Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Adam R. Wolfe"'
Autor:
Adam R. Wolfe, Priyanka Chablani, Michael R. Siedow, Eric D. Miller, Steve Walston, Kari L. Kendra, Evan Wuthrick, Terence M. Williams
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background In patients with stage III melanoma, the use of adjuvant radiation therapy (RT) after lymph node dissection (LND) may be currently considered in selected high-risk patients to improve tumor control. Melanomas harbor BRAF mutations
Externí odkaz:
https://doaj.org/article/4aed581dd5ab4a64bc414077d7b5400f
Autor:
Adam R. Wolfe, Dhivya Prabhakar, Vedat O. Yildiz, Jordan M. Cloyd, Mary Dillhoff, Laith Abushahin, Dayssy Alexandra Diaz, Eric D. Miller, Wei Chen, Wendy L. Frankel, Anne Noonan, Terence M. Williams
Publikováno v:
Cancer Medicine, Vol 9, Iss 13, Pp 4711-4723 (2020)
Abstract We conducted an institutional study to compare the clinical and pathological efficacy between the neoadjuvant therapy (NAT)‐modified FOLFIRINOX (mFOLF) vs nanoparticle albumin–bound paclitaxel plus gemcitabine (nab‐P/G) for borderline
Externí odkaz:
https://doaj.org/article/3ba0bea06cf741efb65f72e32a2d27d5
Autor:
Terence M. Williams, Arnab Chakravarti, Kamalakannan Palanichamy, John R. Jacob, Zobeida Cruz-Monserrate, Jose G. Trevino, Duan-Liang Shyu, Linlin Yang, Laith Abushahin, Ahmad Hegazi, Ryan Robb, Adam R. Wolfe
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ca6a18e0fde3fdb8c3908d01973cad
https://doi.org/10.1158/1078-0432.22479275.v1
https://doi.org/10.1158/1078-0432.22479275.v1
Autor:
Terence M. Williams, Arnab Chakravarti, Kamalakannan Palanichamy, John R. Jacob, Zobeida Cruz-Monserrate, Jose G. Trevino, Duan-Liang Shyu, Linlin Yang, Laith Abushahin, Ahmad Hegazi, Ryan Robb, Adam R. Wolfe
Purpose:Concurrent gemcitabine and nab-paclitaxel treatment is one of the preferred chemotherapy regimens for metastatic and locally advanced pancreatic ductal adenocarcinoma (PDAC). Previous studies demonstrate that caveolin-1 (Cav-1) expression is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20da889f7fe060b5d5032af5bd61122a
https://doi.org/10.1158/1078-0432.c.6530174
https://doi.org/10.1158/1078-0432.c.6530174
Autor:
Terence M. Williams, Matthew D. Ringel, Sissy Jhiang, Motoyasu Saji, Marall Vedaie, Xiaoli Zhang, Amy Webb, Adam R. Wolfe, Changxian Shen, Linlin Yang, Ryan Robb
Purpose:Activating BRAF mutations, most commonly BRAFV600E, are a major oncogenic driver of many cancers. We explored whether BRAFV600E promotes radiation resistance and whether selectively targeting BRAFV600E with a BRAF inhibitor (vemurafenib, BRAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d449dc96068adde7f6712cd93b1c741b
https://doi.org/10.1158/1078-0432.c.6528108
https://doi.org/10.1158/1078-0432.c.6528108
Autor:
Terence M. Williams, Matthew D. Ringel, Sissy Jhiang, Motoyasu Saji, Marall Vedaie, Xiaoli Zhang, Amy Webb, Adam R. Wolfe, Changxian Shen, Linlin Yang, Ryan Robb
Supplementary Table 1. Thyroid cancer cells lines used in this study Supplementary Figure 1. AlamarBlue® proliferation assay of TPC-1 stable cell lines. Supplemental Figure 2. Assessment of MEK-ERK activation in TPC-1 BRAFV600E stable cells. Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4a92e48da6816efa805a780d2ef230
https://doi.org/10.1158/1078-0432.22472082.v1
https://doi.org/10.1158/1078-0432.22472082.v1
Publikováno v:
Cancer Drug Resistance. 5:926-38
Purpose/Objective(s): Discovery of genetic drivers of radioresistance is critical for developing novel therapeutic strategies to combine with radiotherapy of radioresistant PDAC. In this study, we used genome-wide RNA-seq to identify genes upregulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e458275942f7f4eeefc665fd5119442
https://doi.org/10.20517/cdr.2022.60
https://doi.org/10.20517/cdr.2022.60
Autor:
Mary Dillhoff, A.L.H. Arnett, Dominic DiCostanzo, Eric D. Miller, Adam R. Wolfe, Ansel Nalin, Allan Tsung, Michael Siedow, Jordan M. Cloyd, Dayssy Alexandra Diaz, Terence M. Williams, Aslam Ejaz
Publikováno v:
Radiotherapy and Oncology. 158:207-214
Neutrophil-to-lymphocyte ratio has been correlated with clinical outcomes in many cancers. We investigated whether the delta-NLR (ΔNLR) following radiation therapy (RT) could predict achieving surgical resection and the overall survival (OS) of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a52a16d44cbd19d0d89fa01899af4c8
https://doi.org/10.1016/j.radonc.2021.02.035
https://doi.org/10.1016/j.radonc.2021.02.035
Publikováno v:
Human Pathology. 109:1-11
Summary Pancreatic ductal adenocarcinoma (PDAC) is aggressive, with an overall five-year survival rate of 9%, and few patients are candidates for pancreatectomy at presentation. The role of neoadjuvant therapy (NAT) is evolving, especially for high-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80eb6c1bf0c1a79e2dfacc96478f6b2
https://doi.org/10.1016/j.humpath.2020.11.010
https://doi.org/10.1016/j.humpath.2020.11.010
Autor:
Adam R. Wolfe, Sarita Garg, Stetson Van Matre, Robin Eluvathingal, Oscar Zuniga, Henrique Rodrigues, Nükhet Aykin-Burns, Isabelle Racine Miousse
Publikováno v:
Cancer Research. 83:2839-2839
Purpose/Objective(s): Radiation therapy (RT) is the standard of care in patients with locally advanced rectal cancer, but not all patients respond equally to RT. KRAS-mutated (KRASmut) cancer cells are highly radioresistance and require higher levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f812a3fa08304cabaf93e2838a2d5a3b
https://doi.org/10.1158/1538-7445.am2023-2839
https://doi.org/10.1158/1538-7445.am2023-2839