Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adam Pavlíček"'
Publikováno v:
Diagnostics, Vol 14, Iss 9, p 917 (2024)
The focus of this study, and the subject of this article, resides in the conceptually funded usability evaluation of an application of descriptive models to a specific dataset obtained from the East Slovak Institute of Heart and Vascular Diseases tar
Externí odkaz:
https://doaj.org/article/6cbc3b891bbf4f17ba6c1620349245b2
Autor:
Edmund C. Lee, Tania Valencia, Charles Allerson, Annelie Schairer, Andrea Flaten, Matanel Yheskel, Kara Kersjes, Jian Li, Sole Gatto, Mandeep Takhar, Steven Lockton, Adam Pavlicek, Michael Kim, Tiffany Chu, Randy Soriano, Scott Davis, John R. Androsavich, Salma Sarwary, Tate Owen, Julia Kaplan, Kai Liu, Graham Jang, Steven Neben, Philip Bentley, Timothy Wright, Vishal Patel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Autosomal dominant polycystic kidney disease (ADPKD) is a leading genetic cause of end-stage renal disease with limited treatment options. Here the authors discover and characterize a microRNA inhibitor as a potential treatment for ADPKD.
Externí odkaz:
https://doaj.org/article/bbe08759988a47b08a2411574e862c56
Autor:
Gallen Triana-Baltzer, Adam Pavlicek, Ariadne Goulart, Hanhua Huang, Steven Pirie-Shepherd, Nancy Levin
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80132 (2013)
The clinical efficacy of anti-angiogenic therapies has been difficult to predict, and biomarkers that can predict responsiveness are sorely needed in this era of personalized medicine. CVX-060 is an angiopoietin-2 (Ang2) targeting therapeutic, consis
Externí odkaz:
https://doaj.org/article/3655843bcd774251830c885c172e740a
Autor:
Nathan V. Lee, Maruja E. Lira, Adam Pavlicek, Jingjing Ye, Dana Buckman, Shubha Bagrodia, Sreesha P. Srinivasa, Yongjun Zhao, Samuel Aparicio, Paul A. Rejto, James G. Christensen, Keith A. Ching
Publikováno v:
PLoS ONE, Vol 7, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/5e076b51a84e4e379bd3dc42c835b79d
Autor:
Nathan V Lee, Maruja E Lira, Adam Pavlicek, Jingjing Ye, Dana Buckman, Shubha Bagrodia, Sreesha P Srinivasa, Yongjun Zhao, Samuel Aparicio, Paul A Rejto, James G Christensen, Keith A Ching
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39653 (2012)
Targeting cancers with amplified or abnormally activated c-Met (hepatocyte growth factor receptor) may have therapeutic benefit based on nonclinical and emerging clinical findings. However, the eventual emergence of drug resistant tumors motivates th
Externí odkaz:
https://doaj.org/article/5a094d31cc15407e9cb13f26db934534
Autor:
Natalay Kouprina, Vladimir N Noskov, Adam Pavlicek, N Keith Collins, Pamela D Schoppee Bortz, Chris Ottolenghi, Dmitri Loukinov, Paul Goldsmith, John I Risinger, Jung-Hyun Kim, V Anne Westbrook, Gregory Solomon, Hanna Sounders, John C Herr, Jerzy Jurka, Victor Lobanenkov, David Schlessinger, Vladimir Larionov
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e359 (2007)
The sperm protein associated with nucleus in the X chromosome (SPANX) genes cluster at Xq27 in two subfamilies, SPANX-A/D and SPANX-N. SPANX-A/D is specific for hominoids and is fairly well characterized. The SPANX-N gave rise to SPANX-A/D in the hom
Externí odkaz:
https://doaj.org/article/eb55759c6a8b47629bffb4a26a4f7f80
Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion.
Autor:
Natalay Kouprina, Adam Pavlicek, Ganeshwaran H Mochida, Gregory Solomon, William Gersch, Young-Ho Yoon, Randall Collura, Maryellen Ruvolo, J Carl Barrett, C Geoffrey Woods, Christopher A Walsh, Jerzy Jurka, Vladimir Larionov
Publikováno v:
PLoS Biology, Vol 2, Iss 5, p E126 (2004)
Primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by global reduction in cerebral cortical volume. The microcephalic brain has a volume comparable to that of early hominids, raising the possibility that some MCPH genes may ha
Externí odkaz:
https://doaj.org/article/7f886bad3f7d4c3c9efd3d992ff00af3