefiori, Satoshi Omura, Jason P. Mooney, Haruo Tanaka, Brian W. Barnett, Carl V. Hanson, Huyen Cao, Adam S. Husk, Atsushi Takahashi
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11143 (2010)
PLoS ONE
PLoS ONE
The development of a topical microbicide blocking the sexual transmission of HIV-1 is urgently needed to control the global HIV/AIDS pandemic. The actinomycete-derived lectin actinohivin (AH) is highly specific to a cluster of high-mannose-type glyca