Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adam Mabbutt"'
Autor:
Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Jessica Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew White, Sally Sharpe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy. To this end, 34 rhesus macaques were vaccinated with BCG
Externí odkaz:
https://doaj.org/article/2c2a236866d34cea8189ad6904100b82
Autor:
Alexandra L. Morrison, Charlotte Sarfas, Laura Sibley, Jessica Williams, Adam Mabbutt, Mike J. Dennis, Steve Lawrence, Andrew D. White, Mark Bodman-Smith, Sally A. Sharpe
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1604 (2023)
Intravenously (IV) delivered BCG provides superior tuberculosis (TB) protection compared with the intradermal (ID) route in non-human primates (NHPs). We examined how γδ T cell responses changed in vivo after IV BCG vaccination of NHPs, and whether
Externí odkaz:
https://doaj.org/article/8cdbb2b4d36443c98f5fbd9003c1ea1c
Autor:
Francisco J. Salguero, Andrew D. White, Gillian S. Slack, Susan A. Fotheringham, Kevin R. Bewley, Karen E. Gooch, Stephanie Longet, Holly E. Humphries, Robert J. Watson, Laura Hunter, Kathryn A. Ryan, Yper Hall, Laura Sibley, Charlotte Sarfas, Lauren Allen, Marilyn Aram, Emily Brunt, Phillip Brown, Karen R. Buttigieg, Breeze E. Cavell, Rebecca Cobb, Naomi S. Coombes, Alistair Darby, Owen Daykin-Pont, Michael J. Elmore, Isabel Garcia-Dorival, Konstantinos Gkolfinos, Kerry J. Godwin, Jade Gouriet, Rachel Halkerston, Debbie J. Harris, Thomas Hender, Catherine M. K. Ho, Chelsea L. Kennard, Daniel Knott, Stephanie Leung, Vanessa Lucas, Adam Mabbutt, Alexandra L. Morrison, Charlotte Nelson, Didier Ngabo, Jemma Paterson, Elizabeth J. Penn, Steve Pullan, Irene Taylor, Tom Tipton, Stephen Thomas, Julia A. Tree, Carrie Turner, Edith Vamos, Nadina Wand, Nathan R. Wiblin, Sue Charlton, Xiaofeng Dong, Bassam Hallis, Geoffrey Pearson, Emma L. Rayner, Andrew G. Nicholson, Simon G. Funnell, Julian A. Hiscox, Mike J. Dennis, Fergus V. Gleeson, Sally Sharpe, Miles W. Carroll
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Non-human primates are important animal models for studying SARS-CoV-2 infection. Here, Salguero et al. directly compare rhesus and cynomolgus macaques and show that both species represent COVID-19 disease of mild clinical cases, and provide a lung h
Externí odkaz:
https://doaj.org/article/87631802f4e34ba091e1f0a793783536
Autor:
Andrew D. White, Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Kevin Bewley, Colin Churchward, Susan Fotheringham, Konstantinos Gkolfinos, Karen Gooch, Alastair Handley, Holly E. Humphries, Laura Hunter, Chelsea Kennard, Stephanie Longet, Adam Mabbutt, Miriam Moffatt, Emma Rayner, Tom Tipton, Robert Watson, Yper Hall, Mark Bodman-Smith, Fergus Gleeson, Mike Dennis, Francisco J. Salguero, Miles Carroll, Helen McShane, William Cookson, Julian Hopkin, Sally Sharpe
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The tuberculosis vaccine, Bacille Calmette-Guerin (BCG), also affords protection against non-tuberculous diseases attributable to heterologous immune mechanisms such as trained innate immunity, activation of non-conventional T-cells, and cross-reacti
Externí odkaz:
https://doaj.org/article/ccaf950828974926a6824fc4d8c72894
Autor:
Laura Sibley, Charlotte Sarfas, Alexandra L Morrison, Jessica J Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew D White, Sally Sharpe
The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy. To this end, 34 rhesus macaques were vaccinated with BCG within se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8cf723a40aea8523354c2b471cb88c2
https://doi.org/10.21203/rs.3.rs-2890669/v1
https://doi.org/10.21203/rs.3.rs-2890669/v1
Autor:
Nadina Wand, Irene Taylor, Didier Ngabo, Vanessa Lucas, Rebecca Cobb, Rachel Halkerston, Susan A. Fotheringham, Stephanie Leung, Alexandra L. Morrison, Tom Tipton, Holly E. Humphries, Bassam Hallis, Phillip Brown, Kerry J Godwin, Stephen Thomas, Isabel García-Dorival, Emily Brunt, Robert J. Watson, Thomas Hender, Charlotte Nelson, Laura Hunter, Andrew White, Gillian S. Slack, Michael J. Elmore, Owen Daykin-Pont, Nathan R Wiblin, Miles W. Carroll, Breeze E. Cavell, Charlotte Sarfas, Simon G. P. Funnell, Francisco J. Salguero, Karen R. Buttigieg, Carrie Turner, Kevin R. Bewley, Jade Gouriet, Yper Hall, Marilyn Aram, Kathryn A. Ryan, Adam Mabbutt, Steve Pullan, Konstantinos Gkolfinos, Julia A. Tree, Geoffrey Pearson, Lauren Allen, Debbie J Harris, Andrew G. Nicholson, Sue Charlton, Alistair C. Darby, Naomi Coombes, Edith Vamos, Daniel Knott, Karen E. Gooch, Catherine M K Ho, Stephanie Longet, Chelsea L Kennard, Julian A. Hiscox, Xiaofeng Dong, Jemma Paterson, Mike Dennis, Emma Rayner, Fergus V. Gleeson, Elizabeth J Penn, Sally Sharpe, Laura Sibley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
NATURE COMMUNICATIONS
Nature Communications
NATURE COMMUNICATIONS
Nature Communications
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to understand the pathogenesis of emerging diseases and to assess the saf
Autor:
Andrew D. White, Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Kevin Bewley, Colin Churchward, Susan Fotheringham, Konstantinos Gkolfinos, Karen Gooch, Alastair Handley, Holly E. Humphries, Laura Hunter, Chelsea Kennard, Stephanie Longet, Adam Mabbutt, Miriam Moffatt, Emma Rayner, Tom Tipton, Robert Watson, Yper Hall, Mark Bodman-Smith, Fergus Gleeson, Mike Dennis, Francisco J. Salguero, Miles Carroll, Helen McShane, William Cookson, Julian Hopkin, Sally Sharpe
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The tuberculosis vaccine, Bacille Calmette-Guerin (BCG), also affords protection against non-tuberculous diseases attributable to heterologous immune mechanisms such as trained innate immunity, activation of non-conventional T-cells, and cross-reacti