Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Adam S Deardorff"'
Autor:
Robert EW Fyffe, Adam S Deardorff
Publikováno v:
Cell calcium. 107
Publikováno v:
The Journal of Physiology. 599:1391-1420
The spatial and temporal balance of spinal α-motoneuron (αMN) intrinsic membrane conductances underlie the neural output of the final common pathway for motor commands. Although the complete set and precise localization of αMN K+ channels and thei
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
C-boutons are important cholinergic modulatory loci for state-dependent alterations in motoneuron firing rate. Type 2 muscarinic acetylcholine (m2) receptors are concentrated postsynaptic to C-boutons, and m2 receptor activation increases motoneuron
Externí odkaz:
https://doaj.org/article/5117ab3cff74443d852b6f33f92b1d78
Publikováno v:
Journal of Educational Evaluation for Health Professions, Vol 11 (2014)
Purpose:Previous studies on team-based learning (TBL) in medical education demonstrated improved learner engagement, learner satisfaction, and academic performance; however, a paucity of information exists on modifications of the incentive structure
Externí odkaz:
https://doaj.org/article/1534ada479fc41c7b2d54423f6a45e5d
Muscle proprioceptors in adult rat: mechanosensory signaling and synapse distribution in spinal cord
Autor:
Hanna M. Gabriel, Robert E.W. Fyffe, Timothy C. Cope, Jacob A. Vincent, Adam S. Deardorff, Paul Nardelli, Thomas J. Burkholder
Publikováno v:
Journal of Neurophysiology. 118:2687-2701
The characteristic signaling and intraspinal projections of muscle proprioceptors best described in the cat are often generalized across mammalian species. However, species-dependent adaptations within this system seem necessary to accommodate asymme
Publikováno v:
The Journal of physiology. 597(14)
Key points Kv2 currents maintain and regulate motoneuron (MN) repetitive firing properties. Kv2.1 channel clustering properties are dynamic and respond to both high and low activity conditions. The enzyme calcineurin regulates Kv2.1 ion channel declu
Publikováno v:
Journal of Anatomy. 227:221-230
The health of primary sensory afferents supplying muscle has to be a first consideration in assessing deficits in proprioception and related motor functions. Here we discuss the role of a particular proprioceptor, the IA muscle spindle proprioceptor
Autor:
Shannon H. Romer, Robert C. Tracy, Adam S. Deardorff, Robert E.W. Fyffe, Marc W. Gelpi, Kathleen M. Dominguez
Publikováno v:
Brain Research. 1547:1-15
Pathophysiological responses to peripheral nerve injury include alterations in the activity, intrinsic membrane properties and excitability of spinal neurons. The intrinsic excitability of α-motoneurons is controlled in part by the expression, regul
Publikováno v:
Physiological Reports
Homeostatic plasticity occurs through diverse cellular and synaptic mechanisms, and extensive investigations over the preceding decade have established Kv2.1 ion channels as key homeostatic regulatory elements in several central neuronal systems. As