Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Adam Packard"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51737 (2012)
The embryonic olfactory epithelium (OE) generates only a very few olfactory sensory neurons when the basic helix-loop-helix transcription factor, ASCL1 (previously known as MASH1) is eliminated by gene mutation. We have closely examined the structure
Externí odkaz:
https://doaj.org/article/7978988152224aa4af32144e616b8e23
Publikováno v:
Development
Ret signaling promotes branching morphogenesis during kidney development, but the underlying cellular mechanisms remain unclear. While Ret-expressing progenitor cells proliferate at the ureteric bud tips, some of these cells exit the tips to generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f53fb8471fe8f7b9666d6e6ad45f28
https://pubmed.ncbi.nlm.nih.gov/33914865
https://pubmed.ncbi.nlm.nih.gov/33914865
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
The family of olfactory receptors (ORs) subserves the sense of smell and includes both functional alleles and pseudogenes, the latter identified by mutations resulting in frame shift or premature truncation. During neuronal differentiation, nonfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d76d36433500e25fe3dceb0d2cda82d
https://pubmed.ncbi.nlm.nih.gov/32020011
https://pubmed.ncbi.nlm.nih.gov/32020011
Autor:
Hui Zong, Anna-Katerina Hadjantonakis, Anna Ferrer-Vaquer, Cristina Cebrian, Frank Costantini, Adler Ju, Odyssé Michos, Melissa H. Little, Kylie Georgas, Paul Riccio, Alexander N. Combes, Adam Packard
Publikováno v:
Developmental Cell. 27:319-330
SummaryThe ureteric bud is an epithelial tube that undergoes branching morphogenesis to form the renal collecting system. Although development of a normal kidney depends on proper ureteric bud morphogenesis, the cellular events underlying this proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba670a35de5139d18acc11c441b6f5f0
https://doi.org/10.1016/j.devcel.2013.09.001
https://doi.org/10.1016/j.devcel.2013.09.001
Progenitor cell capacity of NeuroD1-expressing globose basal cells in the mouse olfactory epithelium
Publikováno v:
The Journal of Comparative Neurology. 519:3580-3596
The basic helix-loop-helix transcription factor NeuroD1 is expressed in embryonic and adult mouse olfactory epithelium (OE), as well as during epithelial regeneration, suggesting that it plays an important role in olfactory neurogenesis. We character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529c3cf07022704d0670b6b193331efb
https://doi.org/10.1002/cne.22726
https://doi.org/10.1002/cne.22726
Autor:
James E. Schwob, Zhen Guo, Richard C. Krolewski, Glen L. Manglapus, Margaret T. Harris, Adam Packard
Publikováno v:
The Journal of Comparative Neurology. 518:4395-4418
The olfactory epithelium maintains stem and progenitor cells that support the neuroepithelium’s life-long capacity to reconstitute after injury. However, the identity of the stem cells – and their regulation – remain poorly defined. The transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e546cf170e08d677a56bd9b5b99d578
https://doi.org/10.1002/cne.22463
https://doi.org/10.1002/cne.22463
Autor:
Jesse Peterson, Brian M. Lin, Julie H. Coleman, Daniel B. Herrick, Woochan Jang, James E. Schwob, Nikolai Schnittke, Adam Packard
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(36)
Adult tissue stem cells can serve two broad functions: to participate actively in the maintenance and regeneration of a tissue or to wait in reserve and participate only when activated from a dormant state. The adult olfactory epithelium, a site for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adc5fd2498984ba9784a517f536aeab
https://pubmed.ncbi.nlm.nih.gov/26305958
https://pubmed.ncbi.nlm.nih.gov/26305958
Ongoing, lifelong neurogenesis maintains the neuronal population of the olfactory epithelium in the face of piecemeal neuronal turnover and restores it following wholesale loss. The molecular phenotypes corresponding to different stages along the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019e9e4772c88c6152fe1deaf6233124
https://europepmc.org/articles/PMC3887395/
https://europepmc.org/articles/PMC3887395/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e51737 (2012)
PLoS ONE, Vol 7, Iss 12, p e51737 (2012)
The embryonic olfactory epithelium (OE) generates only a very few olfactory sensory neurons when the basic helix-loop-helix transcription factor, ASCL1 (previously known as MASH1) is eliminated by gene mutation. We have closely examined the structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4b17022959c257f27fc2ceac11149a
http://europepmc.org/articles/PMC3524087
http://europepmc.org/articles/PMC3524087
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0155167 (2016)
PLoS ONE, Vol 11, Iss 5, p e0155167 (2016)
In the adult olfactory epithelium, the transcription factors Pax6 and Sox2 are co-expressed in sustentacular cells, horizontal basal cells (HBCs), and less-differentiated globose basal cells (GBCs)-both multipotent and transit amplifying categories-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36fecb5693724ee13a8ae05aea78458
https://doi.org/10.1371/journal.pone.0155167
https://doi.org/10.1371/journal.pone.0155167