Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Adam Miles"'
Autor:
Yasmina Noubia Abdiche, Andy Yik Yeung, Irene Ni, Donna Stone, Adam Miles, Winse Morishige, Andrea Rossi, Pavel Strop
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169535 (2017)
Here we describe how real-time label-free biosensors can be used to identify antibodies that compete for closely adjacent or minimally overlapping epitopes on their specific antigen via a mechanism of antibody displacement. By kinetically perturbing
Externí odkaz:
https://doaj.org/article/4675a84d453f48769f8c0e99ac1659fc
Autor:
Yasmina Noubia Abdiche, Adam Miles, Josh Eckman, Davide Foletti, Thomas J Van Blarcom, Yik Andy Yeung, Jaume Pons, Arvind Rajpal
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92451 (2014)
Here, we demonstrate how array-based label-free biosensors can be applied to the multiplexed interaction analysis of large panels of analyte/ligand pairs, such as the epitope binning of monoclonal antibodies (mAbs). In this application, the larger th
Externí odkaz:
https://doaj.org/article/e1995642182a41caada3267f6a733df6
Autor:
Ken Hodge, Adam Miles
Publikováno v:
Applied Sport, Exercise, and Performance Psychology ISBN: 9780429503702
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89b17677e6b26a743da1935d01ec1ff
https://doi.org/10.4324/9780429503702-10
https://doi.org/10.4324/9780429503702-10
Autor:
Joshua Adam Miles, Jarom Glen Sederholm, Dean R. Wheeler, John E. Vogel, Edmund McKay Shumway, Brian A. Mazzeo
Publikováno v:
ECS Meeting Abstracts. :487-487
Publikováno v:
The Sport Psychologist. 30:101-112
The purpose of this study was to explore the stress, emotion, and coping (SEC) experiences of elite cricketers leading up to and on the day of their first competitive fixture of the season. Four elite male cricketers (M = 21.25, SD = 1.5) completed S
Autor:
Yik Andy Yeung, Boustany Leila Marie, Yasmina Noubia Abdiche, Winse Morishige, Shelley Izquierdo, Harriman William Don, Adam Miles, Rian Harriman, Xiaodi Deng, Lei Zhu
Publikováno v:
mAbs
The ability of monoclonal antibodies (mAbs) to target specific antigens with high precision has led to an increasing demand to generate them for therapeutic use in many disease areas. Historically, the discovery of therapeutic mAbs has relied upon th
Publikováno v:
mAbs
Non-human primate (NHP) studies are often an essential component of antibody development efforts before human trials. Because the efficacy or toxicity of candidate antibodies may depend on their interactions with Fcγ receptors (FcγR) and their resu
Autor:
Donna Marie Stone, Andy Yik Yeung, Yasmina Noubia Abdiche, Adam Miles, Pavel Strop, Winse Morishige, Andrea Rossi, Irene Ni
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169535 (2017)
PLoS ONE
PLoS ONE
Here we describe how real-time label-free biosensors can be used to identify antibodies that compete for closely adjacent or minimally overlapping epitopes on their specific antigen via a mechanism of antibody displacement. By kinetically perturbing
High-throughput epitope binning of therapeutic monoclonal antibodies: why you need to bin the fridge
Publikováno v:
Drug Discovery Today. 19:1040-1044
Analytical tools are evolving to meet the need for the higher-throughput characterization of therapeutic monoclonal antibodies. An antibody's epitope is arguably its most important property because it underpins its functional activity but, because ep