Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Adam P. Sage"'
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 19, Iss 1, Pp 1-8 (2023)
Abstract Background Allergic disease is on the rise. Waitlists for specialists are long, and many referred patients have already received prior allergic assessment, either by a certified Allergist, Primary Care Provider, or other Specialist. It is im
Externí odkaz:
https://doaj.org/article/83e99d2114ff48538d9199c433e70d49
Autor:
Victor D. Martinez, Adam P. Sage, Brenda C. Minatel, Erin A. Marshall, E. Magda Price, Daiana D. Becker-Santos, Wendy P. Robinson, Wan L. Lam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The placenta is vital to embryonic development and requires a finely-tuned pattern of gene expression, achieved in part by its unique epigenetic landscape. Piwi-interacting RNAs (piRNAs) are a class of small-non-coding RNA with established r
Externí odkaz:
https://doaj.org/article/4806d1b9d0fd42b4979aeb71fa7166a4
Autor:
Brenda C. Minatel, David E. Cohn, Michelle E. Pewarchuk, Mateus C. Barros-Filho, Adam P. Sage, Greg L. Stewart, Erin A. Marshall, Nikita Telkar, Victor D. Martinez, Patricia P. Reis, Wendy P. Robinson, Wan L. Lam
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Dysregulation of ubiquitin-proteasome pathway genes through copy number alteration, promoter hypomethylation, and miRNA deregulation is involved in cancer development and progression. Further characterizing alterations in these genes may uncover nove
Externí odkaz:
https://doaj.org/article/ace3059240c94cd381da45536a11944b
Autor:
Greg L. Stewart, Adam P. Sage, Katey S. S. Enfield, Erin A. Marshall, David E. Cohn, Wan L. Lam
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
BackgroundLong non-coding RNAs (lncRNAs) have long been implicated in cancer-associated phenotypes. Recently, a class of lncRNAs, known as cis-acting, have been shown to regulate the expression of neighboring protein-coding genes and may represent un
Externí odkaz:
https://doaj.org/article/cdfe1ae65c9e4eb7be5843068ea2abff
Autor:
Brenda C. Minatel, Adam P. Sage, Christine Anderson, Roland Hubaux, Erin A. Marshall, Wan L. Lam, Victor D. Martinez
Publikováno v:
Environment International, Vol 112, Iss , Pp 183-197 (2018)
More than 200 million people in 70 countries are exposed to arsenic through drinking water. Chronic exposure to this metalloid has been associated with the onset of many diseases, including cancer. Epidemiological evidence supports its carcinogenic p
Externí odkaz:
https://doaj.org/article/424ec43f603f47c0ab2be91c385fa2c3
Autor:
Brenda C. Minatel, Victor D. Martinez, Kevin W. Ng, Adam P. Sage, Tomas Tokar, Erin A. Marshall, Christine Anderson, Katey S. S. Enfield, Greg L. Stewart, Patricia P. Reis, Igor Jurisica, Wan L. Lam
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-6 (2018)
Abstract MicroRNAs (miRNAs) are crucial regulators of gene expression in normal development and cellular homeostasis. While miRNA repositories contain thousands of unique sequences, they primarily contain molecules that are conserved across several t
Externí odkaz:
https://doaj.org/article/17bf2ab7578d49079a071c1e19f013b2
Autor:
Leigha D. Rock, Brenda C. Minatel, Erin A. Marshall, Florian Guisier, Adam P. Sage, Mateus Camargo Barros-Filho, Greg L. Stewart, Cathie Garnis, Wan L. Lam
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Head and neck squamous cell carcinoma (HNSCC) has a poor survival rate mainly due to late stage diagnosis and recurrence. Despite genomic efforts to identify driver mutations and changes in protein-coding gene expression, developing effective diagnos
Externí odkaz:
https://doaj.org/article/fa5fdcfaec9e46ec814413c38c2d175d
Autor:
Greg L. Stewart, Katey S. S. Enfield, Adam P. Sage, Victor D. Martinez, Brenda C. Minatel, Michelle E. Pewarchuk, Erin A. Marshall, Wan L. Lam
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Transcriptome sequencing has led to the widespread identification of long non-coding RNAs (lncRNAs). Subsequently, these genes have been shown to hold functional importance in human cellular biology, which can be exploited by tumors to drive the hall
Externí odkaz:
https://doaj.org/article/d75c45ccac5a40dbaea668333e7c2cbd
Autor:
Adam P. Sage, Brenda C. Minatel, Erin A. Marshall, Victor D. Martinez, Greg L. Stewart, Katey S. S. Enfield, Wan L. Lam
Publikováno v:
International Journal of Genomics, Vol 2018 (2018)
Despite advancements in therapeutic strategies, diagnostic and prognostic molecular markers of kidney cancer remain scarce, particularly in patients who do not harbour well-defined driver mutations. Recent evidence suggests that a large proportion of
Externí odkaz:
https://doaj.org/article/f54a107c85904e1e86d81ac0b2fbf2cc
Autor:
Adam P. Sage, Hyun Kyung Lee, Joshua Dalmann, Susan Lin, Simran Samra, Areesha Salman, Kate L. Del Bel, Wenhui Laura Li, Anna Lehman, Stuart E. Turvey, Cornelius F. Boerkoel, Phillip A. Richmond
Publikováno v:
American Journal of Medical Genetics Part A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4d7bf727ad71c65afb95d8361967214
https://doi.org/10.1002/ajmg.a.63249
https://doi.org/10.1002/ajmg.a.63249