Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adam P. Treder"'
Autor:
Annie Doucet, Conor C. G. Scully, Eric Marsault, Jennifer L. Hickey, John Mancuso, Andrei K. Yudin, Marie-Claude Tremblay, Serge Zaretsky, Adam P. Treder
Publikováno v:
Chemistry - A European Journal. 21:9249-9255
The first solid-phase parallel synthesis of macrocyclic peptides using three-component coupling driven by aziridine aldehyde dimers is described. The method supports the synthesis of 9- to 18-membered aziridine-containing macrocycles, which are then
Publikováno v:
Organic letters. 16(17)
The first application of aziridine aldehyde dimers in solid-phase synthesis is reported. The solid-supported disrupted Ugi condensation between an aziridine aldehyde dimer, isonitrile, and backbone-anchored amino acids delivered N-acyl aziridine inte
Publikováno v:
Synthesis. :2281-2283
An efficient synthesis of selectively protected (25)-1,2,4-triaminobutane from L-glutamic acid via (25)-N 4 -benzyloxy-carbonyl-2,4-diaminobutanamid is described.
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(3)
Compilation of agmatine structure and imidazoline ring leads to a new family of imidazoline/alpha(2)-adrenoceptor ligands, 4(5)-(2-aminoethyl)imidazoline derivatives. Constraining of the guanidine moiety into heterocyclic ring improved the affinities