Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Adam P. Buzby"'
Autor:
S. Munir Alam, Guido Ferrari, Thomas N. Denny, Stephen D. Schmidt, Mark K. Louder, Brandy M. Ward, Norman L. Letvin, Hugh C. Welles, Rosemarie D. Mason, Ling Shen, Celia C. LaBranche, Raphael Gottardo, Kathryn E. Foulds, Kelly E. Seaton, Martha Nason, Robert T. Bailer, Robert A. Seder, Will Fischer, Linh Mach, Mario Roederer, John R. Mascola, Georgia D. Tomaras, Bette T. Korber, Srinivas S. Rao, John Paul Todd, Brandon F. Keele, Adam P. Buzby, Gary J. Nabel, Richard A. Koup, Zhi-Yong Yang, David C. Montefiori, Wenjuan Gu
Publikováno v:
Nature
A major challenge for the development of a highly effective AIDS vaccine is the identification of mechanisms of protective immunity. To address this question, we used a nonhuman primate challenge model with simian immunodeficiency virus (SIV). We sho
Autor:
Eric J. Arts, Srinivas S. Rao, Brennan S. Dirk, Colin Venner, Yong Gao, Mohammed Asmal, Linh Mach, Gabrielle Nickel, Meijuan Tian, Corinne Luedemann, Adam P. Buzby, Jimmy D. Dikeakos, Harikrishnan Balachandran, Norman L. Letvin, Sophie Lane
Publikováno v:
Virology. 499
For studies on vaccines and therapies for HIV disease, SIV-HIV chimeric viruses harboring the HIV-1 env gene (SHIVenv) remain the best virus in non-human primate models. However, there are still very few SHIVenv viruses that can cause AIDS in non-CD8
Autor:
John R. Mascola, James B. Whitney, Corinne Luedemann, Jinrong Zhang, Peter T. Hraber, Srinivas S. Rao, Laura M. Brassard, Gary J. Nabel, Alan Dodson, John Paul Todd, Wendy W. Yeh, Adam P. Buzby, So-Yon Lim, Bette T. Korber, Norman L. Letvin, Ling Shen
Publikováno v:
Journal of Virology. 85:10389-10398
There is considerable variability in host susceptibility to human immunodeficiency virus type 1 (HIV-1) infection, but the host genetic determinants of that variability are not well understood. In addition to serving as a block for cross-species retr
Publikováno v:
Virology. 406:48-55
The recently reported modest success of the RV144 Thai trial vaccine regimen in preventing HIV-1 acquisition has focused interest on the potential contribution to that protection of vaccine-elicited CD4(+) T cell responses. We evaluated the induction
Autor:
Keith G. Mansfield, Barton F. Haynes, Norman L. Letvin, Robert Parks, Adam P. Buzby, Harikrishnan Balachandran, David S Quinn, Hua-Xin Liao, Chun-Yen Tsao, Barbara K. Felber, Ruijin Zhang, James Theiler, Mark Muldoon, Angela Carville, Sydeaka Watson, George N. Pavlakis, Sampa Santra, James J. Szinger, Will Fischer, Bette T. Korber
Publikováno v:
Nature Medicine. 16:324-328
Vaccine design is challenging when the infectious agent is genetically diverse. Polyvalent 'mosaic' antigens might be used to address this challenge, and these two studies show promising results in monkeys infected with HIV-1.
Autor:
Angela Carville, Kevin R. Carlson, Birgit Korioth-Schmitz, Norman L. Letvin, Harikrishnan Balachandran, Barton F. Haynes, Mark Cayabyab, Yue Sun, Adam P. Buzby, William R. Jacobs, Ayako Miura
Publikováno v:
Journal of Virology. 83:5505-5513
While mycobacteria have been proposed as vaccine vectors because of their persistence and safety, little has been done systematically to optimize their immunogenicity in nonhuman primates. We successfully generated recombinant Mycobacterium bovis BCG
Autor:
Charles R. Brown, Adam P. Buzby, Russell Byrum, Simoy Goldstein, Jörn E. Schmitz, Vanessa M. Hirsch, Roland Zahn, Gordon J. Freeman, Melisa D. Rett, Norman L. Letvin, Yue Sun, Birgit Korioth-Schmitz
Publikováno v:
Journal of Virology. 82:11577-11588
African green monkeys (AGM) do not develop overt signs of disease following simian immunodeficiency virus (SIV) infection. While it is still unknown how natural hosts like AGM can cope with this lentivirus infection, a large number of investigations
Publikováno v:
Journal of Virology. 81:8009-8015
It has long been appreciated that CD4 + T lymphocytes are dysfunctional in human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV)-infected individuals, and it has recently been shown that HIV/SIV infections are associated with a drama
Autor:
L. Jean Patterson, Vaniambadi S. Kalyanaraman, Thorsten Demberg, Megan J. Heath, Kay Larsen, Norman L. Letvin, Birgit Korioth-Schmitz, Irene Kalisz, Adam P. Buzby, Eun Mi Lee, David Venzon, Barbara Ensoli, Richard Grant, Ruth H. Florese, Aurelio Cafaro, Dilani Dombagoda, Ranajit Pal, David C. Montefiori, Marjorie Robert-Guroff
Publikováno v:
Journal of Virology. 81:3414-3427
We previously demonstrated that replication-competent adenovirus (Ad)-simian immunodeficiency virus (SIV) recombinant prime/protein boost regimens elicit potent immunogenicity and strong, durable protection of rhesus macaques against SIVmac251. Addit
Autor:
Cathal Seoighe, Jinrong Zhang, Harikrishnan Balachandran, Peter B. Gilbert, Wendy W. Yeh, So-Yon Lim, Srinivas S. Rao, Miguel Lacerda, James B. Whitney, John Paul Todd, Ling Shen, Stephen D. Schmidt, Alan Dodson, Mohammed Asmal, John R. Mascola, Philip J. Norris, Michael S. Seaman, Linh Mach, Adam P. Buzby, Rebecca Gelman, Sheila M. Keating, David C. Montefiori, George M. Shaw, Gary J. Nabel, Norman L. Letvin, Michael G. Hudgens, Yue Sun
The RV144 vaccine trial in Thailand demonstrated that an HIV vaccine could prevent infection in humans and highlights the importance of understanding protective immunity against HIV. We used a nonhuman primate model to define immune and genetic mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830de3c57cb19f6a1d1fb68b53c84500