Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Adam R Abate"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171302 (2017)
Genetic interaction mapping is useful for understanding the molecular basis of cellular decision making, but elucidating interactions genome-wide is challenging due to the massive number of gene combinations that must be tested. Here, we demonstrate
Externí odkaz:
https://doaj.org/article/c1a2ca4f240a4bc9be8c0d0239794312
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0113549 (2015)
Microbial systems often exhibit staggering diversity, making the study of rare, interesting species challenging. For example, metagenomic analyses of mixed-cell populations are often dominated by the sequences of the most abundant organisms, while th
Externí odkaz:
https://doaj.org/article/c5e67752252a403aac16eb412c07114e
Autor:
Harish N. Vasudevan, Emily Payne, Cyrille L. Delley, S. John Liu, Kanish Mirchia, Matthew J. Sale, Sydney Lastella, Maria Sacconi Nunez, Calixto-Hope G. Lucas, Charlotte D. Eaton, Tim Casey-Clyde, Stephen T. Magill, William C. Chen, Steve E. Braunstein, Arie Perry, Line Jacques, Alyssa T. Reddy, Melike Pekmezci, Adam R. Abate, Frank McCormick, David R. Raleigh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Schwann cell tumors are the most common cancers of the peripheral nervous system and can arise in patients with neurofibromatosis type-1 (NF-1) or neurofibromatosis type-2 (NF-2). Functional interactions between NF1 and NF2 and broader mecha
Externí odkaz:
https://doaj.org/article/a34dc09304394fd3ae1c29c108fd0bbd
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62961 (2013)
The ability to add reagents to drops in a sequential fashion is necessary for numerous applications of microfluidics in biology. An important method for accomplishing this is picoinjection, a technique in which reagents are injected into aqueous drop
Externí odkaz:
https://doaj.org/article/e70716a8e499409a9807ab48470e65c5
Autor:
Iain C. Clark, Michael A. Wheeler, Hong-Gyun Lee, Zhaorong Li, Liliana M. Sanmarco, Shravan Thaploo, Carolina M. Polonio, Seung Won Shin, Giulia Scalisi, Amy R. Henry, Joseph M. Rone, Federico Giovannoni, Marc Charabati, Camilo Faust Akl, Dulce M. Aleman, Stephanie E. J. Zandee, Alexandre Prat, Daniel C. Douek, Eli A. Boritz, Francisco J. Quintana, Adam R. Abate
Publikováno v:
Nature, vol 614, iss 7947
Nature
Nature
Multiple sclerosis is a chronic inflammatory disease of the central nervous system1. Astrocytes are heterogeneous glial cells that are resident in the central nervous system and participate in the pathogenesis of multiple sclerosis and its model expe
Publikováno v:
Lab on a Chip. 23:2371-2377
We describe a microfluidic approach to print double emulsions on demand in air, allowing each double emulsion droplet to be printed with the desired inner cores.
Autor:
Thomas Moragues, Diana Arguijo, Thomas Beneyton, Cyrus Modavi, Karolis Simutis, Adam R. Abate, Jean-Christophe Baret, Andrew J. deMello, Douglas Densmore, Andrew D. Griffiths
Publikováno v:
Nature Reviews Methods Primers. 3
Autor:
Michael A. Wheeler, Iain C. Clark, Hong-Gyun Lee, Zhaorong Li, Mathias Linnerbauer, Joseph M. Rone, Manon Blain, Camilo Faust Akl, Gavin Piester, Federico Giovannoni, Marc Charabati, Joon-Hyuk Lee, Yoon-Chul Kye, Joshua Choi, Liliana M. Sanmarco, Lena Srun, Elizabeth N. Chung, Lucas E. Flausino, Brian M. Andersen, Veit Rothhammer, Hiroshi Yano, Tomer Illouz, Stephanie E. J. Zandee, Carolin Daniel, David Artis, Marco Prinz, Adam R. Abate, Vijay K. Kuchroo, Jack P. Antel, Alexandre Prat, Francisco J. Quintana
Publikováno v:
Science
Cell–cell interactions in the central nervous system play important roles in neurologic diseases. However, little is known about the specific molecular pathways involved, and methods for their systematic identification are limited. Here, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716c964e8fd9ff8c09dd7ebbf702e31d
https://europepmc.org/articles/PMC10066924/
https://europepmc.org/articles/PMC10066924/
Publikováno v:
Analytical chemistry, vol 94, iss 21
Current methods for fabricating microparticles offer limited control over size and shape. Here, we demonstrate a droplet microfluidic method to form polyhedral microparticles with controlled concavity. By manipulating Laplace pressure, buoyancy, and
Autor:
Geoffrey K. Zath, Ralph A. Sperling, Carter W. Hoffman, Dimitri A. Bikos, Reha Abbasi, Adam R. Abate, David A. Weitz, Connie B. Chang
Publikováno v:
Lab on a Chip. 22:4735-4745
In drop-based microfluidics, an aqueous sample is partitioned into drops using individual pump sources that drive water and oil into a drop-making device. Parallelization of drop-making devices is necessary to achieve high-throughput screening of mul