Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Adam S, Asch"'
Publikováno v:
Cells, Vol 13, Iss 17, p 1463 (2024)
Bladder cancer (BCa) is one of the most lethal genitourinary malignancies owing to its propensity for recurrence and poor survival. The biochemical pathway, signal transducer and activator of transcription 3 (STAT3), has gained significance as a mole
Externí odkaz:
https://doaj.org/article/fb84af2f6a7c4053877f9c9f1c961f7c
Autor:
Joshua M. Corbin, Constantin Georgescu, Lin Wang, Jonathan D. Wren, Magdalena Bieniasz, Chao Xu, Adam S. Asch, Maria J. Ruiz Echevarría
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 257-272 (2023)
Blocking androgen receptor signaling is the mainstay of therapy for advanced prostate cancer (PCa). However, acquired resistance to single agents targeting this pathway results in the development of lethal castration-resistant PCa. Combination therap
Externí odkaz:
https://doaj.org/article/41fabf28d4364d8697b56a2f8a9cd7e7
Autor:
Lisa Johnson, Yajia Zhang, Linda Su-Feher, Yeonju Lee, David A. Sallman, Adam S. Asch, Monzr M. Al Malki, Hyunjae Ryan Kim
Publikováno v:
HemaSphere, Vol 7, p e45153c5 (2023)
Externí odkaz:
https://doaj.org/article/5e14c20208aa474dbe439319678e09ee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Genomic instability (GI) in cancer facilitates cancer evolution and is an exploitable target for therapy purposes. However, specific genes involved in cancer GI remain elusive. Causal genes for GI via expressions have not been comprehensivel
Externí odkaz:
https://doaj.org/article/469da7247fcd443ba2cfc8a145e2b8a3
Autor:
Joshua M. Corbin, Constantin Georgescu, Jonathan D. Wren, Chao Xu, Adam S. Asch, Maria J. Ruiz-Echevarría
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 337-351 (2021)
Resistance to anti-androgen therapy in prostate cancer (PCa) is often driven by genetic and epigenetic aberrations in the androgen receptor (AR) and coregulators that maintain androgen signaling activity. We show that specific small RNAs downregulate
Externí odkaz:
https://doaj.org/article/7f27fc30f9d341459f7710042befb4d8
Autor:
Constantin Georgescu, Joshua M. Corbin, Sandra Thibivilliers, Zachary D. Webb, Yan D. Zhao, Jan Koster, Kar-Ming Fung, Adam S. Asch, Jonathan D. Wren, Maria J. Ruiz-Echevarría
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background The clinical behavior of prostate cancer (PCa) is variable, and while the majority of cases remain indolent, 10% of patients progress to deadly forms of the disease. Current clinical predictors used at the time of diagnosis have l
Externí odkaz:
https://doaj.org/article/7e9ac0c4083a40768ff6d2ebaf0c452b
Autor:
David A. Sallman, Monzr M. Al Malki, Adam S. Asch, Eunice S. Wang, Joseph G. Jurcic, Terrence J. Bradley, Ian W. Flinn, Daniel A. Pollyea, Suman Kambhampati, Tiffany N. Tanaka, Joshua F. Zeidner, Guillermo Garcia-Manero, Deepa Jeyakumar, Rami Komrokji, Jeffrey Lancet, Hagop M. Kantarjian, Lin Gu, Yajia Zhang, Anderson Tan, Mark Chao, Carol O'Hear, Giridharan Ramsingh, Indu Lal, Paresh Vyas, Naval G. Daver
Publikováno v:
Journal of Clinical Oncology. 41:2815-2826
PURPOSE Magrolimab is a monoclonal antibody that blocks cluster of differentiation 47, a don't-eat-me signal overexpressed on cancer cells. Cluster of differentiation 47 blockade by magrolimab promotes macrophage-mediated phagocytosis of tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e11b215e9336a1c069e5809c1a46c9
https://doi.org/10.1200/jco.22.01794
https://doi.org/10.1200/jco.22.01794
Publikováno v:
Future Science OA, Vol 6, Iss 7 (2020)
Background: Immune-related adverse events are associated with efficacy of immune checkpoint inhibitors (ICIs). We hypothesize that immune-mediated thrombocytopenia could be a biomarker for response to ICIs. Materials & methods: This retrospective stu
Externí odkaz:
https://doaj.org/article/4dd001446d8248e181b2ec45db483397
Autor:
Manish R. Patel, William Donnellan, Michael Byrne, Adam S. Asch, Amer M. Zeidan, Maria R. Baer, Amir T. Fathi, Andrew T. Kuykendall, Fred Zheng, Chris Walker, Lulu Cheng, Cindy Marando, Michael R. Savona
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7fcc232d5a395aa6a48ca719ecfdc3
https://doi.org/10.1016/j.clml.2023.05.002
https://doi.org/10.1016/j.clml.2023.05.002
Autor:
Chinthalapally V. Rao, Vernon E. Steele, Altaf Mohammed, Adam S. Asch, Stanley Lightfoot, Yuting Zhang, Gopal Pathuri, Gaurav Kumar, Venkateshwar Madka
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dcd3e8e24e6606896b888464e7bef4
https://doi.org/10.1158/1940-6207.22533802
https://doi.org/10.1158/1940-6207.22533802
