Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Adam R Hall"'
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101632 (2014)
Among the different types of DNA damage that occur endogenously in the cell, depurination is especially prevalent. These lesions can initiate mutagenesis and have been implicated in a variety of diseases, including cancer. Here, we demonstrate a new
Externí odkaz:
https://doaj.org/article/61733b4ebd4948658ba79ab31412aa30
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9febef2b58a5425e8994fea2f9b2015f
Autor:
Diana C. Fasanello, Jin Su, Siyu Deng, Rose Yin, Marshall J. Colville, Joshua M. Berenson, Carolyn M. Kelly, Heather Freer, Alicia Rollins, Bettina Wagner, Felipe Rivas, Adam R. Hall, Elaheh Rahbar, Paul L. DeAngelis, Matthew J. Paszek, Heidi L. Reesink
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-17 (2021)
Abstract Background TNF-α-stimulated gene 6 (TSG-6) protein, a TNF-α-responsive hyaladherin, possesses enzymatic activity that can catalyze covalent crosslinks of the polysaccharide hyaluronic acid (HA) to another protein to form heavy chain-hyalur
Externí odkaz:
https://doaj.org/article/b0572c6f1b4e470196f16d9080910764
Autor:
Wenbin Wei, Jessica L. Faubel, Hemaa Selvakumar, Daniel T. Kovari, Joanna Tsao, Felipe Rivas, Amar T. Mohabir, Michelle Krecker, Elaheh Rahbar, Adam R. Hall, Michael A. Filler, Jennifer L. Washburn, Paul H. Weigel, Jennifer E. Curtis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Polymer brushes are often used to functionalise surfaces. Here, the authors report on the creation of high-density, regenerating hyaluronan brushes using hyaluronan synthase enzymes which can be patterned by photo-deactivation and demonstrate biocomp
Externí odkaz:
https://doaj.org/article/512ee6ef6392433884c3d7aba09c8777
Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
Autor:
Felipe Rivas, Osama K. Zahid, Heidi L. Reesink, Bridgette T. Peal, Alan J. Nixon, Paul L. DeAngelis, Aleksander Skardal, Elaheh Rahbar, Adam R. Hall
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by st
Externí odkaz:
https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd74
Autor:
Aleksander Skardal, Sean V. Murphy, Mahesh Devarasetty, Ivy Mead, Hyun-Wook Kang, Young-Joon Seol, Yu Shrike Zhang, Su-Ryon Shin, Liang Zhao, Julio Aleman, Adam R. Hall, Thomas D. Shupe, Andre Kleensang, Mehmet R. Dokmeci, Sang Jin Lee, John D. Jackson, James J. Yoo, Thomas Hartung, Ali Khademhosseini, Shay Soker, Colin E. Bishop, Anthony Atala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Many drugs have progressed through preclinical and clinical trials and have been available – for years in some cases – before being recalled by the FDA for unanticipated toxicity in humans. One reason for such poor translation from drug
Externí odkaz:
https://doaj.org/article/545c3d4e24814f1fb722fae0fa19632f
Autor:
Ian D. Wadsworth, Adam R. Hall
Publikováno v:
Nano Research. 15:9936-9942
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a30e02d219870154b780a824eb8700e
https://doi.org/10.1007/s12274-022-4631-9
https://doi.org/10.1007/s12274-022-4631-9
Autor:
Felipe Rivas, Dorothea Erxleben, Ian Smith, Elaheh Rahbar, Paul L. DeAngelis, Mary K. Cowman, Adam R. Hall
Publikováno v:
Am J Physiol Cell Physiol
The carbohydrate hyaluronan (or hyaluronic acid, HA) is found in all human tissues and biofluids where it has wide-ranging functions in health and disease that are dictated by both its abundance and size. Consequently, hyaluronan evaluation in physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd0f2339a9db49937b5df5139428f43
https://pubmed.ncbi.nlm.nih.gov/35196167
https://pubmed.ncbi.nlm.nih.gov/35196167
Publikováno v:
Scientific Reports, Vol 6, Iss 1, Pp 1-6 (2016)
Abstract 5-hydroxymethylcytosine (5 hmC), the oxidized form of 5-methylcytosine (5 mC), is a base modification with emerging importance in biology and disease. However, like most epigenetic elements, it is transparent to many conventional genetic tec
Externí odkaz:
https://doaj.org/article/ea941c6ded3640d690aca9ec52d7c1d4
Autor:
Iris E.M. de Jong, Mallory L. Hunt, Dongning Chen, Yu Du, Jessica Llewellyn, Kapish Gupta, Dorothea Erxleben, Felipe Rivas, Adam R. Hall, Emma E. Furth, Ali Naji, Chengyang Liu, Abhishek Dhand, Jason Burdick, Marcus G. Davey, Alan W. Flake, Robert J. Porte, Pierre A. Russo, J. William Gaynor, Rebecca G. Wells
IntroductionBiliary atresia (BA) is an obstructive cholangiopathy that initially affects the extrahepatic bile ducts (EHBDs) of neonates. The etiology is uncertain, but evidence points to a prenatal cause; however, the response of the fetal EHBD to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::272df5e6ba1a178955de99f3f74a99e8
https://doi.org/10.1101/2022.12.15.520656
https://doi.org/10.1101/2022.12.15.520656
