Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Adam Pickard"'
Autor:
Katherine Kellett, Adam Pickard, Kate Fisher, Adam Mitchell, Ross Dunne, Craig Smith, Karl Kadler, Nigel Hooper
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100116- (2024)
Externí odkaz:
https://doaj.org/article/634cd77155dc4be4a81d587b929aca57
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 8, Iss 1 (2023)
Objectives The trauma tertiary survey (TTS) is an essential part of the continued care for major trauma patients which is performed to ensure that all injuries have been identified and none have been overlooked during the patient’s stay. Although t
Externí odkaz:
https://doaj.org/article/be5aba891deb4fc7bc9dd7e3ebc9aeae
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009840 (2021)
COVID-19 vaccines based on the Spike protein of SARS-CoV-2 have been developed that appear to be largely successful in stopping infection. However, therapeutics that can help manage the disease are still required until immunity has been achieved glob
Externí odkaz:
https://doaj.org/article/33c38e8b624545e7a21beda01b97b102
Publikováno v:
Cells, Vol 9, Iss 9, p 2070 (2020)
The ability to quantitate a protein of interest temporally and spatially at subcellular resolution in living cells would generate new opportunities for research and drug discovery, but remains a major technical challenge. Here, we describe dynamic, h
Externí odkaz:
https://doaj.org/article/22ee6241cb5f44dfabdc2f7f1d31dfff
Autor:
Adam Pickard, Simon S McDade, Marie McFarland, W Glenn McCluggage, Cosette M Wheeler, Dennis J McCance
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004988 (2015)
Cervical cancer is a multi-stage disease caused by human papillomaviruses (HPV) infection of cervical epithelial cells, but the mechanisms regulating disease progression are not clearly defined. Using 3-dimensional organotypic cultures, we demonstrat
Externí odkaz:
https://doaj.org/article/dc2b8358171145e0a3242e21d20dfb5a
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8369 (2010)
p300 functions as a transcriptional co-activator to regulate many cellular responses such as cell growth, transformation, development and differentiation. It has been shown to affect the transcriptional activity of p53 which regulates p21(Waf1/CIP1)
Externí odkaz:
https://doaj.org/article/3bd5f51f04a54468b90d13d5b3f0de0d
Autor:
Dennis J. McCance, Simon S. McDade, Jacqueline A. James, Shauna M. Lambe, Gerard P. Quinn, Stephanie G. Craig, Adam Pickard, Kirtiman Srivastava
Figure S5 shows (A) venn diagram comparing E6/E7-HFK TP63 ChIP-seq peaks with published normal HFK TP63 ChIP-seq (McDade et al, 2014) (B) Visualisation of E6/E7 and normal HFK TP63 ChIP-seq tracks around CDH1 loci annotated with Encode histone modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff3826c7032c6d824af0d87b2aa10c9
https://doi.org/10.1158/1078-0432.22476041
https://doi.org/10.1158/1078-0432.22476041
Autor:
Dennis J. McCance, Simon S. McDade, Jacqueline A. James, Shauna M. Lambe, Gerard P. Quinn, Stephanie G. Craig, Adam Pickard, Kirtiman Srivastava
Purpose: To investigate the regulation of epithelial-to-mesenchymal transition (EMT) in head and neck squamous cell carcinoma (HNSCC) and its importance in tumor invasion.Experimental Design: We use a three-dimensional invasive organotypic raft cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cfa047a3682e6646c245b0b39b90e7
https://doi.org/10.1158/1078-0432.c.6529274
https://doi.org/10.1158/1078-0432.c.6529274
Autor:
Adam Pickard, Francesca Amoroso, Kelsey McCulloch, Andrew Erickson, Ashwin Sachdeva, Rebecca Steele, Debayan Mukherjee, Margaret Dellett, Jonathan McComb, Laura McCaffery, Claire A. Hart, Michael D. Brown, Simon McDade, David Waugh, Noel Clarke, Karl Butterworth, Tim Illidge, Tuomas Mirtti, Ian M. Overton, Ian G. Mills
Understanding the impact of radiotherapy on the evolution of treatment resistant prostate cancer is critical for selecting effective treatment combinations. Whilst activation of Type 1 interferon signalling is a hallmark of how cells respond to viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c32725fe5788159a4e2f72ed57adcae2
https://doi.org/10.1101/2022.09.23.509205
https://doi.org/10.1101/2022.09.23.509205
Autor:
Patrick Dancer, Adam Pickard, Wiktoria Potocka, Kayleigh Earle, Rachael Fortune-Grant, Karl Kadler, Margherita Bertuzzi, Sara Gago
Awareness that fungal coinfection complicates viral respiratory infections causing worse disease outcome has recently emerged. The environmental fungus Aspergillus fumigatus (Af) has been reported as the main driver of fungal coinfection in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d808948c87f6db2607434ff86a576d05
https://doi.org/10.1101/2022.04.13.488236
https://doi.org/10.1101/2022.04.13.488236