Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Adam P Geballe"'
Autor:
Annabel T Olson, Yuqi Kang, Anushka M Ladha, Songli Zhu, Chuan Bian Lim, Behnam Nabet, Michael Lagunoff, Taranjit S Gujral, Adam P Geballe
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011169 (2023)
Kaposi's sarcoma-associated herpesvirus (KSHV) causes several human diseases including Kaposi's sarcoma (KS), a leading cause of cancer in Africa and in patients with AIDS. KS tumor cells harbor KSHV predominantly in a latent form, while typically
Externí odkaz:
https://doaj.org/article/7bdbcc8d08244e078bda190c159e2904
Publikováno v:
PLoS Genetics, Vol 18, Iss 10, p e1010460 (2022)
Upstream open reading frames (uORFs) are present in over half of all human mRNAs. uORFs can potently regulate the translation of downstream open reading frames through several mechanisms: siphoning away scanning ribosomes, regulating re-initiation, a
Externí odkaz:
https://doaj.org/article/9812c9c1286b4802a16601e35f8fc26b
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009088 (2021)
Cytomegaloviruses (CMVs) are generally unable to cross species barriers, in part because prolonged coevolution with one host species limits their ability to evade restriction factors in other species. However, the limitation in host range is incomple
Externí odkaz:
https://doaj.org/article/10dab8affdc84303a71b630eaae0e918
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005966 (2016)
During millions of years of coevolution with their hosts, cytomegaloviruses (CMVs) have succeeded in adapting to overcome host-specific immune defenses, including the protein kinase R (PKR) pathway. Consequently, these adaptations may also contribute
Externí odkaz:
https://doaj.org/article/ab0b54bb9b5d43be8e92e07d8a95796b
Publikováno v:
eLife, Vol 5 (2016)
IFIT (interferon-induced with tetratricopeptide repeats) proteins are critical mediators of mammalian innate antiviral immunity. Mouse IFIT1 selectively inhibits viruses that lack 2'O-methylation of their mRNA 5' caps. Surprisingly, human IFIT1 does
Externí odkaz:
https://doaj.org/article/522fe0b3efad45cc8df911d1fb0c2004
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1004002 (2014)
The majority of recently emerging infectious diseases in humans is due to cross-species pathogen transmissions from animals. To establish a productive infection in new host species, viruses must overcome barriers to replication mediated by diverse an
Externí odkaz:
https://doaj.org/article/5b62cfb866064f33b0bd91a2b29ab9fd
Publikováno v:
bioRxiv
Myxovirus resistance proteins (MxA and MxB) are interferon-induced proteins that exert antiviral activity against a diverse range of RNA and DNA viruses. In primates, MxA has been shown to inhibit myxoviruses, bunyaviruses, and hepatitis B virus, whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7046aea4bc523be31e7d9f269de542
https://europepmc.org/articles/PMC10312577/
https://europepmc.org/articles/PMC10312577/
Autor:
Annabel T. Olson, Yuqi Kang, Anushka M. Ladha, Chuan Bian Lim, Michael Lagunoff, Taran S. Gujral, Adam P. Geballe
Publikováno v:
bioRxiv
Kaposi’s sarcoma-associated herpesvirus (KSHV) causes several human diseases including Kaposi’s sarcoma (KS), a leading cause of cancer in Africa and in patients with AIDS. KS tumor cells harbor KSHV predominantly in a latent form, while typicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093c46e59ab65d9f8ebe53e849b505d2
https://europepmc.org/articles/PMC9915688/
https://europepmc.org/articles/PMC9915688/